Search Results - "David, T.S"

Bat flight and zoonotic viruses by O'Shea, Thomas J, Cryan, Paul M, Cunningham, Andrew A, Fooks, Anthony R, Hayman, David T S, Luis, Angela D, Peel, Alison J, Plowright, Raina K, Wood, James L N

“…Bats are sources of high viral diversity and high-profile zoonotic viruses worldwide. Although apparently not pathogenic in their reservoir hosts, some viruses…”
Get full text

Reversal of epigenetic aging and immunosenescent trends in humans by Fahy, Gregory M., Brooke, Robert T., Watson, James P., Good, Zinaida, Vasanawala, Shreyas S., Maecker, Holden, Leipold, Michael D., Lin, David T. S., Kobor, Michael S., Horvath, Steve

“…Epigenetic “clocks” can now surpass chronological age in accuracy for estimating biological age. Here, we use four such age estimators to show that epigenetic…”
Get full text

Bats as Viral Reservoirs by Hayman, David T.S

“…Bats are hosts of a range of viruses, including ebolaviruses, and many important human viral infections, such as measles and mumps, may have their ancestry…”
Get full text

Enzymatic protein depalmitoylation by acyl protein thioesterases by Lin, David T S, Conibear, Elizabeth

“…Protein palmitoylation is a dynamic post-translational modification, where the 16-carbon fatty acid, palmitate, is added to cysteines of proteins to modulate…”
Get more information

Ebola virus antibodies in fruit bats, Ghana, West Africa by Hayman, David T S, Yu, Meng, Crameri, Gary, Wang, Lin-Fa, Suu-Ire, Richard, Wood, James L N, Cunningham, Andrew A

Get full text

Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents by Horvath, Steve, Stein, Dan J, Phillips, Nicole, Heany, Sarah J, Kobor, Michael S, Lin, David T.S, Myer, Landon, Zar, Heather J, Levine, Andrew J, Hoare, Jacqueline

“…OBJECTIVE:Recent studies demonstrate that infection with the HIV-1 is associated with accelerated aging effects in adults according to a highly accurate…”
Get full text

Regulation of somatic cell reprogramming through inducible mir-302 expression by Lin, Shi-Lung, Chang, Donald C, Lin, Chun-Hung, Ying, Shao-Yao, Leu, Davey, Wu, David T.S

“…Global demethylation is required for early zygote development to establish stem cell pluripotency, yet our findings reiterate this epigenetic reprogramming…”
Get full text

Bartonella bacteria in nature: Where does population variability end and a species start? by Kosoy, Michael, Hayman, David T.S., Chan, Kung-Sik

“…► Bartonella are emergent pathogens with a unique hemotropic parasitic strategy. ► Bartonella genetic diversity is great, particularly among rodent and bat…”
Get full text

Genomic Analysis of Salmonella enterica Serovar Typhimurium DT160 Associated with a 14-Year Outbreak, New Zealand, 1998-2012 by Bloomfield, Samuel J, Benschop, Jackie, Biggs, Patrick J, Marshall, Jonathan C, Hayman, David T S, Carter, Philip E, Midwinter, Anne C, Mather, Alison E, French, Nigel P

“…During 1998-2012, an extended outbreak of Salmonella enterica serovar Typhimurium definitive type 160 (DT160) affected >3,000 humans and killed wild birds in…”
Get full text

MicroRNA miR-302 Inhibits the Tumorigenecity of Human Pluripotent Stem Cells by Coordinate Suppression of the CDK2 and CDK4/6 Cell Cycle Pathways by LIN, Shi-Lung, CHANG, Donald C, YING, Shao-Yao, LEU, Davey, WU, David T. S

“…miR-302 is the major microRNA found in human embryonic stem cells and induced pluripotent stem cells, but its function has been unclear. In mice, there is…”
Get full text

Genetic susceptibility to asthma increases the vulnerability to indoor air pollution by Hüls, Anke, Vanker, Aneesa, Gray, Diane, Koen, Nastassja, MacIsaac, Julia L, Lin, David T S, Ramadori, Katia E, Sly, Peter D, Stein, Dan J, Kobor, Michael S, Zar, Heather J

“…Indoor air pollution and maternal smoking during pregnancy are associated with respiratory symptoms in infants, but little is known about the direct…”
Get full text

The Global Phylogeography of Lyssaviruses - Challenging the 'Out of Africa' Hypothesis by Hayman, David T S, Fooks, Anthony R, Marston, Denise A, Garcia-R, Juan C

“…Rabies virus kills tens of thousands of people globally each year, especially in resource-limited countries. Yet, there are genetically- and…”
Get full text

A Role of Oxytocin Receptor Gene Brain Tissue Expression Quantitative Trait Locus rs237895 in the Intergenerational Transmission of the Effects of Maternal Childhood Maltreatment by Toepfer, Philipp, O'Donnell, Kieran J., Entringer, Sonja, Heim, Christine M., Lin, David T.S., MacIsaac, Julia L., Kobor, Michael S., Meaney, Michael J., Provençal, Nadine, Binder, Elisabeth B., Wadhwa, Pathik D., Buss, Claudia

“…Women exposed to childhood maltreatment (CM) are more likely to exhibit insensitive parenting, which may have consequences for their offspring’s development…”
Get full text

Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness by Toepfer, Philipp, O’Donnell, Kieran J., Entringer, Sonja, Garg, Elika, Heim, Christine M., Lin, David T.S., MacIsaac, Julia L., Kobor, Michael S., Meaney, Michael J., Provençal, Nadine, Binder, Elisabeth B., Wadhwa, Pathik D., Buss, Claudia

“…•Oxytocin gene (OXT) promoter DNA methylation is dynamically changing throughout pregnancy.•Dynamic OXT promotor DNA methylation during pregnancy predicts…”
Get full text

Body mass and hibernation microclimate may predict bat susceptibility to white‐nose syndrome by Haase, Catherine G., Fuller, Nathan W., Dzal, Yvonne A., Hranac, C. Reed, Hayman, David T. S., Lausen, Cori L., Silas, Kirk A., Olson, Sarah H., Plowright, Raina K.

“…In multihost disease systems, differences in mortality between species may reflect variation in host physiology, morphology, and behavior. In systems where the…”
Get full text

Developing One Health surveillance systems by Hayman, David T.S., Adisasmito, Wiku B., Almuhairi, Salama, Behravesh, Casey Barton, Bilivogui, Pépé, Bukachi, Salome A., Casas, Natalia, Becerra, Natalia Cediel, Charron, Dominique F., Chaudhary, Abhishek, Ciacci Zanella, Janice R., Cunningham, Andrew A., Dar, Osman, Debnath, Nitish, Dungu, Baptiste, Farag, Elmoubasher, Gao, George F., Khaitsa, Margaret, Machalaba, Catherine, Mackenzie, John S., Markotter, Wanda, Mettenleiter, Thomas C., Morand, Serge, Smolenskiy, Vyacheslav, Zhou, Lei, Koopmans, Marion

“…The health of humans, domestic and wild animals, plants, and the environment are inter-dependent. Global anthropogenic change is a key driver of disease…”
Get full text

Genomic and phenotypic comparison of two Salmonella Typhimurium strains responsible for consecutive salmonellosis outbreaks in New Zealand by Bloomfield, Samuel J., Benschop, Jackie, Midwinter, Anne C., Biggs, Patrick J., Marshall, Jonathan C., Hayman, David T.S., Carter, Philip E., Price-Carter, Marian, Toombs-Ruane, Leah, Gray, Holly, Burgess, Sara, French, Nigel P.

“…•DT160 and DT56v shared an estimated date of common ancestor between 1769 and 1821.•DT160 replicated at a faster rate than DT56v in vitro.•Neither DT160 nor…”
Get full text

Micromanipulation System for Isolating a Single Cryptosporidium Oocyst by Penny, Hamish, Hayman, David T S, Avci, Ebubekir

“…In this paper, an integrated system for contact micromanipulation of oocysts is presented. The system integrates five actuators and a partially automated…”
Get full text

Use of cross-reactive serological assays for detecting novel pathogens in wildlife: Assessing an appropriate cutoff for henipavirus assays in African bats by Peel, Alison J., McKinley, Trevelyan J., Baker, Kate S., Barr, Jennifer A., Crameri, Gary, Hayman, David T.S., Feng, Yan-Ru, Broder, Christopher C., Wang, Lin-Fa, Cunningham, Andrew A., Wood, James L.N.

“…•We assess microsphere binding assay cutoffs in the absence of gold standard assays.•Binding assay output on a continuous scale was visualised in frequency…”
Get full text

Steps towards operationalizing One Health approaches by Pepin, Kim M., Carlisle, Keith, Anderson, Dean, Baker, Michael G., Chipman, Richard B., Benschop, Jackie, French, Nigel P., Greenhalgh, Suzie, McDougall, Scott, Muellner, Petra, Murphy, Emil, O'Neale, Dion R.J., Plank, Michael J., Hayman, David T.S.

“…One Health recognizes the health of humans, agriculture, wildlife, and the environment are interrelated. The concept has been embraced by international health…”
Get full text