Search Results - "Dashkova, Natalia S."
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Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with Monoconjugates
Published in International journal of molecular sciences (01-07-2023)“…Prostate cancer is the second most common cancer among men. We designed and synthesized new ligands targeting prostate-specific membrane antigen and suitable…”
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Optimization of the dipeptide motifs in the PSMA ligands linker structure: synthesis and in vitro evaluation
Published in Medicinal chemistry research (2023)“…An improved series of ligands targeting prostatic specific membrane antigen has been reported. Varying compounds and their biological parameters were due to…”
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Synthesis and initial in vitro evaluation of PSMA-targeting ligands with a modified aromatic moiety at the lysine ε-nitrogen atom
Published in Bioorganic & medicinal chemistry letters (01-09-2022)“…[Display omitted] We report an improved series of ligands targeting prostate specific membrane antigen (PSMA). The new compounds were designed by the…”
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Thiourea Modified Doxorubicin: A Perspective pH-Sensitive Prodrug
Published in Bioconjugate chemistry (20-03-2019)“…A novel approach to the synthesis of pH-sensitive prodrugs has been proposed: thiourea drug modification. Resulting prodrugs can release the cytotoxic agent…”
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Choice of the optimal synthetic approach for the polypeptide ligands of prostatic specific membrane antigen preparation
Published in Mendeleev communications (01-07-2023)“…[Display omitted] Two alternative synthetic schemes involving solid-phase peptide synthesis steps for the preparation of prostatic specific membrane antigen…”
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