Search Results - "David, C"

Mitochondrial Dynamics and Its Involvement in Disease by Chan, David C

“…The dynamic properties of mitochondria-including their fusion, fission, and degradation-are critical for their optimal function in energy generation. The…”
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Phylogenomics reveals rapid, simultaneous diversification of three major clades of Gondwanan frogs at the Cretaceous–Paleogene boundary by Feng, Yan-Jie, Blackburn, David C., Liang, Dan, Hillis, David M., Wake, David B., Cannatella, David C., Zhang, Peng

“…Frogs (Anura) are one of the most diverse groups of vertebrates and comprise nearly 90% of living amphibian species. Their worldwide distribution and diverse…”
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Dapagliflozin in Patients with Chronic Kidney Disease by Heerspink, Hiddo J.L, Stefánsson, Bergur V, Correa-Rotter, Ricardo, Chertow, Glenn M, Greene, Tom, Hou, Fan-Fan, Mann, Johannes F.E, McMurray, John J.V, Lindberg, Magnus, Rossing, Peter, Sjöström, C. David, Toto, Roberto D, Langkilde, Anna-Maria, Wheeler, David C

“…In this trial, patients with CKD (with or without type 2 diabetes) were randomly assigned to receive dapagliflozin or placebo. The primary composite outcome —…”
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Effects of Dapagliflozin in Stage 4 Chronic Kidney Disease by Chertow, Glenn M, Vart, Priya, Jongs, Niels, Toto, Robert D, Gorriz, Jose Luis, Hou, Fan Fan, McMurray, John J V, Correa-Rotter, Ricardo, Rossing, Peter, Sjöström, C David, Stefánsson, Bergur V, Langkilde, Anna Maria, Wheeler, David C, Heerspink, Hiddo J L

“…In the Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney Disease (DAPA-CKD) randomized, placebo-controlled trial, the sodium-glucose…”
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Vaping-Induced Acute Lung Injury by Christiani, David C

“…A number of environmental agents are known to cause acute or subacute inhalation injury to the lung parenchyma. Indeed, emergency response guidelines for…”
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On the Prospects for a (Deep) Learning Health Care System by Naylor, C. David

“…In 1976, Maxmen predicted that artificial intelligence (AI) in the 21st century would usher in "the post-physician era," with health care provided by…”
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Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health by Chan, David C

“…Mitochondria are dynamic organelles that continually undergo fusion and fission. These opposing processes work in concert to maintain the shape, size, and…”
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Emerging importance of satellite glia in nervous system function and dysfunction by Hanani, Menachem, Spray, David C.

“…Satellite glial cells (SGCs) closely envelop cell bodies of neurons in sensory, sympathetic and parasympathetic ganglia. This unique organization is not found…”
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Overview of Castleman disease by Dispenzieri, Angela, Fajgenbaum, David C.

“…Castleman disease (CD) describes a group of at least 4 disorders that share a spectrum of characteristic histopathological features but have a wide range of…”
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Misunderstandings about Q and 'Cochran's Q test' in meta-analysis by Hoaglin, David C.

“…Many meta‐analyses report using ‘Cochran's Q test' to assess heterogeneity of effect‐size estimates from the individual studies. Some authors cite work by…”
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Metabolic regulation of mitochondrial dynamics by Mishra, Prashant, Chan, David C

“…Mitochondria are renowned for their central bioenergetic role in eukaryotic cells, where they act as powerhouses to generate adenosine triphosphate from…”
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The molecular hallmarks of epigenetic control by Allis, C. David, Jenuwein, Thomas

“…Over the past few decades, epigenetics has evolved from a collection of curious biological phenomena to a functionally dissected research field. In this…”
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Nursing Home Care in Crisis in the Wake of COVID-19 by Grabowski, David C, Mor, Vincent

“…This Viewpoint discusses the long-standing deficiencies in nursing home financing and organization made worse by the spread of coronavirus disease 2019…”
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The gender-equality paradox in science, technology, engineering, and mathematics education by Stoet, Gijsbert, Geary, David C

“…The underrepresentation of girls and women in science, technology, engineering, and mathematics (STEM) fields is a continual concern for social scientists and…”
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The puzzle of high temperature superconductivity in layered iron pnictides and chalcogenides by Johnston, David C.

“…The response of the worldwide scientific community to the discovery in 2008 of superconductivity at T c  = 26 K in the Fe-based compound LaFeAsO 1−x F x has…”
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Mechanisms of Autophagosome Biogenesis by Rubinsztein, David C., Shpilka, Tomer, Elazar, Zvulun

“…Autophagy is a unique membrane trafficking process whereby newly formed membranes, termed phagophores, engulf parts of the cytoplasm leading to the production…”
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Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease by Fajgenbaum, David C.

“…Castleman disease (CD) describes a heterogeneous group of hematologic disorders that share characteristic lymph node histopathology. Patients of all ages…”
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Site-selective Suzuki-Miyaura coupling of heteroaryl halides - understanding the trends for pharmaceutically important classes by Almond-Thynne, Joshua, Blakemore, David C, Pryde, David C, Spivey, Alan C

“…Suzuki-Miyaura cross-coupling reactions of heteroaryl polyhalides with aryl boronates are surveyed. Drawing on data from literature sources as well as bespoke…”
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Mitochondrial Dynamics in Regulating the Unique Phenotypes of Cancer and Stem Cells by Chen, Hsiuchen, Chan, David C.

“…Cancer and stem cells appear to share a common metabolic profile that is characterized by high utilization of glucose through aerobic glycolysis. In the…”
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Mitochondrial dynamics and inheritance during cell division, development and disease by Mishra, Prashant, Chan, David C.

“…Key Points Mitochondria are organelles with key roles in cellular metabolism. They have unique cellular dynamics to ensure their proper distribution to…”
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