Search Results - "Davaadelger, Batzaya"

BRCA1 mutation influences progesterone response in human benign mammary organoids by Davaadelger, Batzaya, Choi, Mi-Ran, Singhal, Hari, Clare, Susan E, Khan, Seema A, Kim, J Julie

“…Women, who carry a germline BRCA1 gene mutation, have a markedly increased risk of developing breast cancer during their lifetime. While BRCA1 carriers…”
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The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis by Davaadelger, Batzaya, Perez, Ricardo E., Zhou, Yalu, Duan, Lei, Gitelis, Steven, Maki, Carl G.

“…Nutlin-3a is a small molecule MDM2 antagonist and potent activator of wild-type p53. Nutlin-3a disrupts MDM2 binding to p53, thus increasing p53 levels and…”
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Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor by Davaadelger, Batzaya, Duan, Lei, Perez, Ricardo E, Gitelis, Steven, Maki, Carl G

“…The insulin-like growth factor-1 receptor (IGF-1R) signaling pathway is aberrantly activated in multiple cancers and can promote proliferation and chemotherapy…”
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Novel roles for p53 in the genesis and targeting of tetraploid cancer cells by Davaadelger, Batzaya, Shen, Hong, Maki, Carl G

“…Tetraploid (4N) cells are considered important in cancer because they can display increased tumorigenicity, resistance to conventional therapies, and are…”
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Two 4N cell-cycle arrests contribute to cisplatin-resistance by Shen, Hong, Perez, Ricardo E, Davaadelger, Batzaya, Maki, Carl G

“…Cisplatin is a platinum-based drug that is used for the treatment of a wide-variety of primary human cancers. However, the therapeutic efficacy of cisplatin is…”
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Abstract PS19-09: Alternative splicing events from progesterone exposure differ based on BRCA1 mutation status by Cottone, Gannon, Davaadelger, Batzaya, Yadav, Shivangi, Kim, J Julie, Khan, Seema A., Clare, Susan

“…Background: Progesterone (P) and progestin are instrumental in the breast cancer risk associated with reproductive hormones. Progesterone receptor (PR)…”
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Abstract 1812: Mechanism of telapristone acetate (CDB4124) on progesterone receptor action in breast cancer cells by Davaadelger, Batzaya, Khan, Seema A., Kim, J Julie

“…Progesterone is a steroid hormone that plays an important role in the breast. Progesterone exerts its action through binding to Progesterone Receptor (PR), a…”
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Generation of Multicellular Human Primary Endometrial Organoids by Murphy, Alina R, Wiwatpanit, Teerawat, Lu, Zhenxiao, Davaadelger, Batzaya, Kim, J Julie

“…The human endometrium is one of the most hormonally responsive tissues in the body and is essential for the establishment of pregnancy. This tissue can also…”
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Mechanism of Telapristone Acetate (CDB4124) on Progesterone Receptor Action in Breast Cancer Cells by Davaadelger, Batzaya, Murphy, Alina R, Clare, Susan E, Lee, Oukseub, Khan, Seema A, Kim, J Julie

“…Progesterone is a steroid hormone that plays an important role in the breast. Progesterone exerts its action through binding to progesterone receptor (PR), a…”
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SUN-010 BRCA1 Mutation Influences Progesterone Response in Human Benign Mammospheres by Davaadelger, Batzaya, Khan, Seema, Kim, Julie

“…Women, who carry a germline mutation in the breast cancer-associated gene 1 (BRCA1) have an increased risk (60-85%) of developing breast cancer during their…”
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p53-regulated autophagy is controlled by glycolysis and determines cell fate by Duan, Lei, Perez, Ricardo E, Davaadelger, Batzaya, Dedkova, Elena N, Blatter, Lothar A, Maki, Carl G

“…The tumor suppressor p53 regulates downstream targets that determine cell fate. Canonical p53 functions include inducing apoptosis, growth arrest, and…”
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Alteration in Aromatase and Estrogen Receptor Target Gene Expression in Human Benign Mammary Tissue After Bariatric Surgery by Davaadelger, Batzaya, Rangan, Manish, Singhal, Hari, Muzzio, Miguel, Pincus, Jennifer Lynn, Blanco, Luis, Greene, Geoffrey L, Kim, Julie, Kulkarni, Swati

“…Background: Over 30% of US adults are obese (body mass index (BMI) of ≥ 30 kg/m2). Obesity is considered a significant and modifiable risk factor for ER+…”
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Isolation and characterization of an interactive culture of two Paenibacillus species with moderately thermophilic desulfurization ability by Wang, Jia, Davaadelger, Batzaya, Salazar, Joelle K, Butler, Robert R., III, Pombert, Jean-François, Kilbane, John J, Stark, Benjamin C

“…OBJECTIVE: To isolate and characterize novel thermophilic bacteria capable of biodesulfurization of petroleum. RESULTS: A culture containing two Paenibacillus…”
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Novel Roles for P53 in the Genesis and Targeting of Tetraploid Cancer Cells: e110844 by Davaadelger, Batzaya, Shen, Hong, Maki, Carl G

“…Tetraploid (4N) cells are considered important in cancer because they can display increased tumorigenicity, resistance to conventional therapies, and are…”
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Two 4N Cell-Cycle Arrests Contribute to Cisplatin-Resistance. e59848 by Shen, Hong, Perez, Ricardo E, Davaadelger, Batzaya, Maki, Carl G

“…Cisplatin is a platinum-based drug that is used for the treatment of a wide-variety of primary human cancers. However, the therapeutic efficacy of cisplatin is…”
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The role of p53, ploidy and IGF-1R/AKT/mTORC1 pathway in cisplatin resistance by Davaadelger, Batzaya

“…p53 is a transcription factor and key regulator of cancer chemotherapy responses. p53 is inactive and expressed at low levels in most cells due to a short…”
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The role of p53, ploidy and IGF-1R/AKT/mTORC1 pathway in cisplatin resistance by Davaadelger, Batzaya

“…p53 is a transcription factor and key regulator of cancer chemotherapy responses. p53 is inactive and expressed at low levels in most cells due to a short…”
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