Search Results - "Davies, C.R"

Longitudinal in vivo two-photon fluorescence imaging by Crowe, Sarah E., Ellis-Davies, Graham C.R.

“…ABSTRACT Fluorescence microscopy is an essential technique for the basic sciences, especially biomedical research. Since the invention of laser scanning…”
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In vivo characterization of a bigenic fluorescent mouse model of Alzheimer's disease with neurodegeneration by Crowe, Sarah E., Ellis-Davies, Graham C.R.

“…The loss of cognitive function in Alzheimer's disease (AD) patients is strongly correlated with the loss of neurons in various regions of the brain. We have…”
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Optical control of neuronal ion channels and receptors by Paoletti, Pierre, Ellis-Davies, Graham C. R., Mourot, Alexandre

“…Light-controllable tools provide powerful means to manipulate and interrogate brain function with relatively low invasiveness and high spatiotemporal…”
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A critical time window for dopamine actions on the structural plasticity of dendritic spines by Yagishita, Sho, Hayashi-Takagi, Akiko, Ellis-Davies, Graham C.R., Urakubo, Hidetoshi, Ishii, Shin, Kasai, Haruo

“…Animal behaviors are reinforced by subsequent rewards following within a narrow time window. Such reward signals are primarily coded by dopamine, which…”
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In vivo characterization of a bigenic fluorescent mouse model of Alzheimer's disease with neurodegeneration by Crowe, Sarah E., Ellis-Davies, Graham C.R.

“…The loss of cognitive function in Alzheimer's disease (AD) patients is strongly correlated with the loss of neurons in various regions of the brain. We have…”
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Caged compounds: photorelease technology for control of cellular chemistry and physiology by Ellis-Davies, Graham C R

“…Caged compounds are light-sensitive probes that functionally encapsulate biomolecules in an inactive form. Irradiation liberates the trapped molecule,…”
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Resistance of simple plant root systems to uplift loads by Mickovski, S. B, Bransby, M. F, Bengough, A. G, Davies, M. C.R, Hallett, P. D

“…Plant root systems frequently permeate both natural and engineered soil slopes, influencing slope stability via mechanical reinforcement and soil drying. These…”
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The Subspine Organization of Actin Fibers Regulates the Structure and Plasticity of Dendritic Spines by Honkura, Naoki, Matsuzaki, Masanori, Noguchi, Jun, Ellis-Davies, Graham C.R., Kasai, Haruo

“…Synapse function and plasticity depend on the physical structure of dendritic spines as determined by the actin cytoskeleton. We have investigated the…”
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Brain metabolism dictates the polarity of astrocyte control over arterioles by MacVicar, Brian A, Gordon, Grant R. J, Choi, Hyun B, Rungta, Ravi L, Ellis-Davies, Graham C. R

“…Calcium signalling in astrocytes couples changes in neural activity to alterations in cerebral blood flow by eliciting vasoconstriction or vasodilation of…”
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Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines by Tanaka, Jun-ichi, Horiike, Yoshihiro, Matsuzaki, Masanori, Miyazaki, Takashi, Ellis-Davies, Graham C.R, Kasai, Haruo

“…Long-term potentiation (LTP) at glutamatergic synapses is considered to underlie learning and memory and is associated with the enlargement of dendritic…”
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Recombinant Probes for Visualizing Endogenous Synaptic Proteins in Living Neurons by Gross, Garrett G., Junge, Jason A., Mora, Rudy J., Kwon, Hyung-Bae, Olson, C. Anders, Takahashi, Terry T., Liman, Emily R., Ellis-Davies, Graham C.R., McGee, Aaron W., Sabatini, Bernardo L., Roberts, Richard W., Arnold, Don B.

“…The ability to visualize endogenous proteins in living neurons provides a powerful means to interrogate neuronal structure and function. Here we…”
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Cloaked Caged Compounds: Chemical Probes for Two‐Photon Optoneurobiology by Richers, Matthew T., Amatrudo, Joseph M., Olson, Jeremy P., Ellis‐Davies, Graham C. R.

“…Caged neurotransmitters, in combination with focused light beams, enable precise interrogation of neuronal function, even at the level of single synapses…”
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Astrocyte-Mediated Distributed Plasticity at Hypothalamic Glutamate Synapses by Gordon, Grant R.J., Iremonger, Karl J., Kantevari, Srinivas, Ellis-Davies, Graham C.R., MacVicar, Brian A., Bains, Jaideep S.

“…Afferent activity can induce fast, feed-forward changes in synaptic efficacy that are synapse specific. Using combined electrophysiology, caged molecule…”
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Two-color, two-photon uncaging of glutamate and GABA by Kasai, Haruo, Ellis-Davies, Graham C R, Kantevari, Srinivas, Matsuzaki, Masanori, Kanemoto, Yuya

“…We developed a caged GABA (γ-aminobutyric acid), which, when combined with an appropriate caged glutamate, allows bimodal control of neuronal membrane…”
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Ca2+-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses by Zhai, Shenyu, Otsuka, Shintaro, Xu, Jian, Clarke, Vernon R.J., Tkatch, Tatiana, Wokosin, David, Xie, Zhong, Tanimura, Asami, Agarwal, Hitesh K., Ellis-Davies, Graham C.R., Contractor, Anis, Surmeier, D. James

“…Long-term synaptic plasticity at glutamatergic synapses on striatal spiny projection neurons (SPNs) is central to learning goal-directed behaviors and habits…”
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Thermodynamically Stable, Photoreversible Pharmacology in Neurons with One‐ and Two‐Photon Excitation by Passlick, Stefan, Richers, Matthew T., Ellis‐Davies, Graham C. R.

“…Photoswitchable bioprobes enable bidirectional control of cell physiology with different wavelengths of light. Many current photoswitches use cytotoxic UV…”
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Mechanical Reinforcement of Soil by Willow Roots: Impacts of Root Properties and Root Failure Mechanism by Mickovski, Slobodan B, Hallett, Paul D, Bransby, M. Fraser, Davies, Michael C.R, Sonnenberg, Rene, Bengough, A. Glyn

“…Plant roots have considerable impact on the mechanical stability of soil, but to date the underlying mechanisms have been poorly quantified. In this study,…”
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Synaptic deficits in layer 5 neurons precede overt structural decay in 5xFAD mice by Buskila, Y, Crowe, S.E, Ellis-Davies, G.C.R

“…Highlights • 5xFAD mice are a familial Alzheimer model with profound neocortical layer 5 neurodegeneration. • Layer 5 neurons in 5xFAD mice are structurally…”
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The nitrodibenzofuran chromophore: a new caging group for ultra-efficient photolysis in living cells by Ellis-Davies, Graham C R, Momotake, Atsuya, Lindegger, Nicolas, Niggli, Ernst, Barsotti, Robert J

“…Photochemical uncaging of bio-active molecules was introduced in 1977, but since then, there has been no substantial improvement in the properties of generic…”
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Platelet RNAs as potential biomarkers in prostate cancer detection: Highlighting differential expression of hsa-miR-627, hsa-miR-22, and hsa-miR-190 by Wang, X.K., Guo, T.Y., Gu, J.Y., Burke, E., Davies, C.R., Feng, N.H., Lu, Y-J.

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