Search Results - "Datsomor, Alex"
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CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes
Published in Scientific reports (17-05-2019)“…Atlantic salmon can synthesize polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (20:5n-3), arachidonic acid (20:4n-6) and docosahexaenoic…”
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CRISPR/Cas9-mediated editing of Δ5 and Δ6 desaturases impairs Δ8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.)
Published in Scientific reports (15-11-2019)“…The in vivo functions of Atlantic salmon fatty acyl desaturases ( fads2 ), Δ6fads2-a , Δ6fads2-b , Δ6fads2-c and Δ5fads2 in long chain polyunsaturated fatty…”
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Efficient transfection of Atlantic salmon primary hepatocyte cells for functional assays and gene editing
Published in G3 : genes - genomes - genetics (11-04-2023)“…Abstract The expansion of genomic resources for Atlantic salmon over the past half decade has enabled efficient interrogation of genetic traits by large-scale…”
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Molecular Regulation of Biosynthesis of Long Chain Polyunsaturated Fatty Acids in Atlantic Salmon
Published in Marine biotechnology (New York, N.Y.) (01-08-2022)“…Salmon is a rich source of health-promoting omega-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA), such as eicosapentaenoic acid (EPA, 20:5n-3) and…”
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Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)
Published in BMC genomics (19-11-2020)“…With declining wild fish populations, farmed salmon has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA). However,…”
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Functional validation of transposable element–derived cis-regulatory elements in Atlantic salmon
Published in G3 : genes - genomes - genetics (11-04-2023)“…Abstract Transposable elements (TEs) are hypothesized to play important roles in shaping genome evolution following whole-genome duplications (WGDs), including…”
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Rapid high throughput SYBR green assay for identifying the malaria vectors Anopheles arabiensis, Anopheles coluzzii and Anopheles gambiae s.s. Giles
Published in PloS one (19-04-2019)“…The Anopheles gambiae sensu lato species complex consists of a number of cryptic species with different habitats and behaviours. These morphologically…”
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Insecticide susceptibility of natural populations of Anopheles coluzzii and Anopheles gambiae (sensu stricto) from Okyereko irrigation site, Ghana, West Africa
Published in Parasites & vectors (31-03-2016)“…The increasing spread of insecticide resistance in malaria vectors has been well documented across sub-Saharan Africa countries. The influence of irrigation on…”
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