Search Results - "David, J.P."
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1
The Obstetric Origins of Health for a Lifetime
Published in Clinical obstetrics and gynecology (01-09-2013)“…There is a new “developmental” model for the origins of a wide range of chronic diseases. Under this model the causes to be identified are linked to normal…”
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2
Copper-Catalyzed Trifluoromethylation of Alkyl Bromides
Published in Journal of the American Chemical Society (01-05-2019)“…Copper oxidative addition into organohalides is a challenging two-electron process. In contrast, formal oxidative addition of copper to Csp2 carbon–bromine…”
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3
Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells
Published in Cell metabolism (05-12-2012)“…Metabolic reprogramming of cancer cells provides energy and multiple intermediates critical for cell growth. Hypoxia in tumors represents a hostile environment…”
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Remote sensing of dryland ecosystem structure and function: Progress, challenges, and opportunities
Published in Remote sensing of environment (01-11-2019)“…Drylands make up roughly 40% of the Earth's land surface, and billions of people depend on services provided by these critically important ecosystems. Despite…”
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Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis
Published in Nanomedicine (01-12-2011)“…Abstract Cellular microvesicles and nanovesicles (exosomes) are involved in many disease processes and have major potential as biomarkers. However,…”
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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
Published in Nature medicine (01-01-2010)“…Mutations in NOD2—a bacterial sensor in dendritic cells—and mutations in genes related to autophagosome function have been linked to Crohn's disease. Alison…”
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Trajectories of Growth among Children Who Have Coronary Events as Adults
Published in The New England journal of medicine (27-10-2005)“…Low birth weight is a risk factor for the subsequent development of coronary disease. The effect of childhood growth on coronary risk was evaluated in a cohort…”
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Division and Transmission: Malaria Parasite Development in the Mosquito
Published in Annual review of microbiology (08-09-2022)“…The malaria parasite life cycle alternates between two hosts: a vertebrate and the female Anopheles mosquito vector. Cell division, proliferation, and invasion…”
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Pre-Eclampsia Is Associated With Increased Risk of Stroke in the Adult Offspring : The Helsinki Birth Cohort Study
Published in Stroke (1970) (01-04-2009)“…Women who develop pre-eclampsia in pregnancy are at increased risk of cardiovascular disease. The offspring from pregnancies complicated by pre-eclampsia have…”
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10
Boys live dangerously in the womb
Published in American journal of human biology (01-05-2010)“…The growth of every human fetus is constrained by the limited capacity of the mother and placenta to deliver nutrients to it. At birth, boys tend to be longer…”
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Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma
Published in Journal of controlled release (10-05-2016)“…Asthma is a worldwide health problem. Activated T cells (ATCs) in the lung, particularly T helper 2 cells (Th2), are strongly associated with inducing airway…”
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12
tree-ring perspective on the terrestrial carbon cycle
Published in Oecologia (01-10-2014)“…Tree-ring records can provide valuable information to advance our understanding of contemporary terrestrial carbon cycling and to reconstruct key metrics in…”
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13
Longer growing seasons lead to less carbon sequestration by a subalpine forest
Published in Global change biology (01-02-2010)“…As global temperatures increase, the potential for longer growing seasons to enhance the terrestrial carbon sink has been proposed as a mechanism to reduce the…”
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14
Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome
Published in American journal of human genetics (01-12-2016)“…Uncombable hair syndrome (UHS), also known as “spun glass hair syndrome,” “pili trianguli et canaliculi,” or “cheveux incoiffables” is a rare anomaly of the…”
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Preterm Birth--A Risk Factor for Type 2 Diabetes?: The Helsinki Birth Cohort Study
Published in Diabetes care (01-12-2010)“…OBJECTIVE: The association between low birth weight and type 2 diabetes is well established. We studied whether preterm birth carries a similar risk. RESEARCH…”
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Recapitulation of erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities
Published in Haematologica (Roma) (01-11-2021)“…The investigation of inherited disorders of erythropoiesis has elucidated many of the principles underlying the production of normal red blood cells and how…”
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Relation of Serial Changes in Childhood Body-Mass Index to Impaired Glucose Tolerance in Young Adulthood
Published in The New England journal of medicine (26-02-2004)“…This study from Delhi, India, assessed 1442 men and women 26 to 32 years of age who had been evaluated at birth and throughout childhood in a prospective,…”
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An actor-based approach to understanding radical right viral tweets in the UK
Published in Journal of policing, intelligence and counter terrorism (03-04-2023)“…Radical right actors routinely use social media to spread highly divisive, disruptive, and anti-democratic messages. Assessing and countering such content is…”
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Fetal programming of coronary heart disease
Published in Trends in Endocrinology & Metabolism (01-11-2002)“…People who develop coronary heart disease grow differently from other people both in utero and during childhood. Slow growth during fetal life and infancy is…”
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Effect of household bleach on the structure of the sporocyst wall of Toxoplasma gondii
Published in Parasite (Paris) (2021)“…Toxoplasma gondii oocysts are responsible for food- and water-borne infections in humans worldwide. They are resistant to common chemical disinfectants,…”
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