Search Results - "Daunt, Carmel"

Helminth infection driven gastrointestinal hypermotility is independent of eosinophils and mediated by alterations in smooth muscle instead of enteric neurons by Wang, Haozhe, Barry, Kristian, Zaini, Aidil, Coakley, Gillian, Moyat, Mati, Daunt, Carmel P, Wickramasinghe, Lakshanie C, Azzoni, Rossana, Chatzis, Roxanne, Yumnam, Bibek, Camberis, Mali, Le Gros, Graham, Perdijk, Olaf, Foong, Jaime P P, Bornstein, Joel C, Marsland, Benjamin J, Harris, Nicola L

“…Intestinal helminth infection triggers a type 2 immune response that promotes a 'weep-and sweep' response characterised by increased mucus secretion and…”
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Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation by Fischer, Karla C., Daunt, Carmel P., Tremblay, Cédric S., Dias, Sheila, Vince, James E., Jabbour, Anissa M.

“…The IκB kinase complex, consisting of IKK1, IKK2 and the regulatory subunit NEMO, is required for NF-κB signalling following the activation of several cell…”
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Early life inter-kingdom interactions shape the immunological environment of the airways by Pattaroni, Céline, Macowan, Matthew, Chatzis, Roxanne, Daunt, Carmel, Custovic, Adnan, Shields, Michael D, Power, Ultan F, Grigg, Jonathan, Roberts, Graham, Ghazal, Peter, Schwarze, Jürgen, Gore, Mindy, Turner, Steve, Bush, Andrew, Saglani, Sejal, Lloyd, Clare M, Marsland, Benjamin J

“…There is increasing evidence that the airway microbiome plays a key role in the establishment of respiratory health by interacting with the developing immune…”
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p53-Dependent transcriptional responses to interleukin-3 signaling by Jabbour, Anissa M, Gordon, Lavinia, Daunt, Carmel P, Green, Benjamin D, Kok, Chung H, D'Andrea, Richard, Ekert, Paul G

“…p53 is critical in the normal response to a variety of cellular stresses including DNA damage and loss of p53 function is a common feature of many cancers. In…”
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Signal Regulatory Protein Molecules Are Differentially Expressed by CD8- Dendritic Cells by Lahoud, Mireille H, Proietto, Anna I, Gartlan, Kate H, Kitsoulis, Susie, Curtis, Joan, Wettenhall, James, Sofi, Mariam, Daunt, Carmel, O'Keeffe, Meredith, Caminschi, Irina, Satterley, Keith, Rizzitelli, Alexandra, Schnorrer, Petra, Hinohara, Atsushi, Yamaguchi, Yasunori, Wu, Li, Smyth, Gordon, Handman, Emanuela, Shortman, Ken, Wright, Mark D

“…A normalized subtracted gene expression library was generated from freshly isolated mouse dendritic cells (DC) of all subtypes, then used to construct cDNA…”
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Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation by Jabbour, Anissa M., Daunt, Carmel P., Green, Benjamin D., Vogel, Sandra, Gordon, Lavinia, Lee, Rachel S., Silke, Natasha, Pearson, Richard B., Vandenberg, Cassandra J., Kelly, Priscilla N., Nutt, Stephen L., Strasser, Andreas, Borner, Christoph, Ekert, Paul G.

“…Loss of p53-dependent apoptosis contributes to the development of hematologic malignancies and failure to respond to treatment. Proapoptotic Bcl-2 family…”
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Differential response of young and aged Virtual Memory CD8 T (TVM) cells to helminth-induced Th-2 cytokines by Hussain, Tabinda, Nguyen, Angela, Daunt, Carmel, Thiele, Daniel, Smith, Tiffany, Harris, Nicola, Quinn, Kylie, La Gruta, Nicole

“…TVM cells are antigen-naïve, semi-differentiated CD8 T cells that develop in response to common γ (γc) chain cytokines, like IL-15 and IL-4. TVM cells respond…”
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Helminth Infection-Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice by Hussain, Tabinda, Nguyen, Angela, Daunt, Carmel, Thiele, Daniel, Pang, Ee Shan, Li, Jasmine, Zaini, Aidil, O'Keeffe, Meredith, Zaph, Colby, Harris, Nicola L, Quinn, Kylie M, La Gruta, Nicole L

“…CD8 virtual memory T (TVM) cells are Ag-naive CD8 T cells that have undergone partial differentiation in response to common γ-chain cytokines, particularly…”
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Deep multiomic profiling reveals molecular signatures that underpin preschool wheeze and asthma by Macowan, Matthew, Pattaroni, Céline, Bonner, Katie, Chatzis, Roxanne, Daunt, Carmel, Gore, Mindy, Custovic, Adnan, Shields, Michael D., Power, Ultan F., Grigg, Jonathan, Roberts, Graham, Ghazal, Peter, Schwarze, Jürgen, Turner, Steve, Bush, Andrew, Saglani, Sejal, Lloyd, Clare M., Marsland, Benjamin J.

“…Wheezing in childhood is prevalent, with over one-half of all children experiencing at least 1 episode by age 6. The pathophysiology of wheeze, especially why…”
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Cytokine signalling in haematopoietic cells by Fischer, Karla, Masouras, Dimitra, Daunt, Carmel, Dias, Sheila, Ekert, Paul, Strasser, Andreas, Vaux, David, Jabbour, Anissa

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Deep Multi-Omic Profiling Reveals Molecular Signatures that Underpin Preschool Wheeze and Asthma by Macowan, Matthew, Pattaroni, Céline, Bonner, Katie, Chatzis, Roxanne, Daunt, Carmel, Gore, Mindy, Custovic, Adnan, Shields, Michael D, Power, Ultan F, Grigg, Jonathan, Roberts, Graham, Ghazal, Peter, Schwarze, Jürgen, Turner, Steve, Bush, Andrew, Saglani, Sejal, Lloyd, Clare M, Marsland, Benjamin J

“…Wheezing in childhood is prevalent, with over half of all children experiencing at least one episode by age six. The pathophysiology of wheeze, especially why…”
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Signal Regulatory Protein Molecules Are Differentially Expressed by CD8 super(-) Dendritic Cells by Lahoud, Mireille H, Proietto, Anna I, Gartlan, Kate H, Kitsoulis, Susie, Curtis, Joan, Wettenhall, James, Sofi, Mariam, Daunt, Carmel, O'Keeffe, Meredith, Caminschi, Irina, Satterley, Keith, Rizzitelli, Alexandra, Schnorrer, Petra, Hinohara, Atsushi, Yamaguchi, Yasunori, Wu, Li, Smyth, Gordon, Handman, Emanuela, Shortman, Ken, Wright, Mark D

“…A normalized subtracted gene expression library was generated from freshly isolated mouse dendritic cells (DC) of all subtypes, then used to construct cDNA…”
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