Search Results - "Daventure, Victoria"

The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice by Bou-Jaoudeh, Melissa, Delignat, Sandrine, Daventure, Victoria, Astermark, Jan, Lévesque, Hervé, Dimitrov, Jordan D, Deligne, Claire, Proulle, Valérie, Lacroix-Desmazes, Sébastien

“…Neutralizing anti-factor VIII (FVIII) antibodies, known as FVIII inhibitors, represent a major drawback of replacement therapy in persons with congenital…”
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IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies by Leborgne, Christian, Barbon, Elena, Alexander, Jeffrey M., Hanby, Hayley, Delignat, Sandrine, Cohen, Daniel M., Collaud, Fanny, Muraleetharan, Saghana, Lupo, Dan, Silverberg, Joseph, Huang, Karen, van Wittengerghe, Laetitia, Marolleau, Béatrice, Miranda, Adeline, Fabiano, Anna, Daventure, Victoria, Beck, Heena, Anguela, Xavier M., Ronzitti, Giuseppe, Armour, Sean M., Lacroix-Desmazes, Sebastien, Mingozzi, Federico

“…Neutralizing antibodies to adeno-associated virus (AAV) vectors are highly prevalent in humans 1 , 2 , and block liver transduction 3 – 5 and vector…”
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Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance by Mimoun, Angelina, Delignat, Sandrine, Peyron, Ivan, Daventure, Victoria, Lecerf, Maxime, Dimitrov, Jordan D, Kaveri, Srinivas V, Bayry, Jagadeesh, Lacroix-Desmazes, Sébastien

“…In humans, maternal IgGs are transferred to the fetus from the second trimester of pregnancy onwards. The transplacental delivery of maternal IgG is mediated…”
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Aromatic Guanylhydrazones for the Control of Heme-Induced Antibody Polyreactivity by Božinović, Nina, Ajdačić, Vladimir, Lazic, Jelena, Lecerf, Maxime, Daventure, Victoria, Nikodinovic-Runic, Jasmina, Opsenica, Igor M, Dimitrov, Jordan D

“…In a healthy immune repertoire, there exists a fraction of polyreactive antibodies that can bind to a variety of unrelated self- and foreign antigens. Apart…”
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IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies by Leborgne, Christian, Barbon, Elena, Alexander, Jeffrey, Hanby, Hayley, Delignat, Sandrine, Cohen, Daniel, Collaud, Fanny, Muraleetharan, Saghana, Lupo, Dan, Silverberg, Joseph, Huang, Karen, van Wittengerghe, Laetitia, Marolleau, Béatrice, Miranda, Adeline, Fabiano, Anna, Daventure, Victoria, Beck, Heena, Anguela, Xavier, Ronzitti, Giuseppe, Armour, Sean, Lacroix-Desmazes, Sebastien, Mingozzi, Federico

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V Region of IgG Controls the Molecular Properties of the Binding Site for Neonatal Fc Receptor by Rossini, Sofia, Noé, Rémi, Daventure, Victoria, Lecerf, Maxime, Justesen, Sune, Dimitrov, Jordan D

“…Neonatal Fc receptor (FcRn) has a key role in the homeostasis of IgG. Despite its physiological and clinical importance, the interaction of IgG and FcRn…”
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High factor VIII concentrations interfere with glycoprotein VI-mediated platelet activation in vitro by Sekar, Rohini, Mimoun, Angelina, Bou-Jaoudeh, Melissa, Loyau, Stéphane, Delignat, Sandrine, Daventure, Victoria, Bonilla, Perrine, Bhale, Aishwarya Sudam, Venkataraman, Krishnan, Rayes, Julie, Boulaftali, Yacine, Jandrot-Perrus, Martine, Proulle, Valérie, Lacroix-Desmazes, Sébastien

“…The recruitment of activated factor VIII (FVIII) at the surface of activated platelets is a key step toward the burst of thrombin and fibrin generation during…”
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The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice by Bou-Jaoudeh, Melissa, Delignat, Sandrine, Daventure, Victoria, Astermark, Jan, Lévesque, Hervé, Dimitrov, Jordan D, Deligne, Claire, Proulle, Valérie, Lacroix-Desmazes, Sébastien

“…Neutralizing anti-factor VIII (FVIII) antibodies, known as FVIII inhibitors, represent a major drawback of replacement therapy in persons with congenital…”
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High FVIII concentrations interfere with GPVI-mediated platelet activation in vitro by Sekar, Rohini, Mimoun, Angelina, Bou-Jaoudeh, Melissa, Loyau, Stéphane, Delignat, Sandrine, Daventure, Victoria, Bonilla, Perrine, Bahle, Aishwarya Sudam, Venkataraman, Krishnan, Rayes, Julie, Boulaftali, Yacine, Jandrot-Perrus, Martine, Proulle, Valérie, Lacroix-Desmazes, Sébastien

“…The recruitment of activated FVIII at the surface of activated platelets is a key step towards the burst of thrombin and fibrin generation during thrombus…”
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Transplacental delivery of therapeutic proteins by engineered IgG: a step towards perinatal replacement therapy by Mimoun, Angelina, Bou Jaoudeh, Melissa, Delignat, Sandrine, Daventure, Victoria, Reyes Ruiz, Alejandra, Lecerf, Maxime, Azam, Aurélien, Noe, Remi, Peyron, Ivan, Christophe, Olivier, Lenting, Peter, Proulle, Valérie, Mcintosh, Jenny, Nathwani, Amit, Dimitrov, Jordan, Denis, Cécile, Lacroix-Desmazes, Sébastien

“…Background: Transplacental delivery of maternal IgG provides humoral protection during the first months of life until the newborn’s immune system reaches…”
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Imlifidase, a new option to optimize the management of patients with hemophilia A on emicizumab by Bou-Jaoudeh, Melissa, Mimoun, Angelina, Delignat, Sandrine, Peyron, Ivan, Capdevila, Ladislas, Daventure, Victoria, Deligne, Claire, Dimitrov, Jordan D., Christophe, Olivier D., Denis, Cécile V., Lenting, Peter J., Proulle, Valérie, Lacroix-Desmazes, Sébastien

“…Emicizumab is a bispecific, chimeric, humanized immunoglobulin G (IgG)4 that mimics the procoagulant activity of factor (F) VIII (FVIII). Its long half-life…”
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Transplacental delivery of therapeutic proteins by engineered immunoglobulin G: a step toward perinatal replacement therapy by Mimoun, Angelina, Bou-Jaoudeh, Melissa, Delignat, Sandrine, Daventure, Victoria, Reyes Ruiz, Alejandra, Lecerf, Maxime, Azam, Aurélien, Noe, Remi, Peyron, Ivan, Christophe, Olivier D., Lenting, Peter J., Proulle, Valérie, McIntosh, Jenny, Nathwani, Amit C., Dimitrov, Jordan D., Denis, Cécile V., Lacroix-Desmazes, Sébastien

“…Transplacental delivery of maternal immunoglobulin G (IgG) provides humoral protection during the first months of life until the newborn’s immune system…”
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Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance by Mimoun, Angelina, Delignat, Sandrine, Peyron, Ivan, Daventure, Victoria, Lecerf, Maxime, Dimitrov, Jordan, Kaveri, Srinivas, Bayry, Jagadeesh, Lacroix-Desmazes, Sébastien

“…Background: Transplacental delivery of maternal IgG provides humoral protection duringthe first months of life until the newborn’s immune system reaches…”
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IdeS, a new option to optimize the management of patients with hemophilia A on emicizumab by Bou-Jaoudeh, Melissa, Mimoun, Angelina, Delignat, Sandrine, Peyron, Ivan, Capdevila, Ladislas, Daventure, Victoria, Deligne, Claire, Dimitrov, Jordan D, Christophe, Olivier D, Denis, Cécile V, Lenting, Peter J, Proulle, Valérie, Lacroix-Desmazes, Sébastien

“…Emicizumab is a bispecific chimeric humanized IgG4 that mimics the procoagulant activity of factor VIII (FVIII). Its long half-life and subcutaneous injection…”
Get full text