Search Results - "David C. Harris"

Macrophages in kidney injury, inflammation, and fibrosis by Cao, Qi, Harris, David C H, Wang, Yiping

“…Macrophages are found in normal kidney and in increased numbers in diseased kidney, where they act as key players in renal injury, inflammation, and fibrosis…”
Get full text

Patient and Caregiver Priorities for Outcomes in Hemodialysis: An International Nominal Group Technique Study by Urquhart-Secord, Rachel, MPH, Craig, Jonathan C., PhD, Hemmelgarn, Brenda, PhD, Tam-Tham, Helen, MSc, Manns, Braden, PhD, Howell, Martin, PhD, Polkinghorne, Kevan R., PhD, Kerr, Peter G., PhD, Harris, David C., PhD, MBBS, Thompson, Stephanie, MD, Schick-Makaroff, Kara, PhD, Wheeler, David C., MD, van Biesen, Wim, PhD, Winkelmayer, Wolfgang C., MD, ScD, Johnson, David W., PhD, Howard, Kirsten, PhD, Evangelidis, Nicole, BSocSc, Tong, Allison, PhD

“…Background In the context of clinical research, investigators have historically selected the outcomes that they consider to be important, but these are often…”
Get full text

Macrophages in Renal Disease by YIPING WANG, HARRIS, David C. H

“…Macrophages have heterogeneous phenotypes as they exercise their twofold role in the development and recovery of renal diseases. Some subpopulations of…”
Get full text

Effects of Allopurinol on the Progression of Chronic Kidney Disease by Badve, Sunil V, Pascoe, Elaine M, Tiku, Anushree, Boudville, Neil, Brown, Fiona G, Cass, Alan, Clarke, Philip, Dalbeth, Nicola, Day, Richard O, de Zoysa, Janak R, Douglas, Bettina, Faull, Randall, Harris, David C, Hawley, Carmel M, Jones, Graham R.D, Kanellis, John, Palmer, Suetonia C, Perkovic, Vlado, Rangan, Gopala K, Reidlinger, Donna, Robison, Laura, Walker, Robert J, Walters, Giles, Johnson, David W

“…This randomized trial assessed whether urate-lowering treatment with allopurinol could attenuate eGFR decline in at-risk patients with stage 3 or 4 chronic…”
Get full text

Developing a Set of Core Outcomes for Trials in Hemodialysis: An International Delphi Survey by Evangelidis, Nicole, BSocSc, Tong, Allison, PhD, Manns, Braden, MD, MSc, Hemmelgarn, Brenda, MD, PhD, Wheeler, David C., MD, Tugwell, Peter, MD, Crowe, Sally, PGDip, Harris, Tess, Van Biesen, Wim, MD, PhD, Winkelmayer, Wolfgang C., MD, ScD, Sautenet, Benedicte, MD, PhD, O’Donoghue, Donal, MB, Tam-Tham, Helen, MSc, Youssouf, Sajeda, MD, Mandayam, Sreedhar, MD, PhD, Ju, Angela, BSc (Hons), Hawley, Carmel, MBBS, Pollock, Carol, PhD, Harris, David C., MD, MBBS, Johnson, David W., PhD, Rifkin, Dena E., MD, Tentori, Francesca, MD, MS, Agar, John, MBBS, Polkinghorne, Kevan R., PhD, Gallagher, Martin, PhD, Kerr, Peter G., PhD, McDonald, Stephen P., PhD, Howard, Kirsten, PhD, Howell, Martin, PhD, Craig, Jonathan C., PhD

“…Background Survival and quality of life for patients on hemodialysis therapy remain poor despite substantial research efforts. Existing trials often report…”
Get full text

A Randomized, Controlled Trial of Early versus Late Initiation of Dialysis by Cooper, Bruce A, Branley, Pauline, Bulfone, Liliana, Collins, John F, Craig, Jonathan C, Fraenkel, Margaret B, Harris, David C, Harris, Anthony, Johnson, David W, Kesselhut, Joan, Li, Jing Jing, Luxton, Grant, Pilmore, Andrew, Tiller, David J, Pollock, Carol A

“…In this study, adults with progressive chronic kidney disease and an estimated glomerular filtration rate between 10 and 15 ml per minute per 1.73 m 2 (stage V…”
Get full text

Adriamycin nephropathy: A model of focal segmental glomerulosclerosis by LEE, VINCENT WS, HARRIS, DAVID CH

“…ABSTRACT Adriamycin nephropathy (AN) is a rodent model of chronic kidney disease that has been studied extensively and has enabled a greater understanding of…”
Get full text

Pathogenic and protective role of macrophages in kidney disease by Cao, Qi, Wang, Yiping, Harris, David C H

“…Macrophages (MΦ) are located throughout kidney tissue, where they play important roles in homeostasis, surveillance, tolerance, and cytoprotection. MΦ are…”
Get more information

Ethical challenges in nephrology: a call for action by Martin, Dominique E., Harris, David C. H., Jha, Vivekanand, Segantini, Luca, Demme, Richard A., Le, Thu H., McCann, Laura, Sands, Jeff M., Vong, Gerard, Wolpe, Paul Root, Fontana, Monica, London, Gerard M., Vanderhaegen, Bert, Vanholder, Raymond

“…The American Society of Nephrology, the European Renal Association–European Dialysis and Transplant Association and the International Society of Nephrology…”
Get full text

An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis by Roediger, Ben, Lee, Quintin, Tikoo, Shweta, Cobbin, Joanna C.A., Henderson, James M., Jormakka, Mika, O’Rourke, Matthew B., Padula, Matthew P., Pinello, Natalia, Henry, Marisa, Wynne, Maria, Santagostino, Sara F., Brayton, Cory F., Rasmussen, Lorna, Lisowski, Leszek, Tay, Szun S., Harris, David C., Bertram, John F., Dowling, John P., Bertolino, Patrick, Lai, Jack H., Wu, Wengen, Bachovchin, William W., Wong, Justin J.-L., Gorrell, Mark D., Shaban, Babak, Holmes, Edward C., Jolly, Christopher J., Monette, Sébastien, Weninger, Wolfgang

“…The occurrence of a spontaneous nephropathy with intranuclear inclusions in laboratory mice has puzzled pathologists for over 4 decades, because its etiology…”
Get full text

The Role of Macrophages in Kidney Fibrosis by Wang, Xiaoling, Chen, Jianwei, Xu, Jun, Xie, Jun, Harris, David C H, Zheng, Guoping

“…The phenotypic heterogeneity and functional diversity of macrophages confer on them complexed roles in the development and progression of kidney diseases…”
Get full text

Effects of uric acid-lowering therapy on renal outcomes: a systematic review and meta-analysis by Bose, Bhadran, Badve, Sunil V, Hiremath, Swapnil S, Boudville, Neil, Brown, Fiona G, Cass, Alan, de Zoysa, Janak R, Fassett, Robert G, Faull, Randall, Harris, David C, Hawley, Carmel M, Kanellis, John, Palmer, Suetonia C, Perkovic, Vlado, Pascoe, Elaine M, Rangan, Gopala K, Walker, Robert J, Walters, Giles, Johnson, David W

“…Non-randomized studies suggest an association between serum uric acid levels and progression of chronic kidney disease (CKD). The aim of this systematic review…”
Get full text

IL-10/TGF-β-Modified Macrophages Induce Regulatory T Cells and Protect against Adriamycin Nephrosis by QI CAO, YIPING WANG, HARRIS, David C. H, DONG ZHENG, YAN SUN, YA WANG, LEE, Vincent W. S, GUOPING ZHENG, THIAN KUI TAN, INCE, Jon, ALEXANDER, Stephen I

“…IL-10/TGF-beta-modified macrophages, a subset of activated macrophages, produce anti-inflammatory cytokines, suggesting that they may protect against…”
Get full text

ENHANCE: a comparative prospective longitudinal study of cognitive outcomes after 3 years of hearing aid use in older adults by Sarant, Julia Z, Busby, Peter A, Schembri, Adrian J, Fowler, Christopher, Harris, David C

“…With an aging population, the prevalence of hearing loss and dementia are increasing rapidly. Hearing loss is currently considered the largest potentially…”
Get full text

Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial by Sagar, Priyanka S, Munt, Alexandra, Saravanabavan, Sayanthooran, Vahedi, Farnoosh Asghar, Elhindi, James, Nguyen, Beatrice, Chau, Katrina, Harris, David C, Lee, Vincent, Sud, Kamal, Wong, Nikki, Rangan, Gopala K

“…In autosomal dominant polycystic kidney disease (ADPKD) impaired nitric oxide (NO) synthesis, in part, contributes to early-onset hypertension. Beetroot juice…”
Get full text

Availability, Accessibility, and Quality of Conservative Kidney Management Worldwide by Lunney, Meaghan, Bello, Aminu K, Levin, Adeera, Tam-Tham, Helen, Thomas, Chandra, Osman, Mohamed A, Ye, Feng, Bellorin-Font, Ezequiel, Benghanem Gharbi, Mohammed, Ghnaimat, Mohammad, Htay, Htay, Cho, Yeoungjee, Jha, Vivekanand, Ossareh, Shahrzad, Rondeau, Eric, Sola, Laura, Tchokhonelidze, Irma, Tesar, Vladimir, Tungsanga, Kriang, Kazancioglu, Rumeyza Turan, Wang, Angela Yee-Moon, Yang, Chih-Wei, Zemchenkov, Alexander, Zhao, Ming-Hui, Jager, Kitty J, Jindal, Kailash K, Okpechi, Ikechi G, Brown, Edwina A, Brown, Mark, Tonelli, Marcello, Harris, David C, Johnson, David W, Caskey, Fergus J, Davison, Sara N

“…People with kidney failure typically receive KRT in the form of dialysis or transplantation. However, studies have suggested that not all patients with kidney…”
Get full text

Patients' Experiences and Perspectives of Living With CKD by Tong, Allison, PhD, Sainsbury, Peter, PhD, Chadban, Steven, PhD, Walker, Rowan G., PhD, Harris, David C., PhD, Carter, Stacy M., PhD, Hall, Bronwyn, MAAPD, Hawley, Carmel, MBBS, Craig, Jonathan C., PhD

“…Explicit incorporation of patients' values and preferences is important in health care decision making. However, there are few data about this topic for…”
Get full text

Rate of decline in residual kidney function pre and post peritoneal dialysis initiation: A post hoc analysis of the IDEAL study by Ethier, Isabelle, Cho, Yeoungjee, Hawley, Carmel, Pascoe, Elaine M, Viecelli, Andrea K, Campbell, Scott B, van Eps, Carolyn, Isbel, Nicole M, Cooper, Bruce A, Harris, David C, Pollock, Carol A, Wong, Muh Geot, Johnson, David W

“…Residual kidney function (RKF) is associated with improved survival and quality of life in dialysis patients. Previous studies have suggested that initiation…”
Get full text

Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells by Zhao, Ye, Qiao, Xi, Wang, Lihua, Tan, Tian Kui, Zhao, Hong, Zhang, Yun, Zhang, Jianlin, Rao, Padmashree, Cao, Qi, Wang, Yiping, Wang, Ya, Wang, Yuan Min, Lee, Vincent W S, Alexander, Stephen I, Harris, David C H, Zheng, Guoping

“…Endothelial-mesenchymal transition (EndoMT) is a major source of myofibroblast formation in kidney fibrosis. Our previous study showed a profibrotic role for…”
Get full text

Cost-Effectiveness of Initiating Dialysis Early: A Randomized Controlled Trial by Harris, Anthony, MA, MSc, Cooper, Bruce A., MBBS, MM(ClinEpi), PhD, FRACP, Li, Jing Jing, BPharm, BCom, Bulfone, Liliana, BPharm, MBA, GradCertHealthEco, Branley, Pauline, BMed, PhD, FRACP, Collins, John F., MBChB, Craig, Jonathan C., MBChB, DCH, MM (ClinEpi), PhD, Fraenkel, Margaret B., BM, BS, PhD, FRACP, Johnson, David W., MBBS, PhD, FRACP, PhD, Kesselhut, Joan, RN, Luxton, Grant, MBBS, FRACP, Pilmore, Andrew, BSc, DipSc, Rosevear, Martin, BA, BSc, Tiller, David J., AO, MBBS, FRACP, Pollock, Carol A., MBBS, PhD, FRACP, Harris, David C., MD, BS, FRACP

“…Background Planned early initiation of dialysis therapy based on estimated kidney function does not influence mortality and major comorbid conditions, but…”
Get full text