Search Results - "Datta, Sayantan"

The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD by Datta, Sayantan, Cano, Marisol, Ebrahimi, Katayoon, Wang, Lei, Handa, James T.

“…The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that interacts with photoreceptors on its apical side and with Bruch's…”
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Illuminating a new path to multicellularity by Datta, Sayantan, Ratcliff, William C

“…A new species of multicellular bacteria broadens our understanding of prokaryotic multicellularity and provides insight into how multicellular organisms arise…”
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The impact of lipids, lipid oxidation, and inflammation on AMD, and the potential role of miRNAs on lipid metabolism in the RPE by Jun, Sujung, Datta, Sayantan, Wang, Lei, Pegany, Roma, Cano, Marisol, Handa, James T.

“…The accumulation of lipids within drusen, the epidemiologic link of a high fat diet, and the identification of polymorphisms in genes involved in lipid…”
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Caste Concerns in Transgender Communities in India: Contesting Cohesiveness, Broadening Horizon(s) by Kumar, Pushpesh, Datta, Sayantan

“…In this article, we recount the development of an anti-caste consciousness in queer and transgender rights movements in India. We begin by tracing the history…”
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DYRK1A interacts with the tuberous sclerosis complex and promotes mTORC1 activity by Wang, Pinhua, Sarkar, Sunayana, Zhang, Menghuan, Xiao, Tingting, Kong, Fenhua, Zhang, Zhe, Balasubramanian, Deepa, Jayaram, Nandan, Datta, Sayantan, He, Ruyu, Wu, Ping, Chao, Peng, Zhang, Ying, Washburn, Michael, Florens, Laurence A, Nagarkar-Jaiswal, Sonal, Jaiswal, Manish, Mohan, Man

“…DYRK1A, a ubiquitously expressed kinase is linked to the dominant intellectual developmental disorder, microcephaly, and Down syndrome in humans. It regulates…”
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Constitutive expression of the Type VI Secretion System carries no measurable fitness cost in Vibrio cholerae by Zhang, Christopher, Datta, Sayantan, Ratcliff, William C., Hammer, Brian K.

“…The Type VI Secretion System (T6SS) is a widespread and highly effective mechanism of microbial warfare; it confers the ability to efficiently kill susceptible…”
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A sustainable bi-objective inventory model with source-based emissions and plan-based green investments under inflation and the present value of money by Tapan Kumar Datta, Datta, Sayantan, Goswami, Adrijit

“…The paper develops a finite-horizon inventory model with source-based emissions, plan-based green investments under inflation, and the present value of money…”
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Comprehensive SNP scan of DNA repair and DNA damage response genes reveal multiple susceptibility loci conferring risk to tobacco associated leukoplakia and oral cancer by Mondal, Pinaki, Datta, Sayantan, Maiti, Guru Prasad, Baral, Aradhita, Jha, Ganga Nath, Panda, Chinmay Kumar, Chowdhury, Shantanu, Ghosh, Saurabh, Roy, Bidyut, Roychoudhury, Susanta

“…Polymorphic variants of DNA repair and damage response genes play major role in carcinogenesis. These variants are suspected as predisposition factors to Oral…”
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‘It’s nice that we can do that too’: investigating transgender persons' negotiations with identity and community questions in Indian science institutions by Datta, Sayantan

“…Abstract In 2014, the Indian Supreme Court passed the landmark NALSA v. Union of India judgment that not only granted transgender persons the right to…”
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Mitochondrial calcium at the synapse by Datta, Sayantan, Jaiswal, Manish

“…Mitochondria are dynamic organelles, which serve various purposes, including but not limited to the production of ATP and various metabolites, buffering ions,…”
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Epistemological Deviant, Epistemic Abjection and Lost Opportunities: A Case Study of a Muslim Trans Intersex Student’s Othering and Dehumanisation in an Indian Science Classroom by Datta, Sayantan

“…This article sheds light on the registers of violence through which people from marginalised groups—especially non-normative or minoritised collectivities of…”
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Pink1‐mitophagy and Nrf2‐stress response mediated novel mitochondrial retrograde signaling affects RPE structure and function by Datta, Sayantan, Handa, James

“…Abstract only Purpose Dry age related macular degeneration (AMD) is the leading cause of blindness in the elderly with no effective treatment. Dysfunction and…”
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Queer and trans community building in post-NALSA and post-377 India: a critical reflection by Kumar, Pushpesh, Datta, Sayantan, Mishra, Neha

“…Abstract This article reflects on contestations that mark queer and trans community building in post- National Legal Services Authority (NALSA) and post-377…”
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Prioritized Indoor Exploration with a Dynamic Deadline by Datta, Sayantan, Akella, Srinivas

“…Indoor exploration using mobile robots has typically focused on exploring the entire environment without considering deadlines. This paper introduces a…”
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Lipids, oxidized lipids, oxidation-specific epitopes, and Age-related Macular Degeneration by Handa, James T., Cano, Marisol, Wang, Lei, Datta, Sayantan, Liu, Tongyun

“…Age-related Macular Degeneration (AMD) is the leading cause of blindness among the elderly in western societies. While antioxidant micronutrient treatment is…”
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Prioritized Robotic Exploration with Dynamic Deadlines by Datta, Sayantan

“…Autonomous exploration using mobile robots, commonly referred to as robotic exploration, entails simultaneously performing robot perception, localization, and…”
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Nrf2 deficiency decreases NADPH from impaired IDH shuttle and pentose phosphate pathway in retinal pigmented epithelial cells to magnify oxidative stress‐induced mitochondrial dysfunction by Cano, Marisol, Datta, Sayantan, Wang, Lei, Liu, Tongyun, Flores‐Bellver, Miguel, Sachdeva, Mira, Sinha, Debasish, Handa, James T.

“…The nuclear factor‐erythroid 2‐related factor‐2 (Nrf2), a major antioxidant transcription factor, is decreased in several age‐related diseases including…”
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Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity by Datta, Sayantan, Cano, Marisol, Satyanarayana, Ganesh, Liu, Tongyun, Wang, Lei, Wang, Jie, Cheng, Jie, Itoh, Kie, Sharma, Anjali, Bhutto, Imran, Kannan, Rangaramanujam, Qian, Jiang, Sinha, Debasish, Handa, James T.

“…Age-related macular degeneration (AMD), the leading cause of blindness among the elderly, is without treatment for early disease. Degenerative retinal pigment…”
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Association of DNA sequence variation in mitochondrial DNA polymerase with mitochondrial DNA synthesis and risk of oral cancer by Datta, Sayantan, Ray, Anindita, Roy, Roshni, Roy, Bidyut

“…Enzymes responsible for mitochondrial (mt) DNA synthesis and transcription are encoded by nuclear genome and inherited mutations in these genes may play…”
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Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation by Wang, Lei, Cano, Marisol, Datta, Sayantan, Wei, Hong, Ebrahimi, Katayoon B, Gorashi, Yara, Garlanda, Cecilia, Handa, James T

“…The discovery that genetic abnormalities in complement factor H (FH) are associated with an increased risk for age‐related macular degeneration (AMD), the most…”
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