Search Results - "Dausse, Eric"

A combinatorial approach to the repertoire of RNA kissing motifs; towards multiplex detection by switching hairpin aptamers by Durand, Guillaume, Dausse, Eric, Goux, Emma, Fiore, Emmanuelle, Peyrin, Eric, Ravelet, Corinne, Toulmé, Jean-Jacques

“…Loop-loop (also known as kissing) interactions between RNA hairpins are involved in several mechanisms in both prokaryotes and eukaryotes such as the…”
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Riboswitches Based on Kissing Complexes for the Detection of Small Ligands by Durand, Guillaume, Lisi, Samuele, Ravelet, Corinne, Dausse, Eric, Peyrin, Eric, Toulmé, Jean-Jacques

“…Biosensors derived from aptamers were designed for which folding into a hairpin shape is triggered by binding of the cognate ligand. These aptamers (termed…”
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Aptamer selection by direct microfluidic recovery and surface plasmon resonance evaluation by Dausse, Eric, Barré, Aurélien, Aimé, Ahissan, Groppi, Alexis, Rico, Alain, Ainali, Chrysanthi, Salgado, Gilmar, Palau, William, Daguerre, Emilie, Nikolski, Macha, Toulmé, Jean-Jacques, Di Primo, Carmelo

“…A surface plasmon resonance (SPR)-based SELEX approach has been used to raise RNA aptamers against a structured RNA, derived from XBP1 pre-mRNA, that folds as…”
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Triggering nucleic acid nanostructure assembly by conditional kissing interactions by Azéma, Laurent, Bonnet-Salomon, Servane, Endo, Masayuki, Takeuchi, Yosuke, Durand, Guillaume, Emura, Tomoko, Hidaka, Kumi, Dausse, Eric, Sugiyama, Hiroshi, Toulmé, Jean-Jacques

“…Abstract Nucleic acids are biomolecules of amazing versatility. Beyond their function for information storage they can be used for building nano-objects. We…”
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Aptamers: a new class of oligonucleotides in the drug discovery pipeline? by Dausse, Eric, Da Rocha Gomes, Sonia, Toulmé, Jean-Jacques

“…Aptamers are oligonucleotides identified in a randomly synthesized library containing up to 1015 different molecules that fold into defined three-dimensional…”
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An improved design of the kissing complex-based aptasensor for the detection of adenosine by Goux, Emma, Lisi, Samuele, Ravelet, Corinne, Durand, Guillaume, Fiore, Emmanuelle, Dausse, Eric, Toulmé, Jean-Jacques, Peyrin, Eric

“…We very recently reported a novel aptamer biosensing concept based on a dual recognition mechanism originating from the small target-induced formation of a…”
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Single-molecule observations of RNA-RNA kissing interactions in a DNA nanostructure by Takeuchi, Yosuke, Endo, Masayuki, Suzuki, Yuki, Hidaka, Kumi, Durand, Guillaume, Dausse, Eric, Toulmé, Jean-Jacques, Sugiyama, Hiroshi

“…RNA molecules uniquely form a complex through specific hairpin loops, called a kissing complex. The kissing complex is widely investigated and used for the…”
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Nucleic acids targeted to drugs: SELEX against a quadruplex ligand by Renaud de la Faverie, Amandine, Hamon, Florian, Di Primo, Carmelo, Largy, Eric, Dausse, Eric, Delaurière, Laurence, Landras-Guetta, Corinne, Toulmé, Jean-Jacques, Teulade-Fichou, Marie-Paule, Mergny, Jean-Louis

“…A number of small molecules demonstrate selective recognition of G-quadruplexes and are able to stabilize their formation. In this work, we performed the…”
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In Vitro Selection of RNA Aptamers Derived from a Genomic Human Library against the TAR RNA Element of HIV-1 by Watrin, Marguerite, Von Pelchrzim, Frederike, Dausse, Eric, Schroeder, Renée, Toulmé, Jean-Jacques

“…The transactivating responsive (TAR) element is a RNA hairpin located in the 5′ untranslated region of HIV-1 mRNA. It is essential for full-length…”
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HAPIscreen, a method for high-throughput aptamer identification by Dausse, Eric, Taouji, Saïd, Evadé, Laetitia, Di Primo, Carmelo, Chevet, Eric, Toulmé, Jean-Jacques

“…Aptamers are oligonucleotides displaying specific binding properties for a predetermined target. They are selected from libraries of randomly synthesized…”
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Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA by Löscher, Marlies, Schosserer, Markus, Dausse, Eric, Lee, Kiseok, Ajuh, Paul, Grillari-Voglauer, Regina, Lamond, Angus I, Toulmé, Jean-Jacques, Grillari, Johannes

“…Originally the novel protein Blom7α was identified as novel pre-mRNA splicing factor that interacts with SNEV(Prp19/Pso4), an essential protein involved in…”
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Determinants of apical loop–internal loop RNA–RNA interactions involving the HCV IRES by Da Rocha Gomes, Sonia, Dausse, Eric, Toulmé, Jean-Jacques

“…Domain II of the hepatitis C virus internal ribosome entry site is a major RNA structure involved in the viral mRNA translation. It comprises four different…”
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Apical Loop−Internal Loop Interactions:  A New RNA−RNA Recognition Motif Identified through in Vitro Selection against RNA Hairpins of the Hepatitis C Virus mRNA by Aldaz-Carroll, Lydia, Tallet, Béatrice, Dausse, Eric, Yurchenko, Ludmila, Toulmé, Jean-Jacques

“…We performed in vitro selection of oligoribonucleotides in order to identify high-affinity motifs recognizing RNA hairpins located at the 3‘ end (SL1) and at…”
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A malachite green light-up aptasensor for the detection of theophylline by Sett, Arghya, Zara, Lorena, Dausse, Eric, Toulmé, Jean-Jacques

“…Biosensors are of interest for the quantitative detection of small molecules (metabolites, drugs and contaminants for instance). To this end, fluorescence is a…”
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Engineering Light-Up Aptamers for the Detection of RNA Hairpins through Kissing Interaction by Sett, Arghya, Zara, Lorena, Dausse, Eric, Toulmé, Jean-Jacques

“…Aptasensors are biosensors that include aptamers for detecting a target of interest. We engineered signaling aptasensors for the detection of RNA hairpins from…”
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ELAKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform by Chovelon, Benoit, Durand, Guillaume, Dausse, Eric, Toulmé, Jean-Jacques, Faure, Patrice, Peyrin, Eric, Ravelet, Corinne

“…We report herein a novel sandwich-type enzyme-linked assay for the “signal-on” colorimetric detection of small molecules. The approach (referred to as…”
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Electrostatics Explains the Position-Dependent Effect of GU Wobble Base Pairs on the Affinity of RNA Kissing Complexes by Abi-Ghanem, Josephine, Rabin, Clémence, Porrini, Massimiliano, Dausse, Eric, Toulme, Jean-Jacques, Gabelica, Valérie

“…In the RNA realm, non-Watson-Crick base pairs are abundant and can affect both the RNA 3D structure and its function. Here, we investigated the formation of…”
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DNA Aptamers Selected Against the HIV-1trans-Activation-responsive RNA Element Form RNA-DNA Kissing Complexes by Boiziau, Claudine, Dausse, Eric, Yurchenko, Ludmila, Toulmé, Jean-Jacques

“…In vitro selection was performed in a DNA library, made of oligonucleotides with a 30-nucleotide random sequence, to identify ligands of the human…”
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(99m)Tc-MAG3-aptamer for imaging human tumors associated with high level of matrix metalloprotease-9 by Da Rocha Gomes, Sonia, Miguel, Julie, Azéma, Laurent, Eimer, Sandrine, Ries, Colette, Dausse, Eric, Loiseau, Hugues, Allard, Michèle, Toulmé, Jean-Jacques

“…The human matrix metalloprotease 9 (hMMP-9) is involved in many physiological processes such as tissue remodeling. Its overexpression in tumors promotes the…”
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Aptamers in Bordeaux 2017: An exceptional “millésime” by Toulmé, Jean-Jacques, Azéma, Laurent, Darfeuille, Fabien, Dausse, Eric, Durand, Guillaume, Paurelle, Olivier

“…About 150 participants attended the symposium organised at the Palais de la Bourse in Bordeaux, France on September 22–23, 2017. Thirty speakers from all over…”
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