Search Results - "Davies, Chris D"

Optimization of a Novel Binding Motif to (E)‑3-(3,5-Difluoro-4-((1R,3R)‑2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro‑1H‑pyrido[3,4‑b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist by De Savi, Chris, Bradbury, Robert H, Rabow, Alfred A, Norman, Richard A, de Almeida, Camila, Andrews, David M, Ballard, Peter, Buttar, David, Callis, Rowena J, Currie, Gordon S, Curwen, Jon O, Davies, Chris D, Donald, Craig S, Feron, Lyman J. L, Gingell, Helen, Glossop, Steven C, Hayter, Barry R, Hussain, Syeed, Karoutchi, Galith, Lamont, Scott G, MacFaul, Philip, Moss, Thomas A, Pearson, Stuart E, Tonge, Michael, Walker, Graeme E, Weir, Hazel M, Wilson, Zena

“…The discovery of an orally bioavailable selective estrogen receptor downregulator (SERD) with equivalent potency and preclinical pharmacology to the…”
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Optimization of a Novel Binding Motif to ( E )-3-(3,5-Difluoro-4-((1 R ,3 R )-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1 H -pyrido[3,4- b ]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist by De Savi, Chris, Bradbury, Robert H., Rabow, Alfred A., Norman, Richard A., de Almeida, Camila, Andrews, David M., Ballard, Peter, Buttar, David, Callis, Rowena J., Currie, Gordon S., Curwen, Jon O., Davies, Chris D., Donald, Craig S., Feron, Lyman J. L., Gingell, Helen, Glossop, Steven C., Hayter, Barry R., Hussain, Syeed, Karoutchi, Galith, Lamont, Scott G., MacFaul, Philip, Moss, Thomas A., Pearson, Stuart E., Tonge, Michael, Walker, Graeme E., Weir, Hazel M., Wilson, Zena

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