Search Results - "David, Brian P."

Non-electrophilic NRF2 activators promote wound healing in human keratinocytes and diabetic mice and demonstrate selective downstream gene targeting by Barakat, May, Han, Chen, Chen, Lin, David, Brian P., Shi, Junhe, Xu, Angela, Skowron, Kornelia J., Johnson, Tatum, Woods, Reginald A., Ankireddy, Aparna, Reddy, Sekhar P., Moore, Terry W., DiPietro, Luisa A.

“…The transcription factor NRF2 plays an important role in many biological processes and is a promising therapeutic target for many disease states. NRF2 is…”
Get full text

Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors by Richardson, Benjamin G, Jain, Atul D, Potteti, Haranatha R, Lazzara, Phillip R, David, Brian P, Tamatam, Chandra R, Choma, Ewelina, Skowron, Kornelia, Dye, Katherine, Siddiqui, Zamia, Wang, Yue-Ting, Krunic, Aleksej, Reddy, Sekhar P, Moore, Terry W

“…Activators of nuclear factor-erythroid 2-related factor 2 (NRF2) could lead to promising therapeutics for prevention and treatment of oxidative stress and…”
Get full text

Isoquinoline Kelch-like ECH-Associated Protein 1‑Nuclear Factor (Erythroid-Derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability by Lazzara, Phillip R, David, Brian P, Ankireddy, Aparna, Richardson, Benjamin G, Dye, Katherine, Ratia, Kiira M, Reddy, Sekhar P, Moore, Terry W

“…Pharmacological activation of NRF2 (nuclear factor erythroid 2-related factor 2) arises from blocking the interaction of NRF2 with its negative regulator,…”
Get full text

Steroid receptor/coactivator binding inhibitors: An update by Skowron, Kornelia J., Booker, Kenneth, Cheng, Changfeng, Creed, Simone, David, Brian P., Lazzara, Phillip R., Lian, Amy, Siddiqui, Zamia, Speltz, Thomas E., Moore, Terry W.

“…The purpose of this review is to highlight recent developments in small molecules and peptides that block the binding of coactivators to steroid receptors…”
Get full text

Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors by Lazzara, Phillip R, Jain, Atul D, Maldonado, Amanda C, Richardson, Benjamin, Skowron, Kornelia J, David, Brian P, Siddiqui, Zamia, Ratia, Kiira M, Moore, Terry W

“…The oxidative stress response, gated by the protein–protein interaction of KEAP1 and NRF2, has garnered significant interest in the past decade. Misregulation…”
Get full text

Using Tumor Explants for Imaging Mass Spectrometry Visualization of Unlabeled Peptides and Small Molecules by David, Brian P., Dubrovskyi, Oleksii, Speltz, Thomas E., Wolff, Jeremy J., Frasor, Jonna, Sanchez, Laura M., Moore, Terry W.

“…Matrix assisted laser desorption ionization time-of-flight (MALDI-TOF) imaging mass spectrometry has emerged as a powerful, label-free technique to visualize…”
Get full text

Extraction of palladium(II) and platinum(IV) from a chloride medium by some diamine and monoamine extractants dissolved in 5% isodecanol-benzene by Tait, Brian K. & Shillington, David P.

Get full text

Extraction of palladium(II) and platinum(IV) from a chloride medium by some diamine and monoamine extractants dissolved in 5% isodecanol-benzene by Tait, Brian K. & Shillington, David P.

Get full text