Search Results - "Das, Kumitaa Theva"

Genome-wide identification of Aedes albopictus long noncoding RNAs and their association with dengue and Zika virus infection by Azlan, Azali, Obeidat, Sattam M, Theva Das, Kumitaa, Yunus, Muhammad Amir, Azzam, Ghows

“…The Asian tiger mosquito, Aedes albopictus (Ae. albopictus), is an important vector that transmits arboviruses such as dengue (DENV), Zika (ZIKV) and…”
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The Effects of Lentivirus-Mediated Gene Silencing of RARβ on the Stemness Capability of Non-Small Cell Lung Cancer by Abu Halim, Noor Hanis, Zakaria, Norashikin, Theva Das, Kumitaa, Lin, Juntang, Lim, Moon Nian, Fakiruddin, Kamal Shaik, Yahaya, Badrul Hisham

“…Retinoic acid receptor beta is a nuclear receptor protein that binds to retinoic acid (RA) to mediate cellular signalling in embryogenic morphogenesis, cell…”
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Lessons Learned From Failures and Success Stories of HIV Breakthroughs: Are We Getting Closer to an HIV Cure? by Kalidasan, V, Theva Das, Kumitaa

“…There is a continuous search for an HIV cure as the success of ART in blocking HIV replication and the role of CD4 T cells in HIV pathogenesis and immunity do…”
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A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system by Kalidasan, V., Ng, Wai Hoe, Ishola, Oluwaseun Ayodeji, Ravichantar, Nithya, Tan, Jun Jie, Das, Kumitaa Theva

“…Gene therapy revolves around modifying genetic makeup by inserting foreign nucleic acids into targeted cells via gene delivery methods to treat a particular…”
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CRISPR/Cas9 technology: A promising gene-editing tool for the treatment of cancers by Ahmad, Muhammad Khairi, Theva Das, Kumitaa, Abdul Razak, Siti Razila

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OTUB1 expression and interaction network analyses in MCF-7 breast cancer cells by Iskandar, Athirah, Zulkifli, Nur Wahida, Ahmad, Muhammad Khairi, Theva Das, Kumitaa, Zulkifle, Nurulisa

“…OTUB1 is a deubiquitin enzyme that plays important role in cancer-related events. Prompted by the lack of information about OTUB1's potential as a breast…”
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Is Malaysia Ready for Human Gene Editing: A Regulatory, Biosafety and Biosecurity Perspective by Kalidasan, V, Theva Das, Kumitaa

“…Gene editing platforms have revolutionized the field of genetics with a direct impact on the public health system. Although there are apparent benefits, it is…”
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Investigating D-Amino Acid Oxidase Expression and Interaction Network Analyses in Pathways Associated With Cellular Stress: Implications in the Biology of Aging by Kalidasan, V, Suresh, Darshinie, Zulkifle, Nurulisa, Hwei, Yap Siew, Kok Hoong, Leong, Rajasuriar, Reena, Theva Das, Kumitaa

“…D-amino acid oxidase (DAO) is a flavoenzyme that metabolizes D-amino acids by oxidative deamination, producing hydrogen peroxide (H O ) as a by-product. The…”
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Highly active zinc-finger nucleases by extended modular assembly by Bhakta, Mital S, Henry, Isabelle M, Ousterout, David G, Das, Kumitaa Theva, Lockwood, Sarah H, Meckler, Joshua F, Wallen, Mark C, Zykovich, Artem, Yu, Yawei, Leo, Heather, Xu, Lifeng, Gersbach, Charles A, Segal, David J

“…Zinc-finger nucleases (ZFNs) are important tools for genome engineering. Despite intense interest by many academic groups, the lack of robust noncommercial…”
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Latent HIV-1 provirus in vitro suppression using combinatorial CRISPR/Cas9 strategy by Kalidasan, V., Ravichantar, Nithya, Muhd Besari, Alwi, Yunus, Muhammad Amir, Mohd Yusoff, Narazah, Mohamed, Zeehaida, Theva Das, Kumitaa

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Suppression of MiR130a-3p Using CRISPR/Cas9 Induces Proliferation and Migration of Non-Small Cell Lung Cancer Cell Line by Abdollah, Nur Ainina, Mohamad Safiai, Nabil Izzatie, Ahmad, Muhammad Khairi, Das, Kumitaa Theva, Abdul Razak, Siti Razila

“…BACKGROUND: Molecular alterations of microRNA130a (miR130a) are observed in many types of cancers, including non-small cell lung cancer (NSCLC). However, the…”
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HLA-B57:01 Typing in a Malaysian Cohort: Implications of Abacavir Hypersensitivity in People Living with HIV by Kalidasan, V, Kunalan, Iswarya, Rajasuriar, Reena, Subbiah, Vijay Kumar, Das, Kumitaa Theva

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Playing God? Religious Perspectives on Manipulating the Genome by Kalidasan, V., Das, Kumitaa Theva

“…The Human Genome Project (HGP) is a remarkable medical science breakthrough that enables the understanding of genetics and the intervention of human health. An…”
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d-Amino acids differentially trigger an inflammatory environment in vitro by Yap, Siew Hwei, Lee, Cheng Siang, Zulkifli, Nur Diyana, Suresh, Darshinie, Hamase, Kenji, Das, Kumitaa Theva, Rajasuriar, Reena, Leong, Kok Hoong

“…Studies in vivo have demonstrated that the accumulation of d -amino acids ( d -AAs) is associated with age-related diseases and increased immune activation…”
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Using zinc finger nucleases (zfn) to permanently inactivate hiv by Theva Das, Kumitaa

“…More than 25 million people have died due to AIDS. Although it has been more than 20 years since HIV was first discovered, a cure for AIDS has yet to be found…”
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Dissecting the genetic architecture of coronary artery disease by genome engineering by Segal, David J, Bhakta, Mital S, Das, Kumitaa Theva, Sun, Chongxiu, Grace, Natalie M, Nolta, Jan A, Knowlton, Anne A, Rocke, David M, Simon, Scott I

“…Doc number: P34…”
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