Search Results - "Davidsohn, Matthew P."
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Liquid biopsy epigenomic profiling for cancer subtyping
Published in Nature medicine (01-11-2023)“…Although circulating tumor DNA (ctDNA) assays are increasingly used to inform clinical decisions in cancer care, they have limited ability to identify the…”
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The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response
Published in Cancer research (Chicago, Ill.) (16-08-2022)“…African-American (AA) men are more likely to be diagnosed with and die from prostate cancer than European American (EA) men. Despite the central role of the…”
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Detecting small cell transformation in patients with advanced EGFR mutant lung adenocarcinoma through epigenomic cfDNA profiling
Published in Clinical cancer research (03-09-2024)“…Histologic transformation to small cell lung cancer (SCLC) is a mechanism of treatment resistance in patients with advanced oncogene-driven lung adenocarcinoma…”
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Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping
Published in Nature medicine (01-03-2024)Get full text
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Clinical outcomes of volume of disease on patients receiving enzalutamide versus abiraterone acetate plus prednisone as first-line therapy for metastatic castration-resistant prostate cancer
Published in Therapeutic advances in medical oncology (01-01-2023)“…Background: Androgen receptor signaling inhibitors (ARSis) abiraterone acetate (AA) plus prednisone and enzalutamide (Enza), are currently the most…”
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Detection of neuroendocrine prostate cancer through plasma-based epigenomic profiling
Published in Journal of clinical oncology (01-02-2024)“…201 Background: Neuroendocrine prostate cancer (NEPC) is an aggressive resistance phenotype that can develop in men with metastatic prostate adenocarcinoma…”
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Outcomes with sacituzumab govitecan (SG) in patients (pts) with advanced urothelial carcinoma (aUC) and variant histologies (VH): Analysis of the UNITE study
Published in Journal of clinical oncology (01-02-2024)“…667 Background: SG is approved in pts with aUC refractory to platinum-based chemotherapy (PBT) and checkpoint inhibitor therapy (CPI). Data on SG outcomes in…”
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Outcomes in patients (pts) with advanced urothelial carcinoma (aUC) treated with enfortumab vedotin (EV) after switch maintenance avelumab (MAv) in the UNITE study
Published in Journal of clinical oncology (01-02-2024)“…537 Background: MAv is approved in pts with aUC without progression (PD) on 1L platinum-based therapy (PBT). As pts in the pivotal EV trials had not received…”
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Detection of sarcomatoid renal cell carcinoma using plasma cell-free DNA methylation
Published in Journal of clinical oncology (01-02-2024)“…449 Background: Sarcomatoid differentiation (SD) in renal cell carcinoma (RCC) is associated with poor survival and heightened response to immune checkpoint…”
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Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
Published in Cell reports (Cambridge) (25-06-2024)“…Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and a heightened response to immune checkpoint inhibitors (ICIs)…”
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Clinical outcomes of volume of disease on patients receiving enzalutamide abiraterone acetate plus prednisone as first-line therapy for metastatic castration-resistant prostate cancer
Published in Therapeutic advances in medical oncology (01-03-2023)“…Background: Androgen receptor signaling inhibitors (ARSis) abiraterone acetate (AA) plus prednisone and enzalutamide (Enza), are currently the most…”
Get full text
Journal Article