Search Results - "Das, Nitin A"

Empagliflozin reduces high glucose-induced oxidative stress and miR-21-dependent TRAF3IP2 induction and RECK suppression, and inhibits human renal proximal tubular epithelial cell migration and epithelial-to-mesenchymal transition by Das, Nitin A., Carpenter, Andrea J., Belenchia, Anthony, Aroor, Annayya R., Noda, Makoto, Siebenlist, Ulrich, Chandrasekar, Bysani, DeMarco, Vincent G.

“…Proximal tubular epithelial cells (PTEC) in the S1 segment of the kidney abundantly express sodium-glucose co-transporters (SGLT) that play a critical role in…”
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Glycemic control by the SGLT2 inhibitor empagliflozin decreases aortic stiffness, renal resistivity index and kidney injury by Aroor, Annayya R, Das, Nitin A, Carpenter, Andrea J, Habibi, Javad, Jia, Guanghong, Ramirez-Perez, Francisco I, Martinez-Lemus, Luis, Manrique-Acevedo, Camila M, Hayden, Melvin R, Duta, Cornel, Nistala, Ravi, Mayoux, Eric, Padilla, Jaume, Chandrasekar, Bysani, DeMarco, Vincent G

“…Arterial stiffness is emerging as an independent risk factor for the development of chronic kidney disease. The sodium glucose co-transporter 2 (SGLT2)…”
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RECK suppresses interleukin‐17/TRAF3IP2‐mediated MMP‐13 activation and human aortic smooth muscle cell migration and proliferation by Mummidi, Srinivas, Das, Nitin A., Carpenter, Andrea J., Yoshida, Tadashi, Yariswamy, Manjunath, Mostany, Ricardo, Izadpanah, Reza, Higashi, Yusuke, Sukhanov, Sergiy, Noda, Makoto, Siebenlist, Ulrich, Rector, Randy S., Chandrasekar, Bysani

“…Sustained inflammation and matrix metalloproteinase (MMP) activation contribute to vascular occlusive/proliferative disorders. Interleukin‐17 (IL‐17) is a…”
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TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart by Das, Nitin A., Carpenter, Andrea J., Yoshida, Tadashi, Kumar, Senthil A., Gautam, Sandeep, Mostany, Ricardo, Izadpanah, Reza, Kumar, Ashok, Mummidi, Srinivas, Siebenlist, Ulrich, Chandrasekar, Bysani

“…Persistent inflammation promotes development and progression of heart failure (HF). TWEAK (TNF-Related WEAK Inducer Of Apoptosis), a NF-κB- and/or…”
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The combination of a neprilysin inhibitor (sacubitril) and angiotensin-II receptor blocker (valsartan) attenuates glomerular and tubular injury in the Zucker Obese rat by Habibi, Javad, Aroor, Annayya R, Das, Nitin A, Manrique-Acevedo, Camila M, Johnson, Megan S, Hayden, Melvin R, Nistala, Ravi, Wiedmeyer, Charles, Chandrasekar, Bysani, DeMarco, Vincent G

“…Diabetic nephropathy (DN) is characterized by glomerular and tubulointerstitial injury, proteinuria and remodeling. Here we examined whether the combination of…”
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Where are they now? An analysis of integrated cardiothoracic surgery residency applicants by Worrell, Christopher M., Das, Nitin A., Sako, Edward Y.

“…Changes in cardiothoracic surgery (CTS) workforce trends have affected training paradigms to include the establishment of integrated six-year CTS residency…”
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CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction by Venkatesan, Balachandar, Valente, Anthony J., Das, Nitin A., Carpenter, Andrea J., Yoshida, Tadashi, Delafontaine, Jean-Luc, Siebenlist, Ulrich, Chandrasekar, Bysani

“…Hyperglycemia-induced endothelial dysfunction is characterized by enhanced inflammatory cytokine and adhesion molecule expression, and endothelial–monocyte…”
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Effect of inhaled tacrolimus on ischemia reperfusion injury in rat lung transplant model by Bayer, Johanna, MD, Das, Nitin A., MD, Baisden, Clinton E., MD, Rani, Meenakshi, PhD, DeArmond, Daniel T., MD, Peters, Jay I., MD, Johnson, Scott B., MD

“…Objective Systemic tacrolimus therapy has been shown to protect against lung ischemia-reperfusion injury in animal models. We sought to investigate on a…”
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Chest Tubes as a Platform for Physiologic Monitoring by DeArmond, Daniel T., Das, Nitin A.

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Selective versus nonselective arterial clamping during laparoscopic partial nephrectomy: impact upon renal function in the setting of a solitary kidney in a porcine model by Benway, Brian M, Baca, Geneva, Bhayani, Sam B, Das, Nitin A, Katz, Matthew D, Diaz, Dilmer L, Maxwell, Keegan L, Badwan, Khalid H, Talcott, Michael R, Liapis, Helen, Cabello, Jose M, Venkatesh, Ramakrishna, Figenshau, Robert S

“…Laparoscopic partial nephrectomy has emerged as a standard of care for small renal masses. Nevertheless, there remains concern over the potential for…”
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Metformin inhibits aldosterone-induced cardiac fibroblast activation, migration and proliferation in vitro, and reverses aldosterone + salt-induced cardiac fibrosis in vivo by Mummidi, Srinivas, Das, Nitin A, Carpenter, Andrea J, Kandikattu, Hemanthkumar, Krenz, Maike, Siebenlist, Ulrich, Valente, Anthony J, Chandrasekar, Bysani

“…Abstract The overall goals of this study were to investigate whether metformin exerts anti-fibrotic effects in Aldosterone + salt-treated wild type mouse…”
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Diagnosis of anastomotic leak: Electrolyte detection versus barium fluoroscopy by DeArmond, Daniel T., MD, Carswell, Aimee, MD, Louden, Christopher L., MS, Simmons, Jeremy D., MD, Bayer, Johanna, MD, Das, Nitin A., MD, Johnson, Scott B., MD, FACS, FCCP

“…Abstract Background We recently described a new method of diagnosing anastomotic leak using the detection of electrical changes induced by electrolyte…”
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Minocycline reverses IL-17A/TRAF3IP2-mediated p38 MAPK/NF-κB/iNOS/NO-dependent cardiomyocyte contractile depression and death by Yoshida, Tadashi, Das, Nitin A., Carpenter, Andrea J., Izadpanah, Reza, Kumar, Senthil A., Gautam, Sandeep, Bender, Shawn B., Siebenlist, Ulrich, Chandrasekar, Bysani

“…Minocycline, an FDA-approved second-generation semisynthetic tetracycline, exerts antioxidant, anti-apoptotic and anti-inflammatory effects, independent of its…”
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Apyrase treatment prevents ischemia–reperfusion injury in rat lung isografts by Sugimoto, Seiichiro, MD, PhD, Lin, Xue, MD, Lai, Jiaming, MD, Okazaki, Mikio, MD, PhD, Das, Nitin A., MD, Li, Wenjun, MD, Krupnick, Alexander S., MD, Chen, Ridong, PhD, Jeong, Soon Seog, PhD, Patterson, G.A., MD, Kreisel, Daniel, MD, PhD, Gelman, Andrew E., PhD

“…Objective Endothelial cells express the ectoenzyme ectonucleoside adenosine triphosphate diphosphohydrolase, an apyrase that inhibits vascular inflammation by…”
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TRAF3IP2 mediates high glucose-induced endothelin-1 production as well as endothelin-1-induced inflammation in endothelial cells by Padilla, Jaume, Carpenter, Andrea J, Das, Nitin A, Kandikattu, Hemanth Kumar, López-Ongil, Susana, Martinez-Lemus, Luis A, Siebenlist, Ulrich, DeMarco, Vincent G, Chandrasekar, Bysani

“…Hyperglycemia-induced production of endothelin (ET)-1 is a hallmark of endothelial dysfunction in diabetes. Although the detrimental vascular effects of…”
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Two Decades of Declining Medicare Reimbursement in Cardiac Surgery by Treffalls, John A., Shah, Aakash M., Worrell, Christopher M., Treffalls, Rebecca N., Das, Nitin A., Hui, Dawn S., Calhoon, John H.

“…Given the uncertainty of US health care finances, an understanding of reimbursement trends has become increasingly important in the field of cardiac surgery…”
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Lung transplant patients with coronary artery disease rarely die of cardiac causes by Makey, Ian A., Sui, Jin W., Huynh, Charles, Das, Nitin A., Thomas, Mathew, Johnson, Scott

“…Background A relative contraindication for lung transplant (LT) is coronary disease burden sufficient to cause risk of myocardial infarction after LT. We…”
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Toward a Next-Generation Digital Chest Tube by DeArmond, Daniel T., Holt, Lucas M., Wang, Andrew P., Errico, Kristen N., Das, Nitin A.

“…Chest tubes in patients who have undergone pulmonary resection with pleural air leak are painful, impair ventilatory mechanics, and increase hospital length of…”
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Agitation Techniques to Enhance Drainage of Retained Hemothorax by Makey, Ian A., Das, Nitin A., Jacob, Samuel, El-Sayed Ahmed, Magdy M., Makey, Colleen M., Johnson, Scott B., Thomas, Mathew

“…Background. Retained hemothorax (RH) is a common problem in cardiothoracic and trauma surgery. We aimed to determine the optimum agitation technique to enhance…”
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Pleural electrical impedance is a sensitive, real-time indicator of pneumothorax by DeArmond, Daniel T., Das, Nitin A., Restrepo, Carlos S., Johnson, Scott B., Michalek, Joel E., Hernandez, Brian S.

“…Chest tube management protocols, particularly in patients with alveolar-pleural air leak due to recent surgery or trauma, are limited by concerns over safety,…”
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