Search Results - "David, J S"
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The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc
Published in Nature immunology (01-07-2019)“…Natural killer (NK) cells are critical mediators of host immunity to pathogens. Here, we demonstrate that the endoplasmic reticulum stress sensor…”
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Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients
Published in British journal of anaesthesia : BJA (01-06-2008)“…Blood loss and uncontrollable bleeding are major factors affecting survival in trauma patients. Because treatment with antifibrinolytic drugs may be effective,…”
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Plasmon‐Promoted Electrochemical Oxygen Evolution Catalysis from Gold Decorated MnO2 Nanosheets under Green Light
Published in Advanced functional materials (01-08-2018)“…The oxygen evolution reaction (OER) is of great importance for renewable energy conversion and storage; however, the intrinsic process is sluggish and suffers…”
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Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan
Published in Nature (London) (14-04-2011)“…Healthy proteins for a longer life The amyloid-binding histological dye thioflavin T (ThT) is known to slow protein aggregation in vitro . Experiments in…”
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Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites
Published in Science signaling (29-05-2018)“…Fibrillar collagens of the extracellular matrix are critical for tissue structure and physiology; however, excessive or abnormal deposition of collagens is a…”
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Xylem function and growth rate interact to determine recovery rates after exposure to extreme water deficit
Published in The New phytologist (01-10-2010)“…Motivated by the urgent need to understand how water stress-induced embolism limits the survival and recovery of plants during drought, the linkage between…”
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Ecology of planktonic ciliates in a changing world: Concepts, methods, and challenges
Published in The Journal of eukaryotic microbiology (01-09-2022)“…Plankton ecologists ultimately focus on forecasting, both applied and environmental outcomes. We review how appreciating planktonic ciliates has become central…”
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The human dimension of fire regimes on Earth
Published in Journal of biogeography (01-12-2011)“…Humans and their ancestors are unique in being a fire-making species, but 'natural' (i.e. independent of humans) fires have an ancient, geological history on…”
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Structural basis of homo- and heterotrimerization of collagen I
Published in Nature communications (10-03-2017)“…Fibrillar collagen molecules are synthesized as precursors, procollagens, with large propeptide extensions. While a homotrimeric form (three α1 chains) has…”
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Nanoparticle Metrology of Silicates Using Time-Resolved Multiplexed Dye Fluorescence Anisotropy, Small Angle X-ray Scattering, and Molecular Dynamics Simulations
Published in Materials (01-04-2024)“…We investigate the nanometrology of sub-nanometre particle sizes in industrially manufactured sodium silicate liquors at high pH using time-resolved…”
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Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1)
Published in Scientific reports (01-09-2022)“…Sizzled (Szl) is both a secreted frizzled related protein (sFRP) and a naturally occurring inhibitor of the zinc metalloproteinase bone morphogenetic protein-1…”
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Predicting Marine Phytoplankton Maximum Growth Rates from Temperature: Improving on the Eppley Curve Using Quantile Regression
Published in Limnology and oceanography (01-03-2008)“…The Eppley curve describes an exponential function that defines the maximum attainable daily growth rate of marine phytoplankton as a function of temperature…”
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Phenotypic analysis of extracellular vesicles: a review on the applications of fluorescence
Published in Journal of extracellular vesicles (01-01-2020)“…Extracellular vesicles (EVs) have numerous potential applications in the field of healthcare and diagnostics, and research into their biological functions is…”
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Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength
Published in Proceedings of the National Academy of Sciences - PNAS (27-08-2013)“…Type I fibrillar collagen is the most abundant protein in the human body, crucial for the formation and strength of bones, skin, and tendon. Proteolytic…”
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Experimental and numerical investigation of the flow in a cylindrical cavity with an unsteady rotating lid
Published in Acta mechanica (01-03-2022)“…In this paper, we analyse the flow in a cylindrical cavity of aspect ratio H / R = 2, with a top lid rotating with a sinusoidal time-varying speed. The…”
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An evidence-based framework for predicting the impact of differing autotroph-heterotroph thermal sensitivities on consumer–prey dynamics
Published in The ISME Journal (01-07-2016)“…Increased temperature accelerates vital rates, influencing microbial population and wider ecosystem dynamics, for example, the predicted increases in…”
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Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling
Published in PLoS pathogens (01-10-2017)“…Bacillus anthracis, the causative agent of anthrax, secretes lethal toxin that down-regulates immune functions. Translocation of B. anthracis across mucosal…”
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Gold nanorods for fluorescence lifetime imaging in biology
Published in Journal of Biomedical Optics (01-03-2010)“…Two-photon luminescence (TPL) from gold nanorods shows considerable potential in biological imaging. We study the imaging of gold nanorods in Madin-Darby…”
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Population collapse of a Gondwanan conifer follows the loss of Indigenous fire regimes in a northern Australian savanna
Published in Scientific reports (31-05-2022)“…Colonialism has disrupted Indigenous socioecological systems around the globe, including those supported by intentional landscape burning. Because most…”
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The interactive effects of ammonia and microcystin on life-history traits of the cladoceran Daphnia magna: synergistic or antagonistic?
Published in PloS one (05-03-2012)“…The occurrence of Microcystis blooms is a worldwide concern that has caused numerous adverse effects on water quality and lake ecology. Elevated ammonia and…”
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