Search Results - "Dashner, Scott"
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Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence
Published in Clinical cancer research (15-07-2019)“…Up to 30% of patients with breast cancer relapse after primary treatment. There are no sensitive and reliable tests to monitor these patients and detect…”
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2
Chemoselective and Microwave-Assisted Synthesis of Glycopeptoids
Published in Organic letters (19-11-2009)“…The chemoselective glycosylation of N-alkylaminooxy side chains with unprotected reducing sugars has proven useful for the synthesis of glycopeptides. Herein,…”
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3
Synthesis of Aminooxy and N-Alkylaminooxy Amines for Use in Bioconjugation
Published in Journal of organic chemistry (20-08-2010)“…Five Boc-protected aminooxy and N-alkylaminooxy amines have been synthesized in 60−95% overall yield using a common synthetic strategy from readily available…”
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4
Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma
Published in Journal of clinical oncology (20-06-2019)“…Novel sensitive methods for early detection of relapse and for monitoring therapeutic efficacy may have a huge impact on risk stratification, treatment, and…”
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5
Circulating tumor DNA monitoring for early recurrence detection in epithelial ovarian cancer
Published in Gynecologic oncology (01-11-2022)“…Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. We examined the utility of circulating tumor DNA (ctDNA) as a prognostic biomarker…”
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Abstract 4542: Analytical validation of the SignateraTM RUO assay, a highly sensitive patient-specific multiplex PCR NGS-based noninvasive cancer recurrence detection and therapy monitoring assay
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Introduction: Liquid biopsy-based detection and monitoring of tumor-specific somatic mutations in cell-free DNA has great potential to improve patient…”
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Abstract P2-01-10: Detection of ctDNA following surgery predicts relapse in breast cancer patients receiving primary surgery
Published in Cancer research (Chicago, Ill.) (15-02-2022)“…Abstract Introduction: Identification of Molecular Residual Disease (MRD) by circulating tumour DNA (ctDNA) analysis has the potential to transform the…”
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Abstract 552: Circulating tumor DNA predicts disease recurrence in ovarian cancer patients
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Introduction: Epithelial ovarian, fallopian tube, and peritoneal cancer (EOC) is the most lethal gynecologic malignancy with a 5-year survival rate of…”
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Bespoke circulating tumor DNA (ctDNA) analysis as a predictive biomarker in solid tumor patients (pts) treated with single-agent pembrolizumab (P)
Published in Journal of clinical oncology (20-05-2019)“…Abstract only 2542 Background: Limited data exist in the clonal dynamics of serial ctDNA as a predictive biomarker in advanced solid tumor pts receiving immune…”
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Abstract 913: Early detection of metastatic relapse and monitoring of therapeutic efficacy by ultra-deep sequencing of plasma cell-free DNA in patients with urothelial bladder carcinoma
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Background Circulating tumor DNA (ctDNA) analysis is an emerging field for diagnosis, monitoring of treatment efficacy and detection of disease…”
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Abstract 1590: Personalized circulating tumor DNA analysis to monitor colorectal cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Early detection of disease recurrence has shown to improve survival in patients with early-stage colorectal cancer (CRC) (Pita-Fernandez et al.,…”
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Examination of Lygus Bug Resistance in Lima Bean: Polygalacturonase Inhibiting Proteins as Candidate Traits
Published 01-01-2018“…This thesis research examines the role of polygalacturonase inhibiting proteins (PGIPs) in the resistance of lima bean (Phaseolus lunatus ) to the lygus bug…”
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Dissertation