Search Results - "Daulhac, L"
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Magnesium attenuates chronic hypersensitivity and spinal cord NMDA receptor phosphorylation in a rat model of diabetic neuropathic pain
Published in The Journal of physiology (01-11-2010)“…Neuropathic pain is a common diabetic complication affecting 8–16% of diabetic patients. It is characterized by aberrant symptoms of spontaneous and…”
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Endocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesia
Published in Pain (Amsterdam) (30-09-2008)“…Acetaminophen is the most used analgesic/antipyretic drug. Its unclear mechanism of action could rely on cyclooxygenase inhibition, NO synthesis blockade or…”
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Memantine, a promising drug for the prevention of neuropathic pain in rat
Published in European journal of pharmacology (05-12-2013)“…N-methyl-d-aspartate (NMDA) receptor antagonists are used for post-surgery neuropathic pain but severe side-effects limit their clinical use. Memantine, when…”
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Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptors
Published in The Journal of biological chemistry (16-07-1999)“…We have analyzed in Chinese hamster ovary cells the upstream mediators by which the G protein-coupled receptor, gastrin/CCKB, activates the…”
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Acetaminophen recruits spinal p42/p44 MAPKs and GH/IGF-1 receptors to produce analgesia via the serotonergic system
Published in Molecular pharmacology (01-02-2007)“…The mechanism of action of acetaminophen is currently widely discussed. Direct inhibition of cyclooxygenase isoforms remains the commonly advanced hypothesis…”
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Gastrin-induced DNA synthesis requires p38-MAPK activation via PKC/Ca(2+) and Src-dependent mechanisms
Published in FEBS letters (04-05-2001)“…We present evidence that gastrin, binding to a G protein-coupled receptor, activates the p38-mitogen-activated protein kinase (MAPK) pathway. Blockage of…”
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Gastrin‐induced DNA synthesis requires p38‐MAPK activation via PKC/Ca2+ and Src‐dependent mechanisms
Published in FEBS letters (04-05-2001)“…We present evidence that gastrin, binding to a G protein‐coupled receptor, activates the p38‐mitogen‐activated protein kinase (MAPK) pathway. Blockage of…”
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Gastrin-induced DNA synthesis requires p38-MAPK activation via PKC/Ca super(2+) and Src-dependent mechanisms
Published in FEBS letters (04-05-2001)“…We present evidence that gastrin, binding to a G protein-coupled receptor, activates the p38-mitogen-activated protein kinase (MAPK) pathway. Blockage of…”
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Ca2+ and protein kinase C-dependent mechanisms involved in gastrin-induced Shc/Grb2 complex formation and P44-mitogen-activated protein kinase activation
Published in Biochemical journal (15-07-1997)“…The proliferative effects of gastrin on normal and neoplastic gastro-intestinal tissues have been shown to be mediated by the gastrin/CCKB (G/CCKB)…”
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Wortmannin-Sensitive Activation of p70S6-Kinase and MAP-Kinase by the G Protein-Coupled Receptor, G/CCKB
Published in Biochemical and biophysical research communications (08-09-1997)“…The gastrin/CCKB(G/CCKB) G protein-coupled receptor has been shown to mediate the proliferative effects of gastrin on normal and neoplastic gastro-intestinal…”
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Gastrin stimulates the formation of a P60-cSRC/P125-FAK complex upstream of the PI 3-kinase signaling pathway
Published in Gastroenterology (New York, N.Y. 1943) (15-04-1998)Get full text
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Ca super(2+) and protein kinase C-dependent mechanisms involved in gastrin-induced Shc/Grb2 complex formation and p44-mitogen-activated protein kinase activation
Published in Biochemical journal (01-07-1997)“…The proliferative effects of gastrin on normal and neoplastic gastro-intestinal tissues have been shown to be mediated by the gastrin/CCK sub(B) (G/CCK sub(B))…”
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Gastrin stimulates the formation of a p60Src/p125FAK complex upstream of the phosphatidylinositol 3‐kinase signaling pathway
Published in FEBS letters (26-02-1999)“…The molecular events whereby gastrin occupancy of G/CCKB receptors leads to phosphatidylinositol (PI) 3‐kinase activation have been examined. We report here…”
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