Search Results - "Davenport Huyer, Locke"

Advanced Strategies for Modulation of the Material–Macrophage Interface by Davenport Huyer, Locke, Pascual‐Gil, Simon, Wang, Yufeng, Mandla, Serena, Yee, Bess, Radisic, Milica

“…Biomaterials are becoming increasingly crucial for healthcare solutions, with extensive use in the field of tissue engineering and drug delivery. After…”
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A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling by Zhao, Yimu, Rafatian, Naimeh, Feric, Nicole T., Cox, Brian J., Aschar-Sobbi, Roozbeh, Wang, Erika Yan, Aggarwal, Praful, Zhang, Boyang, Conant, Genevieve, Ronaldson-Bouchard, Kacey, Pahnke, Aric, Protze, Stephanie, Lee, Jee Hoon, Davenport Huyer, Locke, Jekic, Danica, Wickeler, Anastasia, Naguib, Hani E., Keller, Gordon M., Vunjak-Novakovic, Gordana, Broeckel, Ulrich, Backx, Peter H., Radisic, Milica

“…Tissue engineering using cardiomyocytes derived from human pluripotent stem cells holds a promise to revolutionize drug discovery, but only if limitations…”
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Flexible shape-memory scaffold for minimally invasive delivery of functional tissues by Montgomery, Miles, Ahadian, Samad, Davenport Huyer, Locke, Lo Rito, Mauro, Civitarese, Robert A., Vanderlaan, Rachel D., Wu, Jun, Reis, Lewis A., Momen, Abdul, Akbari, Saeed, Pahnke, Aric, Li, Ren-Ke, Caldarone, Christopher A., Radisic, Milica

“…Despite great progress in engineering functional tissues for organ repair, including the heart, an invasive surgical approach is still required for their…”
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Recapitulating Pancreatic Tumor Microenvironment through Synergistic Use of Patient Organoids and Organ‐on‐a‐Chip Vasculature by Lai, Benjamin Fook Lun, Lu, Rick Xing Ze, Hu, Yangshuo, Davenport Huyer, Locke, Dou, Wenkun, Wang, Erika Yan, Radulovich, Nikolina, Tsao, Ming Sound, Sun, Yu, Radisic, Milica

“…Tumor progression relies on the interaction between neoplastic epithelial cells and their surrounding stromal partners. This cell cross‐talk affects stromal…”
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Microfabrication of AngioChip, a biodegradable polymer scaffold with microfluidic vasculature by Zhang, Boyang, Lai, Benjamin Fook Lun, Xie, Ruoxiao, Davenport Huyer, Locke, Montgomery, Miles, Radisic, Milica

“…Microengineered biomimetic systems for organ-on-a-chip or tissue engineering purposes often fail as a result of an inability to recapitulate the in vivo…”
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Organ‐On‐A‐Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies by Ahadian, Samad, Civitarese, Robert, Bannerman, Dawn, Mohammadi, Mohammad Hossein, Lu, Rick, Wang, Erika, Davenport‐Huyer, Locke, Lai, Ben, Zhang, Boyang, Zhao, Yimu, Mandla, Serena, Korolj, Anastasia, Radisic, Milica

“…Significant advances in biomaterials, stem cell biology, and microscale technologies have enabled the fabrication of biologically relevant tissues and organs…”
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Review: Multimodal bioactive material approaches for wound healing by Mandla, Serena, Davenport Huyer, Locke, Radisic, Milica

“…Wound healing is a highly complex process of tissue repair that relies on the synergistic effect of a number of different cells, cytokines, enzymes, and growth…”
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Biowire Model of Interstitial and Focal Cardiac Fibrosis by Wang, Erika Yan, Rafatian, Naimeh, Zhao, Yimu, Lee, Angela, Lai, Benjamin Fook Lun, Lu, Rick Xingze, Jekic, Danica, Davenport Huyer, Locke, Knee-Walden, Ericka J, Bhattacharya, Shoumo, Backx, Peter H, Radisic, Milica

“…Myocardial fibrosis is a severe global health problem due to its prevalence in all forms of cardiac diseases and direct role in causing heart failure. The…”
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One‐Pot Synthesis of Unsaturated Polyester Bioelastomer with Controllable Material Curing for Microscale Designs by Davenport Huyer, Locke, Bannerman, A. Dawn, Wang, Yufeng, Savoji, Houman, Knee‐Walden, Ericka J., Brissenden, Amanda, Yee, Bess, Shoaib, Mohammad, Bobicki, Erin, Amsden, Brian G., Radisic, Milica

“…Synthetic polyester elastomeric constructs have become increasingly important for a range of healthcare applications, due to tunable soft elastic properties…”
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Itaconate and citrate releasing polymer attenuates foreign body response in biofabricated cardiac patches by Bannerman, Dawn, Pascual-Gil, Simon, Campbell, Scott, Jiang, Richard, Wu, Qinghua, Okhovatian, Sargol, Wagner, Karl T., Montgomery, Miles, Laflamme, Michael A., Davenport Huyer, Locke, Radisic, Milica

“…Application of cardiac patches to the heart surface can be undertaken to provide support and facilitate regeneration of the damaged cardiac tissue following…”
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Organ‐On‐A‐Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies by Ahadian, Samad, Civitarese, Robert, Bannerman, Dawn, Mohammadi, Mohammad Hossein, Lu, Rick, Wang, Erika, Davenport‐Huyer, Locke, Lai, Ben, Zhang, Boyang, Zhao, Yimu, Mandla, Serena, Korolj, Anastasia, Radisic, Milica

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Enhancing senior high school student engagement and academic performance using an inclusive and scalable inquiry-based program by Davenport Huyer, Locke, Callaghan, Neal I., Dicks, Sara, Scherer, Edward, Shukalyuk, Andrey I., Jou, Margaret, Kilkenny, Dawn M.

“…The multi-disciplinary nature of science, technology, engineering, and math (STEM) careers often renders difficulty for high school students navigating from…”
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Harnessing conserved signaling and metabolic pathways to enhance the maturation of functional engineered tissues by Callaghan, Neal I., Durland, Lauren J., Ireland, Ronald G., Santerre, J. Paul, Simmons, Craig A., Davenport Huyer, Locke

“…The development of induced-pluripotent stem cell (iPSC)-derived cell types offers promise for basic science, drug testing, disease modeling, personalized…”
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Moldable elastomeric polyester-carbon nanotube scaffolds for cardiac tissue engineering by Ahadian, Samad, Davenport Huyer, Locke, Estili, Mehdi, Yee, Bess, Smith, Nathaniel, Xu, Zhensong, Sun, Yu, Radisic, Milica

“…[Display omitted] Polymer biomaterials are used to construct scaffolds in tissue engineering applications to assist in mechanical support, organization, and…”
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Elastomeric Polyesters in Cardiovascular Tissue Engineering and Organs-on-a-Chip by Okhovatian, Sargol, Shakeri, Amid, Davenport Huyer, Locke, Radisic, Milica

“…Cardiovascular tissue constructs provide unique design requirements due to their functional responses to substrate mechanical properties and cyclic stretching…”
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A well plate–based multiplexed platform for incorporation of organoids into an organ-on-a-chip system with a perfusable vasculature by Lai, Benjamin Fook Lun, Lu, Rick Xing Ze, Davenport Huyer, Locke, Kakinoki, Sachiro, Yazbeck, Joshua, Wang, Erika Yan, Wu, Qinghua, Zhang, Boyang, Radisic, Milica

“…Owing to their high spatiotemporal precision and adaptability to different host cells, organ-on-a-chip systems are showing great promise in drug discovery,…”
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The role of Wnt regulation in heart development, cardiac repair and disease: A tissue engineering perspective by Pahnke, Aric, Conant, Genna, Huyer, Locke Davenport, Zhao, Yimu, Feric, Nicole, Radisic, Milica

“…Wingless-related integration site (Wnt) signaling has proven to be a fundamental mechanism in cardiovascular development as well as disease. Understanding its…”
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InVADE: Integrated Vasculature for Assessing Dynamic Events by Lai, Benjamin Fook Lun, Huyer, Locke Davenport, Lu, Rick Xing Ze, Drecun, Stasja, Radisic, Milica, Zhang, Boyang

“…Drug screening with simplified 2D cell culture and relevant animal testing fail to predict clinical outcomes. With the rising cost of drug development,…”
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Degradation of poly(5-hydroxy-trimethylene carbonate) in aqueous environments by Chen, Fei, Qi, Ronghui, Huyer, Locke Davenport, Amsden, Brian G.

“…Poly(5-hydroxy-trimethylene carbonate) (PHTMC) was synthesized through ring-opening polymerization of 5-benzyloxy trimethylene carbonate followed by…”
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Highly Elastic and Moldable Polyester Biomaterial for Cardiac Tissue Engineering Applications by Davenport Huyer, Locke, Zhang, Boyang, Korolj, Anastasia, Montgomery, Miles, Drecun, Stasja, Conant, Genevieve, Zhao, Yimu, Reis, Lewis, Radisic, Milica

“…Polyester biomaterials are used in tissue engineering as scaffolds for implantation of tissues developed in vitro. An ideal biodegradable elastomer for cardiac…”
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