Search Results - "Datiane de Morais Oliveira – Tintino, Cícera"
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Comparative Antibacterial and Efflux Pump Inhibitory Activity of Isolated Nerolidol, Farnesol, and α-Bisabolol Sesquiterpenes and Their Liposomal Nanoformulations
Published in Molecules (Basel, Switzerland) (01-11-2023)“…The efflux systems are considered important mechanisms of bacterial resistance due to their ability to extrude various antibiotics. Several naturally occurring…”
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Liposome evaluation in inhibiting pump efflux of NorA of Staphylococcus aureus
Published in Chemistry and physics of lipids (01-07-2022)“…Liposomes, in addition to providing greater efficacy to antibiotics, decrease toxicity and increase selectivity. This work has as main objectives the…”
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Meldrum's acid derivates are MepA efflux pump inhibitors: In vitro and in silico essays
Published in Journal of basic microbiology (01-02-2024)“…Efflux pumps are proteins capable of expelling antibiotics from bacterial cells, have emerged as a major mechanism of bacterial resistance. In the ongoing…”
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Evaluation of the inhibitory effect of isopulegol (ISO) and its β-cyclodextrin inclusion complex (ISO/β-CD) on the reversal of Staphylococcus aureus efflux pump activity
Published in Polymer bulletin (Berlin, Germany) (2024)“…Staphylococcus aureus is known to be a human pathogen and is often resistant to antibiotics, so there is a demand for new treatment alternatives that have the…”
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Valencene, Nootkatone and Their Liposomal Nanoformulations as Potential Inhibitors of NorA, Tet(K), MsrA, and MepA Efflux Pumps in Staphylococcus aureus Strains
Published in Pharmaceutics (01-10-2023)“…Valencene and nootkatone are aromatic sesquiterpenes with known biological activities, such as antimicrobial, antioxidant, anti-inflammatory, and antitumor…”
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Modification of Antibiotic Activity by Fixed Oil of the Artocarpus heterophyllus Almond against Standard and Multidrug-Resistant Bacteria Strains
Published in Biology (Basel, Switzerland) (16-12-2022)“…(jackfruit) is an evergreen tree distributed in tropical regions and is among the most studied species of the genus . The jackfruit almond has been highlighted…”
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Antibacterial Activity of the Essential Oil of Piper tuberculatum Jacq. Fruits against Multidrug-Resistant Strains: Inhibition of Efflux Pumps and β-Lactamase
Published in Plants (Basel) (19-06-2023)“…Antimicrobial resistance has become a growing public health concern in recent decades, demanding a search for new effective treatments. Therefore, this study…”
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Biological activities of the essential oil from the leaves of Lantana montevidensis (Spreng) Briq. in mice
Published in Environment, development and sustainability (01-10-2021)“…This work aimed to analyze the chemical composition and evaluate the anti-inflammatory and antinociceptive properties of the essential oil obtained from the…”
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In Vitro and In Silico Biological Evaluation of the Essential Oil from Syzigium cumini Leaves as a Source of Novel Antifungal and Trichomonacidal Agents
Published in Future pharmacology (01-05-2024)“…As microbes develop resistance to various drugs, the treatment of infections becomes increasingly challenging, leading to prolonged illness, heightened…”
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The 1,8-naphthyridines sulfonamides are NorA efflux pump inhibitors
Published in Journal of global antimicrobial resistance. (01-03-2021)“…•1,8-naphthyridine sulfonamides showed synergy with norfloxacin and ethidium bromide.•MICs of multidrug-resistant S. aureus strains SA-1199 and SA-1199B were…”
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Enhancing the Antifungal Efficacy of Fluconazole with a Diterpene: Abietic Acid as a Promising Adjuvant to Combat Antifungal Resistance in Candida spp
Published in Antibiotics (Basel) (01-11-2023)“…The increasing antifungal resistance rates against conventional drugs reveal the urgent need to search for new therapeutic alternatives. In this context,…”
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Impacts of the Residual Trace Metals of Aquaculture in Net Cages on the Quality of Sediment
Published in Life (Basel, Switzerland) (27-01-2023)“…Anthropogenic pollution by trace metals in aquatic environments in semiarid zones is a critical area of investigation. The objective of this study was to…”
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Cytotoxicity and Biological Activities of Geopopolis Extract from the Stingless bee (Melipona scutellaris) in Isolates of Staphylococcus aureus
Published in Chemistry & biodiversity (01-06-2024)“…Geopropolis resins are produced by stingless bees (Meliponinae), developed from the collection of resinous materials, waxes and exudates, from the flora of the…”
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Comparative Analysis of the Antibacterial Activity and HPLC Phytochemical Screening of the Brazilian Red Propolis and the Resin of Dalbergia ecastaphyllum
Published in Chemistry & biodiversity (01-09-2019)“…The aim of this study was to investigate the antibacterial activity of red propolis and resin and their association with standard antibiotics to evaluate…”
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In vitro and in silico inhibitory effects of synthetic and natural eugenol derivatives against the NorA efflux pump in Staphylococcus aureus
Published in Food chemistry (01-02-2021)“…•Compounds with the most functional groups obtained clinically relevant results.•Against SA 1199B only isoeugenol had direct antibacterial activity.•For the…”
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Crotamine derived from Crotalus durissus terrificus venom combined with drugs increases in vitro antibacterial and antifungal activities
Published in Archives of microbiology (01-09-2024)“…This study investigated crotamine (CTA), a peptide derived from the venom of the South American rattlesnake Crotalus durissus terrificus , known for its…”
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In vitro and in silico effect of meldrum's acid-derived compounds on Staphylococcus aureus strains as NorA efflux pump inhibitors
Published in Biophysical chemistry (01-01-2025)“…The misuse of antibiotics has led to an alarming increase in bacterial strains resistant to these drugs. Efflux pumps, which expel antibiotics from bacterial…”
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Liposomal nanoformulations with trans-caryophyllene and caryophyllene oxide: do they have an inhibitory action on the efflux pumps NorA, Tet(K), MsrA, and MepA?
Published in Chemico-biological interactions (25-04-2024)“…This study aimed to evaluate the antibacterial and inhibitory action of NorA, Tet(K), MsrA and MepA efflux pumps in S. aureus strains using the sesquiterpenes…”
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NorA, Tet(K), MepA, and MsrA Efflux Pumps in Staphylococcus aureus , their Inhibitors and 1,8-Naphthyridine Sulfonamides
Published in Current pharmaceutical design (01-01-2023)“…Antibiotic resistance can be characterized, in biochemical terms, as an antibiotic's inability to reach its bacterial target at a concentration that was…”
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Effect of Carvacrol and Thymol on NorA efflux pump inhibition in multidrug-resistant (MDR) Staphylococcus aureus strains
Published in Journal of bioenergetics and biomembranes (01-08-2021)“…Undue exposure to antimicrobials has led to the acquisition and development of sophisticated bacterial resistance mechanisms, such as efflux pumps, which are…”
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