Search Results - "Das S., Syam"

All Trans Retinoic Acid Attenuates Markers of Neuroinflammation in Rat Brain by Modulation of SIRT1 and NFκB by Priyanka, S. H., Syam Das, S., Thushara, A. J., Rauf, Arun A., Indira, M.

“…Alcohol abuse affects several neurological pathways and causes significant alterations in the brain. Abstention from alcohol causes only a marginal decrease in…”
Get full text

The effects of oral administration of curcumin-galactomannan complex on brain waves are consistent with brain penetration: a randomized, double-blinded, placebo-controlled pilot study by Khanna, Aman, Das S, Syam, Kannan, R., Swick, Andrew G., Matthewman, Cristina, Maliakel, Balu, Ittiyavirah, Sibi P., Krishnakumar, I. M.

“…A novel highly bioavailable curcumin-galactomannan (CGM) formulation was shown to have improved blood-brain-barrier (BBB) permeability of free curcuminoids in…”
Get full text

Natural self‐emulsifying reversible hybrid‐hydrogel delivery (N'SERH) of tocopherol enhances bioavailability and modulates alcohol‐induced reproductive toxicity in rats by Vismaya, K. U., Noorjasmine, T. N., Syam Das, S., Kesavan, Lakshmi, Baby Chakrapani, P. S., Krishnakumar, I. M., Kumar, C. V. Sreeranjit

“…Alpha‐tocopherol (α‐Toc), an antioxidant vitamin, has been widely prescribing in the treatment of infertility, in spite of its limited oral bioavailability…”
Get full text

Atorvastatin improves Y-maze learning behaviour in nicotine treated male albino rats by Das S., Syam, Nair, Saritha S., Kavitha, S., Febi, John, Indira, M.

“…Nicotine is a parasympathomimetic alkaloid present in tobacco which can induce hyperlipidemia and has a direct effect on neural functions. Statins, competitive…”
Get full text

Atorvastatin modulates drug transporters and ameliorates nicotine‐induced testicular toxicity by Syam Das, S., Nair, S. S., Indira, M.

“…Summary We studied the changes in mRNA expressions of influx and efflux transporters, blood–testis–barrier proteins (BTB) and key apoptotic genes in the testis…”
Get full text

Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study by K, Mamatha, Aryan, Manu Kanjoormana, Prabhakaran, Prathibha, Mulakal, Johannah Natinga, Das S, Syam, Im, Krishnakumar, Parameswara Panicker, Sreejith

“…Allergic rhinitis (AR) is an IgE-mediated reaction to inhaled allergens, and is a prominent health concern affecting approximately 400 million people…”
Get full text

Corrigendum: A natural sustained-intestinal release formulation of red chili pepper extracted capsaicinoids (Capsifen ® ) safely modulates energy balance and endurance performance: a randomized, double-blind, placebo-controlled study by Roopashree, N, Syam, Das S, Krishnakumar, I M, Mala, K N, Fleenor, Bradley S, Thomas, Jestin

“…[This corrects the article DOI: 10.3389/fnut.2024.1348328.]…”
Get full text

A natural sustained-intestinal release formulation of red chili pepper extracted capsaicinoids (Capsifen®) safely modulates energy balance and endurance performance: a randomized, double-blind, placebo-controlled study by Roopashree, N, Syam, Das S, Krishnakumar, I M, Mala, K N, Fleenor, Bradley S, Thomas, Jestin

“…Overweight and obesity are major public health concerns, with a sharp increase in prevalence over the last few decades. The primary cause is an imbalance…”
Get full text

Exploring the short-term influence of a proprietary oil extract of black cumin ( Nigella sativa ) on non-restorative sleep: a randomized, double-blinded, placebo-controlled actigraphy study by Mohan, M E, Mohan, Mohind C, Prabhakaran, Prathibha, Syam Das, S, Krishnakumar, I M, Baby Chakrapani, P S

“…(black cumin, or black seed) is popularly known as the seed of blessings in the Arab system of medicine. Though not widely recommended for sleep, a unique…”
Get full text

Corrigendum: Exploring the short-term influence of a proprietary oil extract of black cumin ( Nigella sativa ) on non-restorative sleep: a randomized, double-blinded, placebo-controlled actigraphy study by Mohan, M E, Mohan, Mohind C, Prabhakaran, Prathibha, Das, S Syam, Krishnakumar, I M, Chakrapani, P S Baby

“…[This corrects the article DOI: 10.3389/fnut.2023.1200118.]…”
Get full text

All trans retinoic acid modulates TNF-α and CYP2E1 pathways and enhances regression of ethanol-induced fibrosis markers in hepatocytes and HSCs in abstaining rodent model by Priyanka, S. H., Syam Das, S., Nair, Saritha S., Rauf, Arun A., Indira, M.

“…Context: Our previous studies showed that all trans retinoic acid (ATRA) ameliorates alcohol-induced toxicity. Hence, we evaluated the efficacy of ATRA and…”
Get full text

All trans retinoic acid (ATRA) mediated modulation of N-methyl D-aspartate receptor (NMDAR) and Kruppel like factor 11 (KLF11) expressions in the mitigation of ethanol induced alterations in the brain by Nair, Saritha S., Prathibha, P., Syam Das, S., Kavitha, S., Indira, M.

“…•Chronic alcohol administration caused neurotoxicity.•ATRA supplementation ameliorated alcohol induced neurotoxicity.•It reduced oxidative stress.•Upregulated…”
Get full text

Protective effect of ascorbic acid against ethanol-induced reproductive toxicity in male guinea pigs by Harikrishnan, R., Abhilash, P. A., Syam Das, S., Prathibha, P., Rejitha, S., John, Febi, Kavitha, S., Indira, M.

“…The present study was undertaken to elucidate the effect of ascorbic acid on alcohol-induced reproductive toxicity and also to compare it with that of…”
Get full text

Safety assessment of a fenugreek dietary fiber-based formulation of capsaicinoids-rich red chili (Capsicum annum) extract (Capsifen®): Acute and sub-chronic studies by Joseph, Ashil, NM, Johannah, Kumar, Suresh, S, Syam Das, Maliakel, Balu, IM, Krishnakumar

“…Despite the promising health beneficial effects (thermogenic, lipolytic, hypotriglyceridemic, hypocholesterolemic, anti-inflammatory and anticancer) of…”
Get full text

Additive effect of alpha-tocopherol and ascorbic acid in combating ethanol-induced hepatic fibrosis by Prathibha, P, Rejitha, S, Harikrishnan, R, Das, S Syam, Abhilash, P A, Indira, M

“…Objective To investigate the efficacy of combined administration of alpha-tocopherol (AT) and ascorbic acid (AA) in reducing ethanol-induced hepatotoxicity…”
Get full text

Brain regional pharmacokinetics following the oral administration of curcumagalactomannosides and its relation to cognitive function by Kannan, Ramalingam G., Abhilash, Maliakal B., Dinesh, Kumar, Syam, Das S., Balu, Maliakel, Sibi, Ittiyavirah, Krishnakumar, I. M.

“…Though a number of bioavailable formulations of curcuminoids have been reported and available commercially as nutraceuticals for brain health, systematic…”
Get full text

Exploring the possibility of a proprietary black cumin oil extract as a Dual Orexin Receptor Antagonist in restoring stress-sleep balance on stress-induced sleep deprived animals by OR, Saneha, Krishna, Priya, Das S, Syam, IM, Krishnakumar, Joseph, Litty

“…Orexins act as a molecular switch for the release of cortisol/corticosterone in response to a stress stimulus and hence to regulate sleep/wake cycle. Orexin…”
Get full text

Oral bioavailability and neuroprotective effect of a novel food-grade formulation of fisetin using fenugreek-galactomannan hydrogel scaffolds by Athira, K., Syam Das, S., Swick, Andrew, Krishnakumar, I.M., Abdul Vahab, A.

“…Despite the beneficial pharmacological effects, poor oral bioavailability limits the nutritional efficacy of fisetin, a dietary flavonoid. To this end, herein…”
Get full text

Safety and Efficacy of Ferula asafoetida in Functional Dyspepsia: A Randomized, Double-Blinded, Placebo-Controlled Study by Maliakel, Balu, Syam, Das S., Thomas, Jestin, Mala, K. N., Krishnakumar, I. M.

“…Despite the availability of various synthetic drugs for the treatment of functional dyspepsia (FD), the side effects and their cost have always created a great…”
Get full text

Supplementation of all trans retinoic acid ameliorates ethanol-induced endoplasmic reticulum stress by Nair, Saritha S, Das S, Syam, Nair, Reshma P, Indira, M

“…Molecular pathogenesis of chronic alcoholism is linked to increased endoplasmic reticulum stress. Ethanol is a competitive inhibitor of vitamin A metabolism…”
Get full text