Optimally Controlled Diabetes and Its Influence on Neonatal Outcomes at a Level II Center: A Study on Infants Born to Diabetic Mothers

: We investigated the effect of optimal maternal glycemic control on neonatal outcomes among infants born to mothers with diabetes. : In this prospective study, we assessed 88 eligible mothers admitted to the obstetrics department for pregnancy evaluation. Our analysis included 46 infants born to di...

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Published in:	Medicina (Kaunas, Lithuania) Vol. 59; no. 10; p. 1768
Main Authors:	Muntean, Mihai, Prelipcean, Irina, Racean, Maria-Andreea, Cucerea, Manuela, Fagarasan, Amalia, David, Carmen Tamara, Marginean, Claudiu, Suciu, Laura Mihaela
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01-10-2023 MDPI
Subjects:	antenatal Body mass index Cesarean section Cesarean Section - adverse effects Childbirth & labor Congenital diseases Congenital heart disease Diabetes therapy Diabetes, Gestational Female Genetic disorders Gestational age Gestational diabetes Glucose Health care Humans Hypoglycemia Infant Infant, Newborn Infants (Newborn) infants of diabetic mothers Insulin resistance Intensive Care Units, Neonatal Light therapy Maternal & child health Mothers Neonatal intensive care neonatal outcomes Neonatology Obstetrics optimally controlled diabetes Pregnancy Prospective Studies Respiratory tract diseases Type 2 diabetes Ultrasonic imaging Weight control Womens health Romania antenatal neonatal outcomes optimally controlled diabetes infants of diabetic mothers
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Summary:	: We investigated the effect of optimal maternal glycemic control on neonatal outcomes among infants born to mothers with diabetes. : In this prospective study, we assessed 88 eligible mothers admitted to the obstetrics department for pregnancy evaluation. Our analysis included 46 infants born to diabetic mothers (IDMs) and 138 infants born to unaffected mothers, all admitted to the Level II Neonatal Intensive Care Unit (NICU). : Mothers affected by diabetes were generally older and exhibited a higher body mass index (BMI) and a greater number of gestations, although parity did not differ significantly. Cesarean section emerged as the most frequently chosen mode of delivery. A significantly higher proportion of infants in the affected group presented with respiratory disease (3% vs. 19.5%), which required NICU admission (4.3% vs. 23.9%), phototherapy (18.1% vs. 43.5%), and had congenital heart defects or myocardial hypertrophy (15.2% and 26% vs. 3% and 4.3%) compared to matched controls ( < 0.05). : This study underscores the persistence of adverse neonatal outcomes in IDMs, even when maternal glycemic control is optimized. It calls for further investigation into potential interventions and strategies aimed at enhancing neonatal outcomes in this population.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1648-9144 1010-660X 1648-9144
DOI:	10.3390/medicina59101768