Search Results - "David Rizo‐Roca"

Self-Paced Free-Running Wheel Mimics High-Intensity Interval Training Impact on Rats' Functional, Physiological, Biochemical, and Morphological Features by Beleza, Jorge, Albuquerque, João, Santos-Alves, Estela, Fonseca, Pedro, Santocildes, Garoa, Stevanovic, Jelena, Rocha-Rodrigues, Sílvia, Rizo-Roca, David, Ascensão, António, Torrella, Joan Ramon, Magalhães, José

“…Free-running wheel (FRW) is an animal exercise model that relies on high-intensity interval moments interspersed with low-intensity or pauses apparently…”
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Contractile Activity Is Necessary to Trigger Intermittent Hypobaric Hypoxia-Induced Fiber Size and Vascular Adaptations in Skeletal Muscle by Rizo-Roca, David, Bonet, Jèssica B, Ínal, Büsra, Ríos-Kristjánsson, Juan Gabriel, Pagès, Teresa, Viscor, Ginés, Torrella, Joan R

“…Altitude training has become increasingly popular in recent decades. Its central and peripheral effects are well-described; however, few studies have analyzed…”
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Exercise mitigates diclofenac-induced liver mitochondrial dysfunction by Santos-Alves, Estela, Marques-Aleixo, Ines, Coxito, Pedro, Balça, Maria M., Rizo-Roca, David, Rocha-Rodrigues, Silvia, Martins, Sandra, Torrella, Joan R., Oliveira, Paulo J., Moreno, Antonio J., Magalhães, José, Ascensão, António

“…Background Several strategies have been developed to counteract liver injury as a consequence of nonsteroid anti‐inflammatory drugs toxicity. Here, we aimed to…”
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Metabolic mitochondrial alterations prevail in the female rat heart 8 weeks after exercise cessation by Tocantins, Carolina, Martins, João D, Rodrigues, Óscar M, Grilo, Luís F, Diniz, Mariana S, Stevanovic-Silva, Jelena, Beleza, Jorge, Coxito, Pedro, Rizo-Roca, David, Santos-Alves, Estela, Rios, Manoel, Carvalho, Lina, Moreno, António J, Ascensão, António, Magalhães, José, Oliveira, Paulo J, Pereira, Susana P

“…The consumption of high-caloric diets strongly contributes to the development of non-communicable diseases (NCDs), including cardiovascular disease, the…”
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Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress by Marques-Aleixo, Inês, Santos-Alves, Estela, Mariani, Diogo, Rizo-Roca, David, Padrão, Ana I, Rocha-Rodrigues, Sílvia, Viscor, Ginés, Torrella, J Ramon, Ferreira, Rita, Oliveira, Paulo J, Magalhães, José, Ascensão, António

“…Doxorubicin (DOX) is an anti-cancer agent whose clinical usage results in a cumulative and dose-dependent cardiotoxicity. We have previously shown that…”
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Physical exercise positively modulates DOX-induced hepatic oxidative stress, mitochondrial dysfunction and quality control signaling by Santos-Alves, Estela, Rizo-Roca, David, Marques-Aleixo, Inês, Coxito, Pedro, Martins, Sandra, Guimarães, João T, Oliveira, Paulo J, Torrella, Joan R, Magalhães, José, Ascensão, António

“…Doxorubicin (DOX), a widely used and efficient antineoplastic agent, is mainly limited by cardiotoxicity, although other tissues including liver are also…”
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A three-criteria performance score for rats exercising on a running treadmill by Ríos-Kristjánsson, Juan Gabriel, Rizo-Roca, David, Kristjánsdóttir, Karen Mist, Núñez-Espinosa, Cristian Andrés, Torrella, Joan Ramon, Pagès, Teresa, Viscor, Ginés

“…In this study, we propose a novel three-criteria performance score to semiquantitatively classify the running style, the degree of involvement and compliance…”
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Concerted regulation of skeletal muscle metabolism and contractile properties by the orphan nuclear receptor Nr2f6 by Guimarães, Dimitrius Santiago P. S. F., Barrios, Ninon M. F., Oliveira, André Gustavo, Rizo‐Roca, David, Jollet, Maxence, Smith, Jonathon A.B., Araujo, Thiago R., Cruz, Marcos Vinicius, Marconato, Emilio, Hirabara, Sandro M., Vieira, André S., Krook, Anna, Zierath, Juleen R., Silveira, Leonardo R.

“…Background The maintenance of skeletal muscle plasticity upon changes in the environment, nutrient supply, and exercise depends on regulatory mechanisms that…”
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Additive Effects of Intermittent Hypobaric Hypoxia and Endurance Training on Bodyweight, Food Intake, and Oxygen Consumption in Rats by Cabrera-Aguilera, Ignacio, Rizo-Roca, David, Marques, Elisa A, Santocildes, Garoa, Pagès, Teresa, Viscor, Gines, Ascensão, António A, Magalhães, José, Torrella, Joan Ramon

“…Cabrera-Aguilera, Ignacio, David Rizo-Roca, Elisa A. Marques, Garoa Santocildes, Teresa Pagès, Gines Viscor, António A. Ascensão, José Magalhães, and Joan…”
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Effects of intermittent hypoxia and light aerobic exercise on circulating stem cells and side population, after strenuous eccentric exercise in trained rats by Núñez-Espinosa, Cristian, Ferreira, Inês, Ríos-Kristjánsson, Juan Gabriel, Rizo-Roca, David, García Godoy, Maria Dolors, Rico, Laura G, Rubi-Sans, Gerard, Torrella, Joan Ramon, Pagès, Teresa, Petriz, Jordi, Viscor, Ginés

“…Our goal was to address if intermittent hypobaric hypoxia (IHH) exposure can help to increase the number of peripheral blood circulating progenitor cells and…”
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Vybrant DyeCycle Violet Stain Discriminates Two Different Subsets of CD34+ Cells by Núñez-Espinosa, Cristian, García-Godoy, María D, Ferreira, Inês, Ríos-Kristjánsson, Juan G, Rizo-Roca, David, Rico, Laura G, Rubí-Sans, Gerard, Palacio, Carlos, Torrella, Joan R, Pagès, Teresa, Ward, Mike D, Viscor, Ginés, Petriz, Jordi

“…Studies are needed to understand the role of CD34 expressing cells with regard to efficient engraftment, especially in the adjuvant treatment of cancer. In…”
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Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes by Dollet, Lucile, Kuefner, Michael, Caria, Elena, Rizo-Roca, David, Pendergrast, Logan, Abdelmoez, Ahmed M, Karlsson, Håkan K R, Bjrnholm, Marie, Dalbram, Emilie, Treebak, Jonas T, Harada, Jun, Näslund, Erik, Rydén, Mikael, Zierath, Juleen R, Pillon, Nicolas J, Krook, Anna

“…Dysregulation of skeletal muscle metabolism influences whole-body insulin sensitivity and glucose homeostasis. We hypothesized that type 2 diabetes-associated…”
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Sex-Specific Impact of Maternal Obesity and Gestational Exercise on Offspring's Cardiac Health: Insights into Mitochondrial Function and NO Signaling by Pereira, Susana P., Diniz, Mariana S., Martins, João D., Rodrigues, Óscar M., Tocantins, Carolina, Grilo, Luís F., Carvalho, Lina, Stevanovic-Silva, Jelena, Beleza, Jorge, Coxito, Pedro, Rizo-Roca, David, Santos-Alves, Estela, Rios, Manoel, Moreno, António J., Ascensão, António, Magalhães, José, Oliveira, Paulo J.

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Physical exercise mitigates behavioral impairments in a rat model of sporadic Alzheimer’s disease by Bernardo, Telma C., Beleza, Jorge, Rizo-Roca, David, Santos-Alves, Estela, Leal, Cláudia, Martins, Maria João, Ascensão, António, Magalhães, José

“…•Endurance training improves spatial learning and long-term memory in icv STZ rats.•Endurance training ameliorates cerebral bioenergetical deficits in icv STZ…”
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Maternal heart exhibits metabolic and redox adaptations post-uncomplicated pregnancy by Tocantins, Carolina, Martins, João D., Rodrigues, Óscar M., Grilo, Luís F., Diniz, Mariana S., Stevanovic-Silva, Jelena, Beleza, Jorge, Coxito, Pedro, Rizo-Roca, David, Santos-Alves, Estela, Moreno, António J., Ascensão, António, Magalhães, José, Oliveira, Paulo J., Pereira, Susana P.

“…Pregnancy may be a challenging period for the maternal systems and has been regarded as a stress test, as imperceptible/mild dysfunctions eventually present…”
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Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes by Sjögren, Rasmus J. O., Rizo-Roca, David, Chibalin, Alexander V., Chorell, Elin, Furrer, Regula, Katayama, Shintaro, Harada, Jun, Karlsson, Håkan K. R., Handschin, Christoph, Moritz, Thomas, Krook, Anna, Näslund, Erik, Zierath, Juleen R.

“…Aims/hypothesis Increased levels of branched-chain amino acids (BCAAs) are associated with type 2 diabetes pathogenesis. However, most metabolomic studies are…”
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Metabolic mitochondrial alterations prevail in the female rat heart 8weeks after exercise cessation by Tocantins, Carolina, Martins, João D, Rodrigues, Óscar M, Grilo, Luís F, Diniz, Mariana S, Jelena Stevanovic‐Silva, Beleza, Jorge, Coxito, Pedro, David Rizo‐Roca, Estela Santos‐Alves, Rios, Manoel, Carvalho, Lina, Moreno, António J, Ascensão, António, Magalhães, José, Oliveira, Paulo J, Pereira, Susana P

“…BackgroundThe consumption of high‐caloric diets strongly contributes to the development of non‐communicable diseases (NCDs), including cardiovascular disease,…”
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Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes by Rizo-Roca, David, Guimarães, Dimitrius Santiago P S F, Pendergrast, Logan A, Di Leo, Nicolas, Chibalin, Alexander V, Maqdasy, Salwan, Rydén, Mikael, Näslund, Erik, Zierath, Juleen R, Krook, Anna

“…Increased plasma creatine concentrations are associated with the risk of type 2 diabetes, but whether this alteration is associated with or causal for…”
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Swimming-induced exercise promotes hypertrophy and vascularization of fast skeletal muscle fibres and activation of myogenic and angiogenic transcriptional programs in adult zebrafish by Palstra, Arjan P, Rovira, Mireia, Rizo-Roca, David, Torrella, Joan Ramon, Spaink, Herman P, Planas, Josep V

“…The adult skeletal muscle is a plastic tissue with a remarkable ability to adapt to different levels of activity by altering its excitability, its contractile…”
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Postinjury Exercise and Platelet-Rich Plasma Therapies Improve Skeletal Muscle Healing in Rats But Are Not Synergistic When Combined by Contreras-Muñoz, Paola, Torrella, Joan Ramon, Serres, Xavier, Rizo-Roca, David, De la Varga, Meritxell, Viscor, Ginés, Martínez-Ibáñez, Vicente, Peiró, José Luis, Järvinen, Tero A. H., Rodas, Gil, Marotta, Mario

“…Background: Skeletal muscle injuries are the most common sports-related injury and a major concern in sports medicine. The effect of platelet-rich plasma (PRP)…”
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