Search Results - "Daskalova, Sasha M"
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The Biogenic Amine Tyramine and its Receptor (AmTyr1) in Olfactory Neuropils in the Honey Bee ( Apis mellifera ) Brain
Published in Frontiers in systems neuroscience (24-10-2017)“…This article describes the cellular sources for tyramine and the cellular targets of tyramine via the Tyramine Receptor 1 (AmTyr1) in the olfactory learning…”
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Biophysical Characterization of a Vaccine Candidate against HIV-1: The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a Maltose Binding Protein Fusion
Published in PloS one (21-08-2015)“…The membrane proximal region (MPR, residues 649-683) and transmembrane domain (TMD, residues 684-705) of the gp41 subunit of HIV-1's envelope protein are…”
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3
Suppression of lipopolysaccharide-induced inflammatory responses in RAW 264.7 murine macrophages by aqueous extract of Clinopodium vulgare L. (Lamiaceae)
Published in Journal of ethnopharmacology (10-12-2009)“…The wild basil Clinopodium vulgare L. is commonly used in Bulgarian folk medicine for treatment of irritated skin, mastitis- and prostatitis-related swelling,…”
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Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated proteins--towards development of a plant-based platform for production of protein therapeutics with mucin type O-glycosylation
Published in BMC biotechnology (24-08-2010)“…Mucin type O-glycosylation is one of the most common types of post-translational modifications that impacts stability and biological functions of many…”
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Interlocking activities of DNA polymerase β in the base excision repair pathway
Published in Proceedings of the National Academy of Sciences - PNAS (08-03-2022)“…SignificanceBase excision repair (BER) is one of the major DNA repair pathways used to fix a myriad of cellular DNA lesions. The enzymes involved in BER,…”
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Elongation Factor P Modulates the Incorporation of Structurally Diverse Noncanonical Amino Acids into Escherichia coli Dihydrofolate Reductase
Published in Journal of the American Chemical Society (01-11-2023)“…The introduction of noncanonical amino acids into proteins and peptides has been of great interest for many years and has facilitated the detailed study of…”
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Coronavirus envelope (E) protein remains at the site of assembly
Published in Virology (New York, N.Y.) (01-04-2015)“…Abstract Coronaviruses (CoVs) assemble at endoplasmic reticulum Golgi intermediate compartment (ERGIC) membranes and egress from cells in cargo vesicles. Only…”
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Study of the Lyase Activity of Human DNA Polymerase β Using Analogues of the Intermediate Schiff Base Complex
Published in Biochemistry (Easton) (08-05-2018)“…DNA polymerase β (Pol β) participates in mammalian base excision repair. The enzyme has a two-domain architecture, reflecting its dual functionality. The…”
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9
Protein Synthesis with Ribosomes Selected for the Incorporation of β‑Amino Acids
Published in Biochemistry (Easton) (16-06-2015)“…In an earlier study, β3-puromycin was used for the selection of modified ribosomes, which were utilized for the incorporation of five different β-amino acids…”
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Enhanced Binding Affinity for an i‑Motif DNA Substrate Exhibited by a Protein Containing Nucleobase Amino Acids
Published in Journal of the American Chemical Society (05-04-2017)“…Several variants of a nucleic acid binding motif (RRM1) of putative transcription factor hnRNP LL containing nucleobase amino acids at specific positions have…”
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An assay for DNA polymerase β lyase inhibitors that engage the catalytic nucleophile for binding
Published in Bioorganic & medicinal chemistry (01-09-2020)“…[Display omitted] DNA polymerase β (Pol β) repairs cellular DNA damage. When such damage is inflicted upon the DNA in tumor cells treated with DNA targeted…”
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Probing the Flexibility of the Catalytic Nucleophile in the Lyase Catalytic Pocket of Human DNA Polymerase β with Unnatural Lysine Analogues
Published in Biochemistry (Easton) (24-01-2017)“…DNA polymerase β (Pol β) is a key enzyme in mammalian base excision repair (BER), contributing stepwise 5′-deoxyribose phosphate (dRP) lyase and “gap-filling”…”
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Folbos, a new foldback element in rice [Oryza sativa]
Published in Genes & Genetic Systems (2005)“…A new class I foldback element, Folbos, has been discovered in O.sativa L. Its long terminal inverted repeats (IVRs) are 303 and 331 bp long and the left one…”
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Biophysical Characterization of a Vaccine Candidate against HIV-1: The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a Maltose Binding Protein Fusion: e0136507
Published in PloS one (01-08-2015)“…The membrane proximal region (MPR, residues 649-683) and transmembrane domain (TMD, residues 684-705) of the gp41 subunit of HIV-1's envelope protein are…”
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Journal Article