Search Results - "Dash, Ranjan"
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A size‐modified poisson–boltzmann ion channel model in a solvent of multiple ionic species: Application to voltage‐dependent anion channel
Published in Journal of computational chemistry (30-01-2020)“…We present a new size‐modified Poisson–Boltzmann ion channel (SMPBIC) model and use it to calculate the electrostatic potential, ionic concentrations, and…”
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Mechanistic characterization of the thioredoxin system in the removal of hydrogen peroxide
Published in Free radical biology & medicine (01-01-2015)“…The thioredoxin system, which consists of a family of proteins, including thioredoxin (Trx), peroxiredoxin (Prx), and thioredoxin reductase (TrxR), plays a…”
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A Bibliometric Analysis of Climate Investing
Published in International journal of energy economics and policy (17-05-2023)“…This research article seeks to provide a comprehensive review of climate investing and anticipated future developments by using bibliometric study. Climate…”
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4
miR-21-5p regulates mitochondrial respiration and lipid content in H9C2 cells
Published in American journal of physiology. Heart and circulatory physiology (01-03-2019)“…Cardiovascular-related pathologies are the single leading cause of death in patients with chronic kidney disease (CKD). Previously, we found that a 5/6th…”
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Simple accurate mathematical models of blood HbO2 and HbCO2 dissociation curves at varied physiological conditions: evaluation and comparison with other models
Published in European journal of applied physiology (2016)“…Purpose Equations for blood oxyhemoglobin (HbO 2 ) and carbaminohemoglobin (HbCO 2 ) dissociation curves that incorporate nonlinear biochemical interactions of…”
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Elucidating the roles of solubility and ventilation-perfusion mismatch in the second gas effect using a two-step model of gas exchange
Published in Journal of applied physiology (1985) (01-06-2020)“…The second gas effect occurs when high inspired concentrations of a first gas, usually nitrous oxide, enhance the uptake of other gases administered…”
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Effects of ROS pathway inhibitors and NADH and FADH2 linked substrates on mitochondrial bioenergetics and ROS emission in the heart and kidney cortex and outer medulla
Published in Archives of biochemistry and biophysics (01-08-2023)“…Mitochondria are major sources of reactive oxygen species (ROS), which play important roles in both physiological and pathological processes. However, the…”
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Network mechanisms and dysfunction within an integrated computational model of progression through mitosis in the human cell cycle
Published in PLoS computational biology (06-04-2020)“…The cellular protein-protein interaction network that governs cellular proliferation (cell cycle) is highly complex. Here, we have developed a novel…”
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Integrated computational model of the bioenergetics of isolated lung mitochondria
Published in PloS one (11-06-2018)“…Integrated computational modeling provides a mechanistic and quantitative framework for describing lung mitochondrial bioenergetics. Thus, the objective of…”
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Mitochondrial function in lungs of rats with different susceptibilities to hyperoxia-induced acute lung injury
Published in Journal of applied physiology (1985) (01-08-2024)“…Adult rats exposed to hyperoxia (>95% O ) die from respiratory failure in 60-72 h. However, rats preconditioned with >95% O for 48 h followed by 24 h in room…”
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Quantification of mitochondrial membrane potential in the isolated rat lung using rhodamine 6G
Published in Journal of applied physiology (1985) (01-04-2020)“…Mitochondrial membrane potential (Δψ ) plays a key role in vital mitochondrial functions, and its dissipation is a hallmark of mitochondrial dysfunction. The…”
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Inhibition of mTORC2 promotes natriuresis in Dahl salt-sensitive rats via the decrease of NCC and ENaC activity
Published in American journal of physiology. Renal physiology (01-09-2024)“…We have previously observed that prolonged administration of rapamycin, an inhibitor targeting the mammalian target of rapamycin complex (mTORC)1, partially…”
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Substrate-dependent differential regulation of mitochondrial bioenergetics in the heart and kidney cortex and outer medulla
Published in Biochimica et biophysica acta. Bioenergetics (01-02-2022)“…The kinetics and efficiency of mitochondrial oxidative phosphorylation (OxPhos) can depend on the choice of respiratory substrates. Furthermore, potential…”
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Effect of net gas volume changes on alveolar and arterial gas partial pressures in the presence of ventilation-perfusion mismatch
Published in Journal of applied physiology (1985) (01-03-2019)“…The second gas effect (SGE) occurs when nitrous oxide enhances the uptake of volatile anesthetics administered simultaneously. Recent work shows that the SGE…”
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Computational Modeling of Substrate‐Dependent Differential Regulation of Mitochondrial Bioenergetics in the Heart and Kidney Cortex and Outer Medulla
Published in The FASEB journal (01-05-2022)“…Rationale It is recognized that the kinetics and efficiency of mitochondrial O2 consumption for ATP production depend on the choice of respiratory substrates…”
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Changes in Oxygen Consumption and Metabolomic Profiles in the Kidney of Sprague‐Dawley Rat fed a High‐Salt Diet
Published in The FASEB journal (01-05-2022)“…The metabolism of oxygen and substrates in the kidney under normal conditions and in salt‐sensitive hypertension is still not well understood. A novel method…”
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Substrate‐Dependent Differential Regulation of Mitochondrial Bioenergetics and ROS emission in the Heart and Kidney Cortex and Outer Medulla
Published in The FASEB journal (01-05-2022)“…Rationale The kinetics and efficiency of mitochondrial oxidative phosphorylation (OxPhos) is determined by the availability and utilization of particular…”
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Reverse Electron Transfer is a More Dominant Source of Mitochondrial ROS Production in the Heart and Kidney Outer Medulla than in the Kidney Cortex
Published in The FASEB journal (01-05-2022)“…Rationale Reactive oxygen species (ROS; e.g. O2·– and H2O2) play important roles in both physiological and pathophysiological processes. ROS in low…”
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Assessment of Mitochondrial Respiratory Function in Isolated Nephron Segments of Dahl SS Rats in Salt Induced Hypertension
Published in The FASEB journal (01-05-2022)“…Rationale Kidney nephrons actively reabsorb 99% of the filtrate to maintain body fluid and solute homeostasis. A large amount of ATP synthesis and O2…”
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Synaptic and mitochondrial mechanisms behind alcohol-induced imbalance of excitatory/inhibitory synaptic activity and associated cognitive and behavioral abnormalities
Published in Translational psychiatry (22-01-2024)“…Alcohol consumption during pregnancy can significantly impact the brain development of the fetus, leading to long-term cognitive and behavioral problems…”
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