Search Results - "David Knapp"

Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals by Sawai, Catherine M., Babovic, Sonja, Upadhaya, Samik, Knapp, David J.H.F., Lavin, Yonit, Lau, Colleen M., Goloborodko, Anton, Feng, Jue, Fujisaki, Joji, Ding, Lei, Mirny, Leonid A., Merad, Miriam, Eaves, Connie J., Reizis, Boris

“…Hematopoietic stem cells (HSCs) sustain long-term reconstitution of hematopoiesis in transplantation recipients, yet their role in the endogenous steady-state…”
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The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells by Copley, Michael R., Babovic, Sonja, Benz, Claudia, Knapp, David J. H. F., Beer, Philip A., Kent, David G., Wohrer, Stefan, Treloar, David Q., Day, Christopher, Rowe, Keegan, Mader, Heidi, Kuchenbauer, Florian, Humphries, R. Keith, Eaves, Connie J.

“…Mouse haematopoietic stem cells (HSCs) undergo a postnatal transition in several properties, including a marked reduction in their self-renewal activity. We…”
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Extreme differences in forest degradation in Borneo: comparing practices in Sarawak, Sabah, and Brunei by Bryan, Jane E, Shearman, Philip L, Asner, Gregory P, Knapp, David E, Aoro, Geraldine, Lokes, Barbara

“…The Malaysian states of Sabah and Sarawak are global hotspots of forest loss and degradation due to timber and oil palm industries; however, the rates and…”
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Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal by Fares, Iman, Chagraoui, Jalila, Gareau, Yves, Gingras, Stéphane, Ruel, Réjean, Mayotte, Nadine, Csaszar, Elizabeth, Knapp, David J. H. F., Miller, Paul, Ngom, Mor, Imren, Suzan, Roy, Denis-Claude, Watts, Kori L., Kiem, Hans-Peter, Herrington, Robert, Iscove, Norman N., Humphries, R. Keith, Eaves, Connie J., Cohen, Sandra, Marinier, Anne, Zandstra, Peter W., Sauvageau, Guy

“…The small number of hematopoietic stem and progenitor cells in cord blood units limits their widespread use in human transplant protocols. We identified a…”
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Progressive forest canopy water loss during the 2012–2015 California drought by Asner, Gregory P., Brodrick, Philip G., Anderson, Christopher B., Vaughn, Nicholas, Knapp, David E., Martin, Roberta E.

“…The 2012–2015 drought has left California with severely reduced snowpack, soil moisture, ground water, and reservoir stocks, but the impact of this estimated…”
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Quantifying forest canopy traits: Imaging spectroscopy versus field survey by Asner, Gregory P., Martin, Roberta E., Anderson, Christopher B., Knapp, David E.

“…Spatial and temporal information on plant functional traits are lacking in ecology, which limits our understanding of how plant communities and ecosystems are…”
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A General Solution for Unstable Boronic Acids: Slow-Release Cross-Coupling from Air-Stable MIDA Boronates by Knapp, David M, Gillis, Eric P, Burke, Martin D

“…Many boronic acids, including 2-heterocyclic, vinyl, and cyclopropyl derivatives, are inherently unstable, which can limit their benchtop storage and/or…”
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Adaptive bathymetry estimation for shallow coastal waters using Planet Dove satellites by Li, Jiwei, Knapp, David E., Schill, Steven R., Roelfsema, Chris, Phinn, Stuart, Silman, Miles, Mascaro, Joseph, Asner, Gregory P.

“…Accurate bathymetric mapping of shallow waters (above 15 m) is essential for a wide range of scientific research, government, transport, and industry globally…”
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H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells by Godfrey, Laura, Crump, Nicholas T., O’Byrne, Sorcha, Lau, I-Jun, Rice, Siobhan, Harman, Joe R., Jackson, Thomas, Elliott, Natalina, Buck, Gemma, Connor, Christopher, Thorne, Ross, Knapp, David J. H. F., Heidenreich, Olaf, Vyas, Paresh, Menendez, Pablo, Inglott, Sarah, Ancliff, Philip, Geng, Huimin, Roberts, Irene, Roy, Anindita, Milne, Thomas A.

“…MLL gene rearrangements (MLLr) are a common cause of aggressive, incurable acute lymphoblastic leukemias (ALL) in infants and children, most of which originate…”
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High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays by Lecault, Véronique, VanInsberghe, Michael, Sekulovic, Sanja, Knapp, David J H F, Wohrer, Stefan, Bowden, William, Viel, Francis, McLaughlin, Thomas, Jarandehei, Asefeh, Miller, Michelle, Falconnet, Didier, White, Adam K, Kent, David G, Copley, Michael R, Taghipour, Fariborz, Eaves, Connie J, Humphries, R Keith, Piret, James M, Hansen, Carl L

“…A microfluidic setup for nanoliter-volume perfused clonal culture and imaging of thousands of nonadherent cells is applied to study signaling and proliferation…”
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Precise tuning of gene expression levels in mammalian cells by Michaels, Yale S., Barnkob, Mike B., Barbosa, Hector, Baeumler, Toni A., Thompson, Mary K., Andre, Violaine, Colin-York, Huw, Fritzsche, Marco, Gileadi, Uzi, Sheppard, Hilary M., Knapp, David J. H. F., Milne, Thomas A., Cerundolo, Vincenzo, Fulga, Tudor A.

“…Precise, analogue regulation of gene expression is critical for cellular function in mammals. In contrast, widely employed experimental and therapeutic…”
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Large-scale climatic and geophysical controls on the leaf economics spectrum by Asner, Gregory P., Knapp, David E., Anderson, Christopher B., Martin, Roberta E., Vaughn, Nicholas

“…Leaf economics spectrum (LES) theory suggests a universal trade-off between resource acquisition and storage strategies in plants, expressed in relationships…”
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Automated Global Shallow Water Bathymetry Mapping Using Google Earth Engine by Li, Jiwei, Knapp, David E., Lyons, Mitchell, Roelfsema, Chris, Phinn, Stuart, Schill, Steven R., Asner, Gregory P.

“…Global shallow water bathymetry maps offer critical information to inform activities such as scientific research, environment protection, and marine…”
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A tale of two "forests": random forest machine learning AIDS tropical forest carbon mapping by Mascaro, Joseph, Asner, Gregory P, Knapp, David E, Kennedy-Bowdoin, Ty, Martin, Roberta E, Anderson, Christopher, Higgins, Mark, Chadwick, K Dana

“…Accurate and spatially-explicit maps of tropical forest carbon stocks are needed to implement carbon offset mechanisms such as REDD+ (Reduced Deforestation and…”
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Analysis of Normal Human Mammary Epigenomes Reveals Cell-Specific Active Enhancer States and Associated Transcription Factor Networks by Pellacani, Davide, Bilenky, Misha, Kannan, Nagarajan, Heravi-Moussavi, Alireza, Knapp, David J.H.F., Gakkhar, Sitanshu, Moksa, Michelle, Carles, Annaick, Moore, Richard, Mungall, Andrew J., Marra, Marco A., Jones, Steven J.M., Aparicio, Samuel, Hirst, Martin, Eaves, Connie J.

“…The normal adult human mammary gland is a continuous bilayered epithelial system. Bipotent and myoepithelial progenitors are prominent and unique components of…”
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Operational Tree Species Mapping in a Diverse Tropical Forest with Airborne Imaging Spectroscopy by Baldeck, Claire A, Asner, Gregory P, Martin, Robin E, Anderson, Christopher B, Knapp, David E, Kellner, James R, Wright, S Joseph

“…Remote identification and mapping of canopy tree species can contribute valuable information towards our understanding of ecosystem biodiversity and function…”
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Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression by Knapp, David J. H. F., Michaels, Yale S., Jamilly, Max, Ferry, Quentin R. V., Barbosa, Hector, Milne, Thomas A., Fulga, Tudor A.

“…Spatial/temporal control of Cas9 guide RNA expression could considerably expand the utility of CRISPR-based technologies. Current approaches based on tRNA…”
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Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice by Grants, Jennifer M., Wegrzyn, Joanna, Hui, Tony, O'Neill, Kieran, Shadbolt, Marion, Knapp, David J.H.F., Parker, Jeremy, Deng, Yu, Gopal, Aparna, Docking, T. Roderick, Fuller, Megan, Li, Jenny, Boldin, Mark, Eaves, Connie J., Hirst, Martin, Karsan, Aly

“…Aging is associated with significant changes in the hematopoietic system, including increased inflammation, impaired hematopoietic stem cell (HSC) function,…”
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Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs by O'Byrne, Sorcha, Elliott, Natalina, Rice, Siobhan, Buck, Gemma, Fordham, Nicholas, Garnett, Catherine, Godfrey, Laura, Crump, Nicholas T., Wright, Gary, Inglott, Sarah, Hua, Peng, Psaila, Bethan, Povinelli, Benjamin, Knapp, David J.H.F., Agraz-Doblas, Antonio, Bueno, Clara, Varela, Ignacio, Bennett, Phillip, Koohy, Hashem, Watt, Suzanne M., Karadimitris, Anastasios, Mead, Adam J., Ancliff, Phillip, Vyas, Paresh, Menendez, Pablo, Milne, Thomas A., Roberts, Irene, Roy, Anindita

“…Human lymphopoiesis is a dynamic lifelong process that starts in utero 6 weeks postconception. Although fetal B-lymphopoiesis remains poorly defined, it is key…”
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Forest canopy gap distributions in the southern Peruvian Amazon by Asner, Gregory P, Kellner, James R, Kennedy-Bowdoin, Ty, Knapp, David E, Anderson, Christopher, Martin, Roberta E

“…Canopy gaps express the time-integrated effects of tree failure and mortality as well as regrowth and succession in tropical forests. Quantifying the size and…”
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