Search Results - "David S. Knopman MD"

Mild Cognitive Impairment and Mild Dementia: A Clinical Perspective by Knopman, David S., MD, Petersen, Ronald C., PhD, MD

“…Abstract Mild cognitive impairment and mild dementia are common problems in the elderly. Primary care physicians are the first point of contact for most…”
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Classification and Epidemiology of MCI by Roberts, Rosebud, MS, MB ChB, Knopman, David S., MD

“…Mild cognitive impairment (MCI) is an intermediate stage in the trajectory from normal cognition to dementia. Despite controversies about the classification of…”
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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade by Jack, Clifford R, MD, Knopman, David S, MD, Jagust, William J, MD, Shaw, Leslie M, PhD, Aisen, Paul S, MD, Weiner, Michael W, MD, Petersen, Ronald C, MD, Trojanowski, John Q, PhD

“…Summary Currently available evidence strongly supports the position that the initiating event in Alzheimer's disease (AD) is related to abnormal processing of…”
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White Matter Integrity on DTI and the Pathologic Staging of Alzheimer’s Disease by Kantarci, Kejal, MD, MS, Murray, Melissa E., PhD, Schwarz, Christopher G., PhD, Reid, Robert, PhD, Przybelski, Scott A, Lesnick, Timothy, MS, Zuk, Samantha M, Raman, Mekala R., PhD, Senjem, Matthew L., MS, Gunter, Jeffrey L., PhD, Boeve, Bradley F., MD, Knopman, David S., MD, Parisi, Joseph E., MD, Petersen, Ronald C., MD, PhD, Jack, Clifford R., MD, Dickson, Dennis, MD

“…Abstract Pattern of diffusion tensor MRI (DTI) alterations were investigated in pathologically-staged Alzheimer’s disease (AD) patients (n=46). Patients with…”
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Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial by Boxer, Adam L, Dr, Knopman, David S, MD, Kaufer, Daniel I, MD, Grossman, Murray, MD, Onyike, Chiadi, MD, Graf-Radford, Neill, MD, Mendez, Mario, MD, Kerwin, Diana, MD, Lerner, Alan, MD, Wu, Chuang-Kuo, MD, Koestler, Mary, PhD, Shapira, Jill, RN, Sullivan, Kathryn, BS, Klepac, Kristen, BS, Lipowski, Kristine, Ullah, Jerin, MS, Fields, Scott, PharmD, Kramer, Joel H, PsyD, Merrilees, Jennifer, PhD, Neuhaus, John, PhD, Mesulam, M Marsel, MD, Miller, Bruce L, MD

“…Summary Background Memantine has been used off-label to treat frontotemporal lobar degeneration (FTD). A previous 26-week open-label study suggested a…”
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Cognitive Impairment in CKD: No Longer an Occult Burden by Murray, Anne M., MD, MSc, Knopman, David S., MD

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Anesthesia and Incident Dementia: A Population-Based, Nested, Case-Control Study by Sprung, Juraj, MD, PhD, Jankowski, Christopher J., MD, Roberts, Rosebud O., MD, Weingarten, Toby N., MD, Aguilar, Andrea L., SRNA, Runkle, Kayla J., SRNA, Tucker, Amanda K., SRNA, McLaren, Kathryn C., RN, Schroeder, Darrell R., MS, Hanson, Andrew C., BS, Knopman, David S., MD, Gurrieri, Carmelina, MD, Warner, David O., MD

“…Abstract Objective To test the hypothesis that exposure to procedures requiring general anesthesia during adulthood is not significantly associated with…”
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The Brain in Kidney Disease (BRINK) Cohort Study: Design and Baseline Cognitive Function by Murray, Anne M., MD, MSc, Bell, Elizabeth J., PhD, MPH, Tupper, David E., PhD, Davey, Cynthia S., MS, Pederson, Sarah L., MA, MBA, Amiot, Elizabeth M., BA, Miley, Kathleen M., CNP, McPherson, Lauren, BS, Heubner, Brooke M., MS, Gilbertson, David T., PhD, Foley, Robert N., MBBS, Drawz, Paul E., MD, Slinin, Yelena, MD, MS, Rossom, Rebecca C., MD, MS, Lakshminarayan, Kamakshi, MD, PhD, Vemuri, Prashanthi, PhD, Jack, Clifford R., MD, Knopman, David S., MD

“…Background The Brain in Kidney Disease (BRINK) Study aims to identify mechanisms that contribute to increased risk for cognitive impairment in patients with…”
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Alzheimer Disease by Caselli, Richard J., MD, Beach, Thomas G., MD, PhD, Knopman, David S., MD, Graff-Radford, Neill R., MD

“…Abstract Alzheimer disease (AD) was originally conceived as a rare disease that caused presenile dementia but has come to be understood as the most prevalent…”
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Evolution of Neurodegeneration Imaging Biomarkers from Clinically Normal to Dementia in the Alzheimer Disease Spectrum by Knopman, David S., MD, Jack, Clifford R., MD, Lundt, Emily S., MS, Weigand, Stephen D., MS, Vemuri, Prashanthi, PhD, Lowe, Val J., MD, Kantarci, Kejal, MD, Gunter, Jeffrey L., PhD, Senjem, Matthew L., MS, Mielke, Michelle M., PhD, Machulda, Mary M., PhD, Roberts, Rosebud O., MBChB, Boeve, Bradley F., MD, Jones, David T., MD, Petersen, Ronald C., MD, PhD

“…Abstract The availability of antemortem biomarkers for Alzheimer’s Disease (AD) enables monitoring the evolution of neurodegenerative processes in real time…”
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Computer Activities, Physical Exercise, Aging, and Mild Cognitive Impairment: A Population-Based Study by Geda, Yonas E., MD, MSc, Silber, Taryn C, Roberts, Rosebud O., MBChB, MS, Knopman, David S., MD, Christianson, Teresa J.H., BSc, Pankratz, V. Shane, PhD, Boeve, Bradley F., MD, Tangalos, Eric G., MD, Petersen, Ronald C., MD, PhD

“…Abstract Objective To examine the association between computer use, physical exercise, aging, and mild cognitive impairment (MCI). Patients and Methods The…”
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Perioperative Delirium and Mild Cognitive Impairment by Sprung, Juraj, MD, PhD, Roberts, Rosebud O., MB ChB, MS, Knopman, David S., MD, Petersen, Ronald C., MD, PhD, Weingarten, Toby N., MD, Schroeder, Darrell R., MS, Warner, David O., MD

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First PET Imaging Studies With Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease by Timothy R. DeGrado PhD, Bradley J. Kemp PhD, Mukesh K. Pandey PhD, Huailei Jiang PhD, Tina M. Gunderson MS, Logan R. Linscheid CNMT, Allison R. Woodwick CNMT, Daniel M. McConnell CNMT, Joel G. Fletcher MD, Geoffrey B. Johnson MD, PhD, Ronald C. Petersen MD, PhD, David S. Knopman MD, Val J. Lowe MD

“…Abnormalities in zinc homeostasis are indicated in many human diseases, including Alzheimer disease (AD). 63 Zn-zinc citrate was developed as a positron…”
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Incident Heart Failure and Cognitive Decline: The Atherosclerosis Risk in Communities Study by Bressler, Jan, PhD, Knopman, David S., MD, Sharrett, A. Richey, MD, DrPH, Gottesman, Rebecca F., MD, PhD, Penman, Alan, MB, ChB, PhD, MPH, Chang, Patricia P., MD, MHS, Rosamond, Wayne D., PhD, Boerwinkle, Eric, PhD, Mosley, Thomas H., PhD

“…Abstract Background Cognitive impairment is found in a significant proportion of patients with heart failure (HF). Although cognitive impairment may be a…”
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Association of Mild Cognitive Impairment With Exposure to General Anesthesia for Surgical and Nonsurgical Procedures by Sprung, Juraj, MD, PhD, Roberts, Rosebud O., MB ChB, MS, Knopman, David S., MD, Olive, Diana M., CRNA, Gappa, Jennie L., CRNA, Sifuentes, Valerie L., CRNA, Behrend, Travis L., MD, Farmer, Joel D., MD, Weingarten, Toby N., MD, Hanson, Andrew C., BS, Schroeder, Darrell R., MS, Petersen, Ronald C., MD, PhD, Warner, David O., MD

“…Abstract Objective To examine whether exposure to general anesthesia for operations and procedures after the age of 40 years is associated with incident mild…”
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RAB39B gene is not a common cause of Parkinson’s disease or dementia with Lewy bodies by Hodges, Kyndall, Brewer, Sheridan S, Labbé, Catherine, PhD, Soto-Ortolaza, Alexandra I., BSc, Walton, Ronald L., BSc, Strongosky, Audrey J, Uitti, Ryan J., MD, van Gerpen, Jay A., MD, Ertekin-Taner, Nilüfer, MD, PhD, Kantarci, Kejal, MD, Lowe, Val J., MD, Parisi, Joseph E., MD, Savica, Rodolfo, MD, PhD, Graff-Radford, Jonathan, MD, Jones, David T., MD, Knopman, David S., MD, Petersen, Ronald C., MD, PhD, Murray, Melissa E., PhD, Graff-Radford, Neill R., MD, Ferman, Tanis J., PhD, Dickson, Dennis W., MD, Wszolek, Zbigniew K., MD, Boeve, Bradley F., MD, Ross, Owen A., PhD, Lorenzo-Betancor, Oswaldo, MD, PhD

“…Abstract Mutations in RAB39B gene have been linked to X-linked early onset Parkinsonism with intellectual disabilities. The aim of this study was to address…”
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Conflicts of Interest, Authorship, and Disclosures in Industry-Related Scientific Publications–1 by Baskin, Patricia K., MS, Knopman, David S., MD, Gross, Robert A., MD, PhD

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