Search Results - "Das Gupta, Ruchira"

Structures of Adnectin/Protein Complexes Reveal an Expanded Binding Footprint by Ramamurthy, Vidhyashankar, Krystek, Stanley R., Bush, Alexander, Wei, Anzhi, Emanuel, Stuart L., Das Gupta, Ruchira, Janjua, Ahsen, Cheng, Lin, Murdock, Melissa, Abramczyk, Bozena, Cohen, Daniel, Lin, Zheng, Morin, Paul, Davis, Jonathan H., Dabritz, Michael, McLaughlin, Douglas C., Russo, Katie A., Chao, Ginger, Wright, Martin C., Jenny, Victoria A., Engle, Linda J., Furfine, Eric, Sheriff, Steven

“…Adnectins are targeted biologics derived from the tenth type III domain of human fibronectin (10Fn3), a member of the immunoglobulin superfamily…”
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Molecular definition of the 22q11 deletions in velo-cardio-facial syndrome by MORROW, B, GOLDBERG, R, RAJU KUCHERLAPATI, CARLSON, C, RUCHIRA DAS GUPTA, SIROTKIN, H, COLLINS, J, DUNHAM, I, O'DONNELL, H, SCAMBLER, P, SHPRINTZEN, R

“…Velo-cardio-facial syndrome (VCFS) is a common genetic disorder among individuals with cleft palate and is associated with hemizygous deletions in human…”
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Developing Adnectins That Target SRC Co-Activator Binding to PXR: A Structural Approach toward Understanding Promiscuity of PXR by Khan, Javed A., Camac, Daniel M., Low, Simon, Tebben, Andrew J., Wensel, David L., Wright, Martin C., Su, Julie, Jenny, Victoria, Gupta, Ruchira Das, Ruzanov, Max, Russo, Katie A., Bell, Aneka, An, Yongmi, Bryson, James W., Gao, Mian, Gambhire, Pallavi, Baldwin, Eric T., Gardner, Daniel, Cavallaro, Cullen L., Duncia, John V., Hynes, John

“…The human pregnane X receptor (PXR) is a promiscuous nuclear receptor that functions as a sensor to a wide variety of xenobiotics and regulates expression of…”
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Identification, Characterization, and Precise Mapping of a Human Gene Encoding a Novel Membrane-Spanning Protein from the 22q11 Region Deleted in Velo–Cardio–Facial Syndrome by Sirotkin, Howard, Morrow, Bernice, Saint-Jore, Bruno, Puech, Anne, Gupta, Ruchira Das, Patanjali, Sankhavaram R., Skoultchi, Arthur, Weissman, Sherman M., Kucherlapati, Raju

“…Velo–cardio–facial syndrome (VCFS) and DiGeorge syndrome (DGS) are characterized by a wide spectrum of phenotypes including cleft palate, conotruncal heart…”
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Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity by Mangan, Paul R, Su, Linhui Julie, Jenny, Victoria, Tatum, Andrea L, Picarillo, Caryn, Skala, Stacey, Ditto, Noah, Lin, Zheng, Yang, XiaoXia, Cotter, Pete Z, Shuster, David J, Song, Yunling, Borowski, Virna, Thomas, Rochelle L, Heimrich, Elizabeth M, Devaux, Brigitte, Das Gupta, Ruchira, Carvajal, Irvith, McIntyre, Kim W, Xie, Jenny, Zhao, Qihong, Struthers, Mary, Salter-Cid, Luisa M

“…Therapies targeting either interleukin (IL)-23 or IL-17 have shown promise in treating T helper 17 (Th17)-driven autoimmune diseases. Although IL-23 is a…”
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A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptor by Emanuel, Stuart L., Engle, Linda J., Chao, Ginger, Zhu, Rong-Rong, Cao, Carolyn, Lin, Zheng, Yamniuk, Aaron P., Hosbach, Jennifer, Brown, Jennifer, Fitzpatrick, Elizabeth, Gokemeijer, Jochem, Morin, Paul, Morse, Brent A., Carvajal, Irvith M., Fabrizio, David, Wright, Martin C., Das Gupta, Ruchira, Gosselin, Michael, Cataldo, Daniel, Ryseck, Rolf P., Doyle, Michael L., Wong, Tai W., Camphausen, Raymond T., Cload, Sharon T., Marsh, H. Nicholas, Gottardis, Marco M., Furfine, Eric S.

“…Engineered domains of human fibronectin (Adnectins™) were used to generate a bispecific Adnectin targeting epidermal growth factor receptor (EGFR) and…”
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Germ-line msh6 mutations in colorectal cancer families by KOLODNER, R. D, TYTELL, J. D, GARBER, J. E, SYNGAL, S, ANTON-CULVER, H, LI, F. P, SCHMEITS, J. L, KANE, M. F, GUPTA, R. D, WEGER, J, WAHLBERG, S, FOX, E. A, PEEL, D, ZIOGAS, A

“…Hereditary nonpolyposis colorectal carcinoma (HNPCC) is due primarily to inherited mutations in two mismatch repair genes, MSH2 and MLH1, whereas germ-line…”
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Dominant Saccharomyces cerevisiae msh6 Mutations Cause Increased Mispair Binding and Decreased Dissociation from Mispairs by Msh2-Msh6 in the Presence of ATP by Hess, Martin T., Gupta, Ruchira Das, Kolodner, Richard D.

“…A previous study described four dominantmsh6 mutations that interfere with both the Msh2-Msh6 and Msh2-Msh3 mismatch recognition complexes (Das Gupta, R., and…”
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Novel dominant mutations in Saccharomyces cerevisiae MSH6 by Kolodner, Richard D, Das Gupta, Ruchira

“…Inherited mutations in the mismatch repair (MMR) genes MSH2 and MLH1 are found in most hereditary nonpolyposis colon cancer (HNPCC) patients studied…”
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A global benchmark study using affinity-based biosensors by Rich, Rebecca L., Papalia, Giuseppe A., Flynn, Peter J., Quinn, John, Waddell, M. Brent, Scott, Michael, Thompson, Joshua, Berlier, Judie, Corry, Schuyler, Baltzinger, Mireille, Schoenemann, Andreas, Wieckowski, Sebastien, Page, Phillip, Ryan, Thomas E., Duffner, Jay, Ganguly, Tanmoy, Corbin, John, Gautam, Satyen, Anderluh, Gregor, Bavdek, Andrej, Reichmann, Dana, Yadav, Satya P., Pol, Ewa, Drake, Andrew, Miller, Ken, Schuman, Jason, Lindquist, Kevin, Herlihy, Kara, Brandani, Pietro, Terwey, Danny, Darling, Ryan J., Wang, Liann, Liu, Yang, Abdiche, Yasmina, Malashock, Daniel, Wong, Melanie, Lafer, Eileen, Hinck, Cynthia, Thompson, Kevin, Primo, Carmelo Di, Joyce, Alison, Torta, Federico, Bagge Hagel, Anne Birgitte, Krarup, Janus, Ferreira, Monica, Shikov, Sergei, Mikolajczyk, Malgorzata, Abe, Yuki, Giannetti, Anthony M., Krishnamoorthy, Ganeshram, Beusink, Bianca, Satpaev, Daulet, Tsang, Tiffany, Fang, Eric, Pritsch, Otto, Obal, Gonzalo, Nilapwar, Sanjay, Busby, Ben, Gutierrez-Sanchez, Gerardo, Canepa, Sylvie, Witte, Krista, Cho, Yun Hee, D’Agata, Roberta, Calvert, Rosy, Hernaiz, Maria Jose, Bravman, Tsafir, Dines, Monica, Yang, Min-Hsiang, Li, Jiejin, Wear, Martin, Grinberg, Asya, Dolezal, Olan, Gainey, Melicia, Anderson, Henrik, Peng, Jinlin, Lewis, Mark, Spies, Peter, Trinh, Quyhn, Bibikov, Sergei, Raymond, Jill, Chandrasekaran, Vidya, Guimaraes, Rejane, Hughes, Heather, Mantz, Hubert, Skrabana, Rostislav, Witmer, Mark, Skladal, Petr, Korza, George, Khadir, Abdelkrim, Podlaski, Frank, Rothacker, Julie, Rafique, Ashique, Dankbar, Nico, Vuyisich, Momchilo, Uren, Aykut, Kalyuzhniy, Oleksandr, Lewis, Kenneth, Chomey, Eugene, Pak, Brian J., Myszka, David G.

“…To explore the variability in biosensor studies, 150 participants from 20 countries were given the same protein samples and asked to determine kinetic rate…”
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Developing Adnectins That Target SRC Co-Activator Binding to PXR: A Structural Approach toward Understanding Promiscuity of PXR by Khan, Javed A., Camac, Daniel M., Low, Simon, Tebben, Andrew J., Wensel, David L., Wright, Martin C., Su, Julie, Jenny, Victoria, Gupta, Ruchira Das, Ruzanov, Max, Russo, Katie A., Bell, Aneka, An, Yongmi, Bryson, James W., Gao, Mian, Gambhire, Pallavi, Baldwin, Eric T., Gardner, Daniel, Cavallaro, Cullen L., Duncia, John V., Hynes, Jr., John

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An Integrated Approach for Identifying and Mapping Human Genes by Gupta, Ruchira Das, Morrow, Bernice, Marondel, Ivonne, Parimoo, Satish, Goei, Vita L., Gruen, Jeffrey, Weissman, Sherman, Skoultchi, Arthur, Kuchrlapati, Raju

“…We have developed a method for generating expressed-sequence maps of human chromosomes. The method involves several steps that begin with libraries of highly…”
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Saccharomyces cerevisiae pms2 mutations are alleles of MLH1, and pms2-2 corresponds to a hereditary nonpolyposis colorectal carcinoma-causing missense mutation by Jeyaprakash, A., Gupta, Ruchira Das, Kolodner, Richard

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Towards a genetic definition of velo-cardio-facial syndrome by Das Gupta, Ruchira

“…Velo-cardio-facial syndrome (VCFS) is a relatively common genetic disorder, characterized by clefting of the palate, cardiac anomalies, pharyngeal…”
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