Search Results - "David García Cruz"
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Kinesin-5/Eg5 is important for transport of CARTS from the trans-Golgi network to the cell surface
Published in The Journal of cell biology (22-07-2013)“…Here we report that the kinesin-5 motor Klp61F, which is known for its role in bipolar spindle formation in mitosis, is required for protein transport from the…”
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Correction: The Long Coiled-Coil Protein NECC2 Is Associated to Caveolae and MODULATES NGF/TrkA Signaling IN PC12 CELLS
Published in PloS one (12-09-2013)Get full text
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The long coiled-coil protein NECC2 is associated to caveolae and modulates NGF/TrkA signaling in PC12 cells [corrected]
Published in PloS one (06-09-2013)“…TrkA-mediated NGF signaling in PC12 cells has been shown to be compartimentalized in specialized microdomains of the plasma membrane, the caveolae, which are…”
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The Golgi-associated long coiled-coil protein NECC1 participates in the control of the regulated secretory pathway in PC12 cells
Published in Biochemical journal (15-04-2012)“…Golgi-associated long coiled-coil proteins, often referred to as golgins, are involved in the maintenance of the structural organization of the Golgi apparatus…”
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Reactive oxygen species triggers unconventional secretion of antioxidants and Acb1
Published in The Journal of cell biology (06-04-2020)“…Nutrient deprivation triggers the release of signal-sequence-lacking Acb1 and the antioxidant superoxide dismutase 1 (SOD1). We now report that secreted SOD1…”
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A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1
Published in The Journal of cell biology (04-09-2017)“…The nutrient starvation-specific unconventional secretion of Acb1 in requires ESCRT-I, -II, and -III and Grh1. In this study, we report that another signal…”
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Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export
Published in The EMBO journal (12-06-2013)“…The BAR (Bin/Amphiphysin/Rvs) domain proteins arfaptin1 and arfaptin2 are localized to the trans‐Golgi network (TGN) and, by virtue of their ability to sense…”
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Rab18 Inhibits Secretory Activity in Neuroendocrine Cells by Interacting with Secretory Granules
Published in Traffic (Copenhagen, Denmark) (01-07-2007)“…Rab proteins comprise a complex family of small GTPases involved in the regulation of intracellular membrane trafficking and reorganization. In this study, we…”
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Unconventional protein secretion triggered by nutrient starvation
Published in Seminars in cell & developmental biology (01-11-2018)“…It is usually assumed that eukaryotic cells secrete only proteins that contain a signal sequence for Sec61 mediated translocation into the lumen of endoplasmic…”
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Remodeling of secretory compartments creates CUPS during nutrient starvation
Published in The Journal of cell biology (22-12-2014)“…Upon starvation, Grh1, a peripheral membrane protein located at endoplasmic reticulum (ER) exit sites and early Golgi in Saccharomyces cerevisiae under growth…”
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La hipertensión arterial: un problema de salud internacional
Published in Revista médica electrónica (01-08-2017)“…En el mundo actual la hipertensión arterial una de las enfermedades más comunes que afectan la salud humana, siendo patología y factor de riesgo importante…”
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La hipertensión arterial: un problema de salud internacional
Published in Revista médica electrónica“…En el mundo actual la hipertensión arterial una de las enfermedades más comunes que afectan la salud humana, siendo patología y factor de riesgo importante…”
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Tras las huellas de Sherlock Holmes
Published in El Ciervo (01-10-2020)Get full text
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