Search Results - "Datler, Hannes"

Cell Type-Specific Roles of NF-κB Linking Inflammation and Thrombosis by Mussbacher, Marion, Salzmann, Manuel, Brostjan, Christine, Hoesel, Bastian, Schoergenhofer, Christian, Datler, Hannes, Hohensinner, Philipp, Basílio, José, Petzelbauer, Peter, Assinger, Alice, Schmid, Johannes A

“…The transcription factor NF-κB is a central mediator of inflammation with multiple links to thrombotic processes. In this review, we focus on the role of NF-κB…”
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PI3K Signaling in Dendritic Cells Aggravates DSS-Induced Colitis by Kuttke, Mario, Hromadová, Dominika, Yildirim, Ceren, Brunner, Julia S, Vogel, Andrea, Paar, Hannah, Peters, Sophie, Weber, Maria, Hofmann, Melanie, Kerndl, Martina, Kieler, Markus, Datler, Hannes, Musiejovsky, Laszlo, Salzmann, Manuel, Lang, Michaela, Soukup, Klara, Halfmann, Angela, Sharif, Omar, Schabbauer, Gernot

“…Aberrant innate immune responses to the gut microbiota are causally involved in the pathogenesis of inflammatory bowel diseases (IBD). The exact triggers and…”
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JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction by Vogel, Andrea, Martin, Katharina, Soukup, Klara, Halfmann, Angela, Kerndl, Martina, Brunner, Julia S., Hofmann, Melanie, Oberbichler, Laura, Korosec, Ana, Kuttke, Mario, Datler, Hannes, Kieler, Markus, Musiejovsky, Laszlo, Dohnal, Alexander, Sharif, Omar, Schabbauer, Gernot

“…Dendritic cells (DCs) induce peripheral T cell tolerance, but cell-intrinsic signaling cascades governing their stable tolerogenesis remain poorly defined…”
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PI3K activity in dendritic cells exerts paradoxical effects during autoimmune inflammation by Datler, Hannes, Vogel, Andrea, Kerndl, Martina, Baumgartinger, Christina, Musiejovsky, Laszlo, Makivic, Nina, Frech, Sophie, Niederreiter, Birgit, Haider, Thomas, Pühringer, Marlene, Brunner, Julia Stefanie, Sharif, Omar, Schabbauer, Gernot

“…•Dendritic cell (DC) expressed PI3K restrains cytokine secretion and antigen presentation.•DC expressed PI3K dampens EAE associated TH1 and TH17…”
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Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia by Schrottmaier, Waltraud Cornelia, Kral-Pointner, Julia Barbara, Salzmann, Manuel, Mussbacher, Marion, Schmuckenschlager, Anna, Pirabe, Anita, Brunnthaler, Laura, Kuttke, Mario, Maier, Barbara, Heber, Stefan, Datler, Hannes, Ekici, Yasemin, Niederreiter, Birgit, Heber, Ulrike, Blomgren, Bo, Gorki, Anna-Dorothea, Söderberg-Nauclér, Cecilia, Payrastre, Bernard, Gratacap, Marie-Pierre, Knapp, Sylvia, Schabbauer, Gernot, Assinger, Alice

“…Phosphatidylinositol 3-kinase catalytic subunit p110β is involved in tumorigenesis and hemostasis. However, it remains unclear if p110β also regulates…”
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Myeloid but not epithelial tissue factor exerts protective anti-inflammatory properties in acid aspiration-induced acute lung injury by Schabbauer, Gernot, Kral-Pointner, Julia, Schrottmaier, Waltraud, Horvath, Vera, Datler, Hannes, Hell, Lena, Ay, Cihan, Niederreiter, Birgit, Jilma, Bernd, Schmid, Johannes, Assinger, Alice, Mackman, Nigel, Knapp, Sylvia

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Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis by Sahin, Emine, Brunner, Julia S, Kral, Julia B, Kuttke, Mario, Hanzl, Leslie, Datler, Hannes, Paar, Hannah, Neuwinger, Nick, Saferding, Victoria, Zinser, Elisabeth, Halfmann, Angela, Soukup, Klara, Hainzl, Eva, Lohmeyer, Tobias, Niederreiter, Birgit, Haider, Thomas, Dohnal, Alexander M, Krönke, Gerhard, Blüml, Stephan, Schabbauer, Gernot

“…The PI3K signaling cascade in APCs has been recognized as an essential pathway to initiate, maintain, and resolve immune responses. In this study, we…”
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