Search Results - "Datki, Zsolt L."

Proteomic study of the toxic effect of oligomeric Aβ1‐42 in situ prepared from ‘iso‐Aβ1‐42’ by Földi, István, Datki, Zsolt L., Szabó, Zoltán, Bozsó, Zsolt, Penke, Botond, Janáky, Tamás

“…J. Neurochem. (2011) 117, 691–702. Alzheimer’s disease (AD) is the most prevalent form of neurodegenerative disorders even so the exact pathomechanism is still…”
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A novel application of the fluorescent dye bis-ANS for labeling neurons in acute brain slices by Mozes, Emese, Hunya, Akos, Toth, Aniko, Ayaydin, Ferhan, Penke, Botond, Datki, Zsolt L

“…Highlights ► Cell-impermeant oligomer specific fluorescent dye, bis-ANS. ► Labeling mechanically damaged but still viable neurons in acute brain slices. ► Both…”
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Extracellular Zn2+ Is Essential for Amyloid β1-42-Induced Cognitive Decline in the Normal Brain and Its Rescue by Takeda, Atsushi, Tamano, Haruna, Tempaku, Munekazu, Sasaki, Miku, Uematsu, Chihiro, Sato, Shoko, Kanazawa, Hiroaki, Datki, Zsolt L, Adlard, Paul A, Bush, Ashley I

“…Brain Aβ1-42 accumulation is considered an upstream event in pathogenesis of Alzheimer's disease. However, accumulating evidence indicates that other…”
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Extracellular Zn 2+ Is Essential for Amyloid β 1-42 -Induced Cognitive Decline in the Normal Brain and Its Rescue by Takeda, Atsushi, Tamano, Haruna, Tempaku, Munekazu, Sasaki, Miku, Uematsu, Chihiro, Sato, Shoko, Kanazawa, Hiroaki, Datki, Zsolt L, Adlard, Paul A, Bush, Ashley I

“…Brain Aβ accumulation is considered an upstream event in pathogenesis of Alzheimer's disease. However, accumulating evidence indicates that other neurochemical…”
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Biological Activities of Four Adaptogenic Plant Extracts and Their Active Substances on a Rotifer Model by Horváth, Attila, Csupor, Dezső, Datki, Zsolt L., Mácsai, Lilla, Zomborszki, Zoltán P.

“…Rotifers have been widely used as well-characterized models of aging, since their multiorgan character makes them suitable as in vivo toxicological and…”
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Adiponectin Receptors Are Less Sensitive to Stress in a Transgenic Mouse Model of Alzheimer's Disease by Várhelyi, Zoltán P, Kálmán, János, Oláh, Zita, Ivitz, Eszter V, Fodor, Eszter K, Sántha, Miklós, Datki, Zsolt L, Pákáski, Magdolna

“…Adiponectin and leptin are implicated in the initiation and pathomechanism of Alzheimer's disease (AD). The serum concentrations of these adipokines has been…”
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Proteomic study of the toxic effect of oligomeric A beta 1-42 in situ prepared from 'iso-A beta 1-42' by Foldi, Istvan, Datki, Zsolt L, Szabo, Zoltan, Bozso, Zsolt, Penke, Botond, Janaky, Tamas

“…Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disorders even so the exact pathomechanism is still unclear. Recently, it is widely…”
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Proteome-wide study of endoplasmic reticulum stress induced by thapsigargin in N2a neuroblastoma cells by Földi, István, Tóth, Anikó M., Szabó, Zoltán, Mózes, Emese, Berkecz, Róbert, Datki, Zsolt L., Penke, Botond, Janáky, Tamás

“…► Strong crosstalk between mitochondria and endoplasmic reticulum. ► Upregulated mitochondrial enzymes during endoplasmic reticulum stress. ► Potentially…”
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Reversible mechanical unzipping of amyloid beta-fibrils by Kellermayer, Miklós S Z, Grama, László, Karsai, Arpád, Nagy, Attila, Kahn, Amram, Datki, Zsolt L, Penke, Botond

“…Amyloid fibrils are self-associating filamentous structures, the deposition of which is considered to be one of the most important factors in the pathogenesis…”
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A novel and simple fluorescence method for the measurement of presynaptic vesicular zinc release in acute hippocampal slices with a fluorescence plate reader by Datki, Zsolt L, Hunya, Ákos, Penke, Botond

“…Abstract The synaptic vesicles in the hippocampal neuronal terminals are abundantly supplied with zinc ions (Zn2+ ), which can be released into the synaptic…”
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Differences between normal and alpha-synuclein overexpressing SH-SY5Y neuroblastoma cells after Aβ(1-42) and NAC treatment by Hunya, Ákos, Földi, István, Szegedi, Viktor, Soós, Katalin, Zarándi, Márta, Szabó, Antal, Zádori, Dénes, Penke, Botond, Datki, Zsolt L

“…Abstract Alpha-synuclein (αSN) plays a major role in numerous neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. Intracellular…”
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Extracellular Zn^sup 2+^ Is Essential for Amyloid β^sub 1–42^-Induced Cognitive Decline in the Normal Brain and Its Rescue by Takeda, Atsushi, Tamano, Haruna, Tempaku, Munekazu, Sasaki, Miku, Uematsu, Chihiro, Sato, Shoko, Kanazawa, Hiroaki, Datki, Zsolt L, Adlard, Paul A, Bush, Ashley I

“…Brain Aβ1–42 accumulation is considered an upstream event in pathogenesis of Alzheimer's disease. However, accumulating evidence indicates that other…”
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Proteomic study of the toxic effect of oligomeric A[beta]1-42 in situ prepared from 'iso-A[beta]1-42' by Földi, István, Datki, Zsolt L, Szabó, Zoltán, Bozsó, Zsolt, Penke, Botond, Janáky, Tamás

“…J. Neurochem. (2011) 117, 691-702. Abstract Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disorders even so the exact pathomechanism…”
Get full text

Proteomic study of the toxic effect of oligomeric Aβ1-42 in situ prepared from ‘iso-Aβ1-42’: Toxic effect of oligomeric Aβ1-42 by Földi, István, Datki, Zsolt L., Szabó, Zoltán, Bozsó, Zsolt, Penke, Botond, Janáky, Tamás

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Differences between normal and alpha-synuclein overexpressing SH-SY5Y neuroblastoma cells after Abeta(1-42) and NAC treatment by Hunya, Akos, Földi, István, Szegedi, Viktor, Soós, Katalin, Zarándi, Márta, Szabó, Antal, Zádori, Dénes, Penke, Botond, Datki, Zsolt L

“…Alpha-synuclein (alphaSN) plays a major role in numerous neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. Intracellular…”
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Reversible Mechanical Unzipping of Amyloid β-Fibrils by Miklós S. Z. Kellermayer, László Grama, Árpád Karsai, Attila Nagy, Amram Kahn, Zsolt L. Datki, Botond Penke

“…Amyloid fibrils are self-associating filamentous structures, the deposition of which is considered to be one of the most important factors in the pathogenesis…”
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In Vitro Modelling of Neurodegeneration and Neuroprotection Specific for Alzheimer's Disease in Cell Cultures by Datki, Zsolt L

“…Many neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease, amyotrophic lateral sclerosis, prion- and Huntington's disease are…”
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