Search Results - "Datwyler, Saul A."

Evaluation of Acute Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 Plasma Levels in Traumatic Brain Injury Patients with and without Intracranial Lesions by Biberthaler, Peter, Musaelyan, Ksenia, Krieg, Sandro, Meyer, Bernhard, Stimmer, Herbert, Zapf, Julian, von Matthey, Francesca, Chandran, Raj, Marino, Jaime A, Beligere, Gangamani, Hoffmann, Markus, Zhang, Hongwei, Datwyler, Saul A, McQuiston, Beth

“…This pilot study aimed to evaluate the association of plasma ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial fibrillary acidic protein (GFAP), and S100…”
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Heparin Strongly Induces Soluble Fms-Like Tyrosine Kinase 1 Release In Vivo and In Vitro—Brief Report by Searle, Julia, Mockel, Martin, Gwosc, Stefanie, Datwyler, Saul A, Qadri, Fatimunnisa, Albert, Gesa I, Holert, Fabian, Isbruch, Annette, Klug, Lars, Muller, Dominik N, Dechend, Ralf, Muller, Reinhold, Vollert, Joern O, Slagman, Anna, Mueller, Christian, Herse, Florian

“…OBJECTIVE—Soluble fms-like tyrosine kinase 1 (sFlt1) is involved in the pathophysiology of preeclampsia and coronary artery disease. Because sFlt1 has a…”
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Effect of Collection Tube Type and Preanalytical Handling on Myeloperoxidase Concentrations by Shih, Jessie, Datwyler, Saul A, Hsu, Stephen C, Matias, Matthew S, Pacenti, David P, Lueders, Christian, Mueller, Christian, Danne, Oliver, Mockel, Martin

“…Myeloperoxidase (MPO) has shown potential as a marker for cardiovascular disease. Limited studies have been published with a variety of sample types, resulting…”
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Haptoglobin phenotype, angiogenic factors, and preeclampsia risk by Weissgerber, Tracey L., PhD, Roberts, James M., MD, Jeyabalan, Arun, MD, Powers, Robert W., PhD, Lee, MinJae, PhD, Datwyler, Saul A., PhD, Gandley, Robin E., PhD

“…Objective We sought to determine whether haptoglobin (Hp) phenotype is related to preeclampsia risk, or to plasma concentrations of soluble endoglin (sEng),…”
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Accuracy of a rapid glial fibrillary acidic protein/ubiquitin carboxyl‐terminal hydrolase L1 test for the prediction of intracranial injuries on head computed tomography after mild traumatic brain injury by Bazarian, Jeffrey J., Welch, Robert D., Caudle, Krista, Jeffrey, Craig A., Chen, James Y., Chandran, Raj, McCaw, Tamara, Datwyler, Saul A., Zhang, Hongwei, McQuiston, Beth

“…Objective The objective was to determine the accuracy of a new, rapid blood test combining measurements of both glial fibrillary acidic protein (GFAP) and…”
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Low Placental Growth Factor Across Pregnancy Identifies a Subset of Women With Preterm Preeclampsia: Type 1 Versus Type 2 Preeclampsia? by Powers, Robert W, Roberts, James M, Plymire, Daniel A, Pucci, Dominick, Datwyler, Saul A, Laird, Don M, Sogin, David C, Jeyabalan, Arun, Hubel, Carl A, Gandley, Robin E

“…Preeclampsia is a heterogeneous syndrome affecting 3% to 5% of all pregnancies. An imbalance of the antiangiogenic and proangiogenic factors, soluble receptor…”
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Restructuring of an RNA Polymerase Holoenzyme Elongation Complex by Lambdoid Phage Q Proteins by Marr, Michael T., Datwyler, Saul A., Meares, Claude F., Roberts, Jeffrey W.

“…The structure of an intermediate in the initiation to elongation transition of Escherichia coli RNA polymerase has been visualized through region-specific DNA…”
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Comparison of GFAP and UCH-L1 Measurements from Two Prototype Assays: The Abbott i-STAT and ARCHITECT Assays by Korley, Frederick K, Datwyler, Saul A, Jain, Sonia, Sun, Xiaoying, Beligere, Gangamani, Chandran, Raj, Marino, Jaime A, McQuiston, Beth, Zhang, Hongwei, Caudle, Krista L, Wang, Kevin K W, Puccio, Ava M, Okonkwo, David O, Yue, John K, Taylor, Sabrina R, Markowitz, Amy, Manley, Geoffrey T, Diaz-Arrastia, Ramon

“…Glial fibrillary acidic protein (GFAP) and ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) may aid in the evaluation of traumatic brain injury (TBI). The…”
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High Viral Load and Elevated Angiogenic Markers Associated With Increased Risk of Preeclampsia Among Women Initiating Highly Active Antiretroviral Therapy in Pregnancy in the Mma Bana Study, Botswana by POWIS, Kathleen M, MCELRATH, Thomas F, MACHAKAIRE, Esther, LOCKMAN, Shahin, ESSEX, Max, SHAPIRO, Roger L, HUGHES, Michael D, OGWU, Anthony, SOUDA, Sajini, DATWYLER, Saul A, VON WIDENFELT, Erik, MOYO, Sikhulile, NADAS, Marisa, MAKHEMA, Joseph

“…Risk factors associated with preeclampsia in HIV-infected women remain largely unknown. Systemic angiogenic imbalance contributes to preeclampsia in…”
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Potential interference by antineutrophil cytoplasmic autoantibodies in myeloperoxidase immunoassays by Datwyler, Saul A, Hsu, Stephen C, Matias, Matthew S, Pacenti, David P, Shih, Jessie

“…Antineutrophil cytoplasmic autoantibodies (ANCAs) are known to exist in patients with diseases characterized by primary systematic vasculitis, such as Wegener…”
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Principles and methods of affinity cleavage in studying transcription by Meares, Claude F, Datwyler, Saul A, Schmidt, Brian D, Owens, Jeffrey, Ishihama, Akira

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Targeted Protein Footprinting:  Where Different Transcription Factors Bind to RNA Polymerase by Traviglia, Stacey L, Datwyler, Saul A, Yan, Dalai, Ishihama, Akira, Meares, Claude F

“…Gene transcription is regulated through the interactions of RNA polymerase (RNAP) with transcription factors, such as the bacterial σ proteins. We have devised…”
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An efficient preparation of polyanionic affinity agent and its evaluation for the measurement of glycated hemoglobin by Reddy, Rajarathnam E., Pan, You, Johnson, Donald D., Chen, Yon-Yih, Datwyler, Saul A., Hauptman, Michelle S., Thottathil, John K.

“…An efficient method was developed for the preparation of polyanionic affinity agent ( 3) and its application in the measurement of glycated hemoglobin was…”
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Mapping Protein−Protein Interactions with a Library of Tethered Cutting Reagents:  The Binding Site of σ70 on Escherichia coli RNA Polymerase by Traviglia, Stacey L, Datwyler, Saul A, Meares, Claude F

“…Surface-exposed lysine amino groups and other reactive nucleophiles of the σ70 protein were conjugated with the cutting reagent iron…”
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LOW PGF ACROSS PREGNANCY IDENTIFIES A SUBSET OF WOMEN WITH PRETERM PREECLAMPSIA; TYPE 1 vs. TYPE 2 PREECLAMPSIA? by Powers, Robert W., Roberts, James M., Plymire, Daniel A., Pucci, Dominick, Datwyler, Saul A., Laird, Don M., Sogin, David C., Jeyabalan, Arun, Hubel, Carl A., Gandley, Robin E.

“…Preeclampsia is a heterogeneous syndrome affecting 3–5% of all pregnancies. An imbalance of the anti and pro-angiogenic factors, soluble receptor fms-like…”
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Protein–protein interactions mapped by artificial proteases: where σ factors bind to RNA polymerase by Datwyler, Saul A., Meares, Claude F.

“…Interactions between proteins are important to understand but difficult to study. Conjugating a protein to a small artificial protease endows it with the…”
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Mapping protein-protein interactions with a library of tethered cutting reagents: the binding site of sigma 70 on Escherichia coli RNA polymerase by Traviglia, S L, Datwyler, S A, Meares, C F

“…Surface-exposed lysine amino groups and other reactive nucleophiles of the sigma 70 protein were conjugated with the cutting reagent iron…”
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