Search Results - "Dathan, Nina A."

Targeting of PED/PEA-15 Molecular Interaction with Phospholipase D1 Enhances Insulin Sensitivity in Skeletal Muscle Cells by Viparelli, Francesca, Cassese, Angela, Doti, Nunzianna, Paturzo, Flora, Marasco, Daniela, Dathan, Nina A., Monti, Simona M., Basile, Giancarlo, Ungaro, Paola, Sabatella, Marco, Miele, Claudia, Teperino, Raffaele, Consiglio, Eduardo, Pedone, Carlo, Beguinot, Francesco, Formisano, Pietro, Ruvo, Menotti

“…Phosphoprotein enriched in diabetes/phosphoprotein enriched in astrocytes (PED/PEA-15) is overexpressed in several tissues of individuals affected by type 2…”
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Sphingolipid metabolic flow controls phosphoinositide turnover at the trans‐Golgi network by Capasso, Serena, Sticco, Lucia, Rizzo, Riccardo, Pirozzi, Marinella, Russo, Domenico, Dathan, Nina A, Campelo, Felix, van Galen, Josse, Hölttä‐Vuori, Maarit, Turacchio, Gabriele, Hausser, Angelika, Malhotra, Vivek, Riezman, Isabelle, Riezman, Howard, Ikonen, Elina, Luberto, Chiara, Parashuraman, Seetharaman, Luini, Alberto, D'Angelo, Giovanni

“…Sphingolipids are membrane lipids globally required for eukaryotic life. The sphingolipid content varies among endomembranes with pre‐ and post‐Golgi…”
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Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii by Alterio, Vincenzo, Langella, Emma, Viparelli, Francesca, Vullo, Daniela, Ascione, Giuseppina, Dathan, Nina A., Morel, François M.M., Supuran, Claudiu T., De Simone, Giuseppina, Monti, Simona Maria

“…Carbonic anhydrases (CAs) catalyze with high efficiency the reversible hydration of carbon dioxide, an essential reaction for many biological processes, such…”
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Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis by Monti, Simona Maria, De Simone, Giuseppina, Dathan, Nina A., Ludwig, Martha, Vullo, Daniela, Scozzafava, Andrea, Capasso, Clemente, Supuran, Claudiu T.

“…Several β-carbonic anhydrases (CAs, EC 4.2.1.1) are present in all land plants examined thus far. Here we report the first detailed biochemical…”
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Faox enzymes inhibited Maillard reaction development during storage both in protein glucose model system and low lactose UHT milk by Troise, Antonio Dario, Dathan, Nina A, Fiore, Alberto, Roviello, Giovanni, Di Fiore, Anna, Caira, Simonetta, Cuollo, Marina, De Simone, Giuseppina, Fogliano, Vincenzo, Monti, Simona M

“…Fructosamines, also known as Amadori products, are formed by the condensation of glucose with the amino group of amino acids or proteins. These compounds are…”
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Biochemical characterization of the chloroplastic β-carbonic anhydrase from Flaveria bidentis (L.) "Kuntze" by Dathan, Nina A, Alterio, Vincenzo, Troiano, Elisa, Vullo, Daniela, Ludwig, Martha, De Simone, Giuseppina, Supuran, Claudiu T, Monti, Simona M

“…C3 and C4 plant carbonic anhydrases (CAs) are zinc-enzymes that catalyze the reversible hydration of CO2. They are sub-divided in three classes: α, β and γ,…”
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Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis by D'ambrosio, Katia, Lopez, Marie, Dathan, Nina A., Ouahrani-Bettache, Safia, Köhler, Stephan, Ascione, Giuseppina, Monti, Simona Maria, Winum, Jean-Yves, De Simone, Giuseppina

“…l-Histidinol dehydrogenase from Brucella suis (BsHDH) is an enzyme involved in the histidine biosynthesis pathway which is absent in mammals, thus representing…”
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Activation of RET as a Dominant Transforming Gene by Germline Mutations of MEN2A and MEN2B by Santoro, Massimo, Carlomagno, Francesca, Romano, Alfredo, Bottaro, Donald P., Dathan, Nina A., Grieco, Michele, Fusco, Alfredo, Vecchio, Giancarlo, Maťoškovt̄, Brona, Kraus, Matthias H., Di Fiore, Pier Paolo

“…Multiple endocrine neoplasia types 2A and 2B (MEN2A and MEN2B) and familial medullary thyroid carcinoma are dominantly inherited cancer syndromes. All three…”
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Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 by Viparelli, Francesca, Doti, Nunzianna, Sandomenico, Annamaria, Marasco, Daniela, Dathan, Nina A., Miele, Claudia, Beguinot, Francesco, Monti, Simona M., Ruvo, Menotti

“…PLD’s (Phospholipases D) are ubiquitously expressed proteins involved in many transphosphatidylation reactions. They have a bi-lobed structure composed by two…”
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Protein-Protein Interactions: A Simple Strategy to Identify Binding Sites and Peptide Antagonists by Sandomenico, Annamaria, Monti, Simona M, Sabatella, Marco, De Capua, Antonia, Tornatore, Laura, Doti, Nunzianna, Viparelli, Francesca, Dathan, Nina A, Pedone, Carlo, Ruvo, Menotti, Marasco, Daniela

“…Secondary structure motifs and small protein domains can act as building blocks that are isolated and investigated to gain insights into protein global…”
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Functional analysis of mutant Xenopus U2 snRNAs by Hamm, J, Dathan, N A, Mattaj, I W

“…Methods for studying pre-mRNA splicing in Xenopus oocytes have been improved to allow simultaneous analysis of the splicing reaction and the formation of…”
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Only the Substitution of Methionine 918 with a Threonine and Not with Other Residues Activates RET Transforming Potential by Cirafici, Anna Maria, Salvatore, Giuliana, De Vita, Gabriella, Carlomagno, Francesca, Dathan, Nina A., Visconti, Roberta, Melillo, Rosa Marina, Fusco, Alfredo, Santoro, Massimo

“…Abstract Specific point-mutations of the RET receptor tyrosine kinase protooncogene are responsible for the inheritance of multiple endocrine neoplasia type 2A…”
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Ligand Stimulation of a Ret Chimeric Receptor Carrying the Activating Mutation Responsible for the Multiple Endocrine Neoplasia Type 2B by Rizzo, C, Califano, D, Colucci-D'Amato, G L, De Vita, G, D'Alessio, A, Dathan, N A, Fusco, A, Monaco, C, Santelli, G, Vecchio, G, Santoro, M, de Franciscis, V

“…Inherited activating mutations of Ret, a receptor tyrosine kinase, predispose to multiple endocrine neoplasia (MEN) types 2A and 2B and familial medullary…”
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Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma by Santoro, M, Dathan, N A, Berlingieri, M T, Bongarzone, I, Paulin, C, Grieco, M, Pierotti, M A, Vecchio, G, Fusco, A

“…The RET proto-oncogene encodes a transmembrane receptor of the tyrosine kinase family and has frequently been found activated in human thyroid carcinomas of…”
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Diversity in the Signals Required for Nuclear Accumulation of U snRNPs and Variety in the Pathways of Nuclear Transport by Fischer, Utz, Darzynkiewicz, Edward, Tahara, Stanley M., Dathan, Nina A., Lührmann, Reinhard, Mattaj, Iain W.

“…The requirements for nuclear targeting of a number of U snRNAs have been studied by analyzing the behavior of in vitro-generated transcripts after…”
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Changing the RNA polymerase specificity of U snRNA gene promoters by Mattaj, I W, Dathan, N A, Parry, H D, Carbon, P, Krol, A

“…The promoter of a Xenopus tropicalis U6 gene can be transcribed by both RNA polymerases II and III. Two distinct elements, a TATA-like sequence and the region…”
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The U2B″ RNP motif as a site of protein‐protein interaction by Scherly, D., Dathan, N. A., Boelens, W., Venrooij, W. J., Mattaj, I. W.

“…The U2 snRNP contains two specific proteins, U2B″ and U2A'. Neither of these proteins, on its own, is capable of specific interactions with U2 RNA. Here, a…”
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Activated RET/PTC oncogene elicits immediate early and delayed response genes in PC12 cells by Califano, D, Monaco, C, de Vita, G, D'Alessio, A, Dathan, N A, Possenti, R, Vecchio, G, Fusco, A, Santoro, M, de Franciscis, V

“…The expression of the receptor-like tyrosine kinase RET is associated with tumors, tissues or cell lines of neural crest origin. In addition RET products (Ret)…”
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A mutation in the RET proto-oncogene in Hirschsprung's disease affects the tyrosine kinase activity associated with multiple endocrine neoplasia type 2A and 2B by Cosma, M P, Panariello, L, Quadro, L, Dathan, N A, Fattoruso, O, Colantuoni, V

“…We demonstrate that a Hirschsprung (HSCR) mutation in the tyrosine kinase domain of the RET proto-oncogene abolishes in cis the tyrosine-phosphorylation…”
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Only the Substitution of Methionine 918 with a Threonine and Not with Other Residues Activates RET Transforming Potential1 by Cirafici, Anna Maria, Salvatore, Giuliana, De Vita, Gabriella, Carlomagno, Francesca, Dathan, Nina A, Visconti, Roberta, Melillo, Rosa Marina, Fusco, Alfredo, Santoro, Massimo

“…Specific point-mutations of the RET receptor tyrosine kinase protooncogene are responsible for the inheritance of multiple endocrine neoplasia type 2A (MEN2A)…”
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