Search Results - "David Meekins"

Serpins in arthropod biology by Meekins, David A, Kanost, Michael R, Michel, Kristin

“…Serpins are the largest known family of serine proteinase inhibitors and perform a variety of physiological functions in arthropods. Herein, we review the…”
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Natural and Experimental SARS-CoV-2 Infection in Domestic and Wild Animals by Meekins, David A, Gaudreault, Natasha N, Richt, Juergen A

“…SARS-CoV-2 is the etiological agent responsible for the ongoing COVID-19 pandemic, which continues to spread with devastating effects on global health and…”
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Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission by Escalera, Alba, Gonzalez-Reiche, Ana S., Aslam, Sadaf, Mena, Ignacio, Laporte, Manon, Pearl, Rebecca L., Fossati, Andrea, Rathnasinghe, Raveen, Alshammary, Hala, van de Guchte, Adriana, Farrugia, Keith, Qin, Yiren, Bouhaddou, Mehdi, Kehrer, Thomas, Zuliani-Alvarez, Lorena, Meekins, David A., Balaraman, Velmurugan, McDowell, Chester, Richt, Jürgen A., Bajic, Goran, Sordillo, Emilia Mia, Dejosez, Marion, Zwaka, Thomas P., Krogan, Nevan J., Simon, Viviana, Albrecht, Randy A., van Bakel, Harm, García-Sastre, Adolfo, Aydillo, Teresa

“…SARS-CoV-2 lineages have diverged into highly prevalent variants termed “variants of concern” (VOCs). Here, we characterized emerging SARS-CoV-2 spike…”
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Mechanistic Insights into Dye-Decolorizing Peroxidase Revealed by Solvent Isotope and Viscosity Effects by Shrestha, Ruben, Huang, Gaochao, Meekins, David A, Geisbrecht, Brian V, Li, Ping

“…Dye-decolorizing peroxidases (DyPs) are a family of H2O2-dependent heme peroxidases that have shown potential applications in lignin degradation and…”
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SARS-CoV-2 infection, disease and transmission in domestic cats by Gaudreault, Natasha N., Trujillo, Jessie D., Carossino, Mariano, Meekins, David A., Morozov, Igor, Madden, Daniel W., Indran, Sabarish V., Bold, Dashzeveg, Balaraman, Velmurugan, Kwon, Taeyong, Artiaga, Bianca Libanori, Cool, Konner, García-Sastre, Adolfo, Ma, Wenjun, Wilson, William C., Henningson, Jamie, Balasuriya, Udeni B. R., Richt, Juergen A.

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19) and responsible for the current pandemic…”
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Development of a sensitive, high-throughput extraction protocol for qPCR detection of African swine fever virus in formalin-fixed, paraffin-embedded tissues by Urbaniak, Kinga, Meekins, David A., Davis, A. Sally, Richt, Juergen A., Trujillo, Jessie D.

“…African swine fever (ASF) causes fatal disease in pigs and is an escalating threat to the global swine industry. ASF has re-emerged from Africa as a…”
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Mechanical transmission of SARS-CoV-2 by house flies by Balaraman, Velmurugan, Drolet, Barbara S, Mitzel, Dana N, Wilson, William C, Owens, Jeana, Gaudreault, Natasha N, Meekins, David A, Bold, Dashzeveg, Trujillo, Jessie D, Noronha, Leela E, Richt, Juergen A, Nayduch, Dana

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged coronavirus that is the causative agent of the coronavirus disease 2019…”
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Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer by Cool, Konner, Gaudreault, Natasha N., Morozov, Igor, Trujillo, Jessie D., Meekins, David A., McDowell, Chester, Carossino, Mariano, Bold, Dashzeveg, Mitzel, Dana, Kwon, Taeyong, Balaraman, Velmurugan, Madden, Daniel W., Artiaga, Bianca Libanori, Pogranichniy, Roman M., Roman-Sosa, Gleyder, Henningson, Jamie, Wilson, William C., Balasuriya, Udeni B. R., García-Sastre, Adolfo, Richt, Juergen A.

“…SARS-CoV-2 was first reported circulating in human populations in December 2019 and has since become a global pandemic. Recent history involving SARS-like…”
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Susceptibility of swine cells and domestic pigs to SARS-CoV-2 by Meekins, David A., Morozov, Igor, Trujillo, Jessie D., Gaudreault, Natasha N., Bold, Dashzeveg, Carossino, Mariano, Artiaga, Bianca L., Indran, Sabarish V., Kwon, Taeyong, Balaraman, Velmurugan, Madden, Daniel W., Feldmann, Heinz, Henningson, Jamie, Ma, Wenjun, Balasuriya, Udeni B. R., Richt, Juergen A.

“…The emergence of SARS-CoV-2 has resulted in an ongoing global pandemic with significant morbidity, mortality, and economic consequences. The susceptibility of…”
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Cooperative Kinetics of the Glucan Phosphatase Starch Excess4 by Mak, Claudia A., Weis, Kenyon, Henao, Tiffany, Kuchtova, Andrea, Chen, Tiantian, Sharma, Savita, Meekins, David A., Thalmann, Matthias, Vander Kooi, Craig W., Raththagala, Madushi

“…Glucan phosphatases are members of a functionally diverse family of dual-specificity phosphatase (DSP) enzymes. The plant glucan phosphatase Starch Excess4…”
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Unique carbohydrate binding platforms employed by the glucan phosphatases by Emanuelle, Shane, Brewer, M. Kathryn, Meekins, David A., Gentry, Matthew S.

“…Glucan phosphatases are a family of enzymes that are functionally conserved at the enzymatic level in animals and plants. These enzymes bind and…”
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Phosphoglucan-bound structure of starch phosphatase Starch Excess4 reveals the mechanism for C6 specificity by Meekins, David A., Raththagala, Madushi, Husodo, Satrio, White, Cory J., Guo, Hou-Fu, Kötting, Oliver, Vander Kooi, Craig W., Gentry, Matthew S.

“…Plants use the insoluble polyglucan starch as their primary glucose storage molecule. Reversible phosphorylation, at the C6 and C3 positions of glucose…”
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Experimental re-infected cats do not transmit SARS-CoV-2 by Gaudreault, Natasha N., Carossino, Mariano, Morozov, Igor, Trujillo, Jessie D., Meekins, David A., Madden, Daniel W., Cool, Konner, Artiaga, Bianca Libanori, McDowell, Chester, Bold, Dashzeveg, Balaraman, Velmurugan, Kwon, Taeyong, Ma, Wenjun, Henningson, Jamie, Wilson, Dennis W., Wilson, William C., Balasuriya, Udeni B. R., García-Sastre, Adolfo, Richt, Juergen A.

“…SARS-CoV-2 is the causative agent of COVID-19 and responsible for the current global pandemic. We and others have previously demonstrated that cats are…”
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Structural Mechanism of Laforin Function in Glycogen Dephosphorylation and Lafora Disease by Raththagala, Madushi, Brewer, M. Kathryn, Parker, Matthew W., Sherwood, Amanda R., Wong, Brian K., Hsu, Simon, Bridges, Travis M., Paasch, Bradley C., Hellman, Lance M., Husodo, Satrio, Meekins, David A., Taylor, Adam O., Turner, Benjamin D., Auger, Kyle D., Dukhande, Vikas V., Chakravarthy, Srinivas, Sanz, Pascual, Woods, Virgil L., Li, Sheng, Vander Kooi, Craig W., Gentry, Matthew S.

“…Glycogen is the major mammalian glucose storage cache and is critical for energy homeostasis. Glycogen synthesis in neurons must be tightly controlled due to…”
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Structural mechanisms of plant glucan phosphatases in starch metabolism by Meekins, David A., Vander Kooi, Craig W., Gentry, Matthew S.

“…Glucan phosphatases are a recently discovered class of enzymes that dephosphorylate starch and glycogen, thereby regulating energy metabolism. Plant genomes…”
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Rift Valley Fever Phlebovirus Reassortment Study in Sheep by Balaraman, Velmurugan, Indran, Sabarish V, Kim, In Joong, Trujillo, Jessie D, Meekins, David A, Shivanna, Vinay, Zajac, Michelle D, Urbaniak, Kinga, Morozov, Igor, Sunwoo, Sun-Young, Faburay, Bonto, Osterrieder, Klaus, Gaudreault, Natasha N, Wilson, William C, Richt, Juergen A

“…Rift Valley fever (RVF) in ungulates and humans is caused by a mosquito-borne RVF phlebovirus (RVFV). Live attenuated vaccines are used in livestock (sheep and…”
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Effects of Spike Mutations in SARS-CoV-2 Variants of Concern on Human or Animal ACE2-Mediated Virus Entry and Neutralization by Kim, Yunjeong, Gaudreault, Natasha N, Meekins, David A, Perera, Krishani D, Bold, Dashzeveg, Trujillo, Jessie D, Morozov, Igor, McDowell, Chester D, Chang, Kyeong-Ok, Richt, Juergen A

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a zoonotic agent capable of infecting humans and a wide range of animal species. Over the…”
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The Phosphoglucan Phosphatase Like Sex Four2 Dephosphorylates Starch at the C3-Position in Arabidopsis by Santelia, Diana, Kötting, Oliver, Seung, David, Schubert, Mario, Thalmann, Matthias, Bischof, Sylvain, Meekins, David A., Lutz, Andy, Patron, Nicola, Gentry, Matthew S., Allain, Frédéric H.-T., Zeeman, Samuel C.

“…Starch contains phosphate covalently bound to the C6-position (70 to 80% of total bound phosphate) and the C3-position (20 to 30%) of the glucosyl residues of…”
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Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant by Gaudreault, Natasha N., Cool, Konner, Trujillo, Jessie D., Morozov, Igor, Meekins, David A., McDowell, Chester, Bold, Dashzeveg, Carossino, Mariano, Balaraman, Velmurugan, Mitzel, Dana, Kwon, Taeyong, Madden, Daniel W., Artiaga, Bianca Libanori, Pogranichniy, Roman M., Roman-Sosa, Gleyder, Wilson, William C., Balasuriya, Udeni B. R., García-Sastre, Adolfo, Richt, Juergen A.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for a global pandemic that has had significant impacts on human health and…”
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Exosomes induce neurogenesis of pluripotent P19 cells by Anji, Antje, Anderson, Briana, Akhtar, Feroz, Meekins, David A, Ito, Takashi, Mummidi, Srinivas, Kumari, Meena

“…Exosomes play a role in tissue/organ development and differentiation. Retinoic acid induces differentiation of P19 cells (UD-P19) to P19 neurons (P19N) that…”
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