Search Results - "Das, Priyojit"

Characterizing the variation in chromosome structure ensembles in the context of the nuclear microenvironment by Das, Priyojit, Shen, Tongye, McCord, Rachel Patton

“…Inside the nucleus, chromosomes are subjected to direct physical interaction between different components, active forces, and thermal noise, leading to the…”
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Inferring chromosome radial organization from Hi-C data by Das, Priyojit, Shen, Tongye, McCord, Rachel Patton

“…The nonrandom radial organization of eukaryotic chromosome territories (CTs) inside the nucleus plays an important role in nuclear functional…”
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Loops, topologically associating domains, compartments, and territories are elastic and robust to dramatic nuclear volume swelling by Sanders, Jacob T., Golloshi, Rosela, Das, Priyojit, Xu, Yang, Terry, Peyton H., Nash, Darrian G., Dekker, Job, McCord, Rachel Patton

“…Layers of genome organization are becoming increasingly better characterized, but less is known about how these structures respond to perturbation or shape…”
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Differential contributions of nuclear lamina association and genome compartmentalization to gene regulation by Das, Priyojit, San Martin, Rebeca, McCord, Rachel Patton

“…Chromatin regions that interact with the nuclear lamina are often heterochromatic, repressed in gene expression, and in the spatial B compartment. However,…”
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Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression by San Martin, Rebeca, Das, Priyojit, Dos Reis Marques, Renata, Xu, Yang, Roberts, Justin M, Sanders, Jacob T, Golloshi, Rosela, McCord, Rachel Patton

“…Prostate cancer aggressiveness and metastatic potential are influenced by gene expression and genomic aberrations, features that can be influenced by the 3D…”
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Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification by San Martin, Rebeca, Das, Priyojit, Sanders, Jacob T, Hill, Ashtyn M, McCord, Rachel Patton

“…The expression of a mutant Lamin A, progerin, in Hutchinson-Gilford Progeria Syndrome leads to alterations in genome architecture, nuclear morphology,…”
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Node features of chromosome structure networks and their connections to genome annotation by Xu, Yingjie, Das, Priyojit, McCord, Rachel Patton, Shen, Tongye

“…The 3D conformations of chromosomes can encode biological significance, and the implications of such structures have been increasingly appreciated recently…”
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SMILE: mutual information learning for integration of single-cell omics data by Xu, Yang, Das, Priyojit, McCord, Rachel Patton

“…Abstract Motivation Deep learning approaches have empowered single-cell omics data analysis in many ways and generated new insights from complex cellular…”
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Quantifying variation in chromosome structural ensembles using statistical analysis of pairwise structure similarity matrices by Das, Priyojit, Shen, Tongye, McCord, Rachel P.

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Chromosome compartmentalization: causes, changes, consequences, and conundrums by Li, Heng, Playter, Christopher, Das, Priyojit, McCord, Rachel Patton

“…Genome compartments are shaped by epigenetic marks and nuclear structure tethering.The most dramatic compartment changes occur during cell differentiation or…”
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Symmetry-Engineered BINOL-Based Porous Aromatic Frameworks for H 2 O 2 Production via Artificial Photosynthesis and In Situ Degradation of Pharmaceutical Pollutants by Banerjee, Flora, Gupta, Priyojit Das, Roy, Shiladitya, Samanta, Suman Kalyan

“…Accomplishing visible light-driven H O production at millimolar concentrations is practically challenging, particularly for organic semiconductors. In this…”
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Symmetry-Engineered BINOL-Based Porous Aromatic Frameworks for H2O2 Production via Artificial Photosynthesis and In Situ Degradation of Pharmaceutical Pollutants by Banerjee, Flora, Gupta, Priyojit Das, Roy, Shiladitya, Samanta, Suman Kalyan

“…Accomplishing visible light-driven H2O2 production at millimolar concentrations is practically challenging, particularly for organic semiconductors. In this…”
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SnapShot: Chromosome organization by McCord, Rachel Patton, Xu, Yang, Li, Heng, Das, Priyojit, San Martin, Rebeca

“…Chromosomes in higher eukaryotes are folded at different length scales into loop extrusion domains, spatial compartments, and chromosome territories and…”
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Inferring Radial Organization of Chromosomal Territories from HI-C Data by Das, Priyojit, Sanders, Jacob T., Shen, Tongye, McCord, Rachel P.

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Abstract 2033: Rearrangement of the 3D genome structure in prostate cancer is a potential mechanism for disease exacerbation and classifies cancers according to progression by Martin, Rebeca San, Das, Priyojit, Marques, Renata Dos Reis, McCord, Rachel P.

“…Prostate cancer (PCa) aggressiveness and propensity to metastasize can be influenced by gene expression patterns, genomic aberrations, and overall cellular and…”
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Constricted migration is associated with stable 3D genome structure differences in cancer cells by Golloshi, Rosela, Playter, Christopher, Freeman, Trevor F, Das, Priyojit, Raines, Thomas Isaac, Garretson, Joshua H, Thurston, Delaney, McCord, Rachel Patton

“…To spread from a localized tumor, metastatic cancer cells must squeeze through constrictions that cause major nuclear deformations. Since chromosome structure…”
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Abstract A061: Nuclear lamin content as a biomarker for prostate cancer progression by Martin, Rebeca San, Das, Priyojit, Hossain, Sanaz, McCord, Rachel Patton

“…Lamins are proteins that help to structure the cellular nucleus via the formation of an intermediate filament weave that grants rigidity to the nuclear…”
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Using contact statistics to characterize structure transformation of biopolymer ensembles by Das, Priyojit, Golloshi, Rosela, McCord, Rachel Patton, Shen, Tongye

“…As a unique subset of functional polymers, many biopolymers have a set of well-defined three-dimensional (3D) structural characteristics that can be described…”
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A novel SFLA based method for gene expression biclustering by Das, Priyojit, Saha, Sujay

“…Form the time of its invention, microarray technology is continuously growing and has been taking major role in biological research. This technology generates…”
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Gene Ranking: A Novel Approach Using Multi-Objective Genetic Algorithm by Das, Priyojit, Saha, Sujay, Ghosh, Anupam, Dey, Kashi Nath

“…In a Gene Co-expression Network, the same or closely related genes are clustered into co-expressed groups. It is necessary to investigate the role that these…”
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