Search Results - "Daube, S S"
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A genetic circuit on a single DNA molecule as an autonomous dissipative nanodevice
Published in Nature communications (29-01-2024)“…Realizing genetic circuits on single DNA molecules as self-encoded dissipative nanodevices is a major step toward miniaturization of autonomous biological…”
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From deterministic to fuzzy decision-making in artificial cells
Published in Nature communications (06-11-2020)“…Building autonomous artificial cells capable of homeostasis requires regulatory networks to gather information and make decisions that take time and cost…”
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Computational analysis of protein synthesis, diffusion, and binding in compartmental biochips
Published in Microbial cell factories (30-11-2023)“…Protein complex assembly facilitates the combination of individual protein subunits into functional entities, and thus plays a crucial role in biology and…”
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Programming multi-protein assembly by gene-brush patterns and two-dimensional compartment geometry
Published in Nature nanotechnology (01-09-2020)“…The assembly of protein machines in cells is precise, rapid, and coupled to protein synthesis with regulation in space and time. The assembly of natural and…”
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On the Capturing of Low-Energy Electrons by DNA
Published in Proceedings of the National Academy of Sciences - PNAS (04-01-2005)“…Many of the mutagenic or lethal effects of ionization radiation can be attributed to damage caused to the DNA by low-energy electrons. To gain insight on the…”
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Chirality-induced spin-selective properties of self-assembled monolayers of DNA on gold
Published in Physical review letters (27-01-2006)“…Here we show that self-assembled monolayers on gold of double-stranded DNA oligomers interact with polarized electrons similarly to a strong and oriented…”
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Controlling the Adsorption and Reactivity of DNA on Gold
Published in Langmuir (09-12-2003)“…Due to its coding nature, the many chemical and enzymatic manipulations that it can undergo, and its relative stability, DNA is being used as a scaffold and a…”
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Electric-Field Manipulation of a Compartmentalized Cell-Free Gene Expression Reaction
Published in ACS synthetic biology (17-08-2018)“…Direct electric-field manipulation of gene expression reactions would simplify the design of biochemical networks by replacing complex biomolecular…”
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Autonomous synthesis and assembly of a ribosomal subunit on a chip
Published in Science advances (01-04-2020)“…Synthesis of ribosomal RNA and proteins from surface-tethered genes allows dynamic reconstruction of ribosome subunit biogenesis. Ribosome biogenesis is an…”
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10
Boundary-Free Ribosome Compartmentalization by Gene Expression on a Surface
Published in ACS synthetic biology (19-03-2021)“…The design of artificial cell models based on minimal surface-bound transcription–translation reactions aims to mimic the compartmentalization facilitated by…”
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Compartmentalization by directional gene expression
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2010)“…The coalescence of basic biochemical reactions into compartments is a major hallmark of a living cell. Using surface-bound DNA and a transcription reaction, we…”
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Sequence Dependence of Charge Transport Properties of DNA
Published in The journal of physical chemistry. B (11-05-2006)“…The electrical conduction through three short oligomers (26 base pairs, 8 nm long) with differing numbers of GC base pairs was measured. One strand is…”
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Cell-Free Co-synthesis of Protein Nanoassemblies: Tubes, Rings, and Doughnuts
Published in Nano letters (01-03-2007)“…We used a cell-free transcription/translation system to synthesize structural proteins of the T4 bacteriophage. We focused on two proteins that participate in…”
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14
Synthetic gene brushes: a structure-function relationship
Published in Molecular systems biology (2008)“…We present the assembly of gene brushes by means of a photolithographic approach that allows us to control the density of end‐immobilized linear…”
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Controlling the Reactivity of Adsorbed DNA on Template Surfaces
Published in Langmuir (05-02-2008)“…The ability to place DNA on surfaces with increased and controllable reactivity is of fundamental importance in the development of next-generation DNA and…”
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Three-Dimensional Surface Patterning by DNA-Modifying Enzymes
Published in ACS applied materials & interfaces (28-10-2009)“…Self-assembled patterned multilayers may be fabricated using DNA monolayers and the orchestrated reactions of DNA-modifying enzymes. To demonstrate this…”
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Toward Memory in a DNA Brush: Site-Specific Recombination Responsive to Polymer Density, Orientation, and Conformation
Published in Journal of the American Chemical Society (03-05-2023)“…Site-specific recombination is a cellular process for the integration, inversion, and excision of DNA segments that could be tailored for memory transactions…”
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18
Gene Expression on DNA Biochips Patterned with Strand‐Displacement Lithography
Published in Angewandte Chemie International Edition (16-04-2018)“…Lithographic patterning of DNA molecules enables spatial organization of cell‐free genetic circuits under well‐controlled experimental conditions. Here, we…”
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Cell-Free Gene Expression from DNA Brushes
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Linear double-stranded DNA polymers coding for synthetic genes immobilized on a surface form a brush as a center for cell-free gene expression, with DNA…”
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Emergent Properties of Dense DNA Phases toward Artificial Biosystems on a Surface
Published in Accounts of chemical research (17-06-2014)“…Conspectus The expression of genes in a cell in response to external signals or internal programs occurs within an environment that is compartmentalized and…”
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