Search Results - "Datta, Aditi Ashish"

Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis by Babuta, Mrigya, Morel, Caroline, de Carvalho Ribeiro, Marcelle, Calenda, Charles, Ortega-Ribera, Martí, Thevkar Nagesh, Prashanth, Copeland, Christopher, Zhuang, Yuan, Wang, Yanbo, Cho, Yeonhee, Joshi, Radhika, Brezani, Viliam, Hawryluk, Danielle, Datta, Aditi Ashish, Mehta, Jeeval, Nasser, Imad, Szabo, Gyongyi

“…Alcohol use in metabolic dysfunction-associated steatohepatitis (MASH) is associated with an increased risk of fibrosis and liver-related death. Here, we aimed…”
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Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1β Axis in the Liver by Babuta, Mrigya, Nagesh, Prashanth Thevkar, Datta, Aditi Ashish, Remotti, Victoria, Zhuang, Yuan, Mehta, Jeeval, Lami, Francesca, Wang, Yanbo, Szabo, Gyongyi

“…Binge drinking in obese patients positively correlates with accelerated liver damage and liver-related death. However, the underlying mechanism and the effect…”
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In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis by Nagesh, Prashanth Thevkar, Cho, Yeonhee, Zhuang, Yuan, Babuta, Mrigya, Ortega-Ribera, Marti, Joshi, Radhika, Brezani, Veronika, Patel, Arman, Datta, Aditi Ashish, Brezani, Viliam, Hsieh, Yun-Cheng, Ramos, Adriana, Mehta, Jeeval, Copeland, Christopher, Kanata, Eleni, Jiang, Zhenghui Gordon, Vlachos, Ioannis, Asara, John, Szabo, Gyongyi

“…Severe alcohol-associated hepatitis (AH) is a life-threatening form of alcohol-associated liver disease. Liver neutrophil infiltration is a hallmark of AH, yet…”
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A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis by Babuta, Mrigya, Morel, Caroline, de Carvalho Ribeiro, Marcelle, Datta, Aditi Ashish, Calenda, Charles, Copeland, Christopher, Nasser, Imad, Szabo, Gyongyi

“…The recent increase in the incidence of alcohol-associated hepatitis (AH) coincides with the obesity epidemic in the United States. However, current mouse…”
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