Search Results - "Das, Joyjyoti"
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Fluid shear stress influences invasiveness of HeLa cells through the induction of autophagy
Published in Clinical & experimental metastasis (01-06-2022)“…Extravasation of metastatic cells from the blood or lymphatic circulation and formation of secondary tumor at a distant site is a key step of cancer…”
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2
One- and Two-Photon-Activated Cysteine Persulfide Donors for Biological Targeting
Published in Journal of organic chemistry (20-09-2019)“…Persulfides have been considered as potential signaling compounds similar to the H2S in “S-persulfidation”, a sulfur-mediated redox cycle. The research of this…”
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Hemodynamic shear stress induces protective autophagy in HeLa cells through lipid raft-mediated mechanotransduction
Published in Clinical & experimental metastasis (01-03-2018)“…During metastatic dissemination, cancer cells experience shear stresses in narrow confinements of in vivo vasculature. Such stresses are currently known to…”
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Development of gelatin/carboxymethyl chitosan/nano-hydroxyapatite composite 3D macroporous scaffold for bone tissue engineering applications
Published in Carbohydrate polymers (01-06-2018)“…[Display omitted] •3D macroporous scaffold was developed by high speed stirring and freeze drying method.•SGC and NGC scaffolds had significantly different…”
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Mechanical stress-induced autophagic response: A cancer-enabling characteristic?
Published in Seminars in cancer biology (01-11-2020)“…Metastasis is the leading cause of cancer mortality. Throughout the cascade of metastasis, cancer cells are exposed to both chemical and mechanical cues which…”
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PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applications
Published in Colloids and surfaces, B, Biointerfaces (01-12-2018)“…[Display omitted] •Paper matrix was functionalized with PAMAM dendrimers using glutaraldehyde.•PF matrix supported higher protein adsorption and dye…”
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Evolution of lipid nanoparticles as charioteers of Alzheimer's disease therapeutics
Published in Applied materials today (01-12-2024)“…•Alzheimer's disease (AD) represents a significant global health challenge and is among the most intricate neurodegenerative diseases.•Lipid nanoparticles…”
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Compressive stress-induced autophagy promotes invasion of HeLa cells by facilitating protein turnover in vitro
Published in Experimental cell research (15-08-2019)“…Metastasis remains the primary cause of cancer mortality. Throughout the process of metastasis, cancer cells experience mechanical forces, which may turn out…”
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Abstract A021: Bone marrow mesenchymal stem cells tune autophagic circuitry of chronic myeloid leukemia cells in response to imatinib treatment
Published in Molecular cancer therapeutics (01-01-2018)“…Chronic myeloid leukemia (CML) is a stem cell disorder with the characteristic presence of chromosomal translocation resulting in the formation of Bcr-Abl…”
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Role of PI3K/Akt/mTOR and MEK/ERK pathway in Concanavalin A induced autophagy in HeLa cells
Published in Chemico-biological interactions (05-03-2014)“…•Con A induces robust autophagy in HeLa dose and time dependently.•Con A induces fraction of HeLa cell death through autophagy induced apoptosis.•Con A…”
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Role of Escherichia coli endopeptidases and dd-carboxypeptidases in infection and regulation of innate immune response
Published in Microbes and infection (01-12-2019)“…The low-molecular-mass penicillin-binding proteins, involved in peptidoglycan recycling can also produce peptidoglycan fragments capable of activating an…”
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Environment Activatable Nanoprodrug: Two-Step Surveillance in the Anticancer Drug Release
Published in ACS applied materials & interfaces (30-08-2017)“…Remedial cancer therapy deals with a large number of theranostic applications. However, systems, so far known, are only capable of single surveillance for both…”
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Cell penetrating peptides from agglutinin protein of Abrus precatorius facilitate the uptake of Imatinib mesylate
Published in Colloids and surfaces, B, Biointerfaces (01-04-2016)“…[Display omitted] •Two peptides SR11 and IR15 were obtained from tryptic digest of Abrus agglutinin.•SR11 and IR15 are nontoxic and both have cell penetrating…”
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Abrus Agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy‐dependent cell death
Published in Molecular carcinogenesis (01-02-2017)“…Abrus agglutinin (AGG), a type II ribosome‐inactivating protein has been found to induce mitochondrial apoptosis. In the present study, we documented that…”
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Single component image guided ‘On-demand’ drug delivery system for early stage prostate cancer
Published in Sensors and actuators. B, Chemical (01-06-2017)“…[Display omitted] •Single component system for the early stage detection, diagnosis and treatment of prostate cancer.•Dipicolylamine-coumarin-chlorambucil…”
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Squaric Acid-Coumarin-Chlorambucil: Photoresponsive Single-Component Fluorescent Organic Nanoconjugates for Self-Monitored Therapeutics
Published in ACS applied nano materials (26-11-2018)“…In this paper, we have developed photoresponsive fluorescent organic nanoconjugates based on a single-component system for effective cancer treatment by a…”
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Molecular Mechanisms Associated With Particulate and Soluble Heteroglycan Mediated Immune Response
Published in Journal of cellular biochemistry (01-07-2016)“…ABSTRACT Immune responses are outcomes of complex molecular machinery which occur inside the cells. Unravelling the cellular mechanisms induced by immune…”
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Abrus precatorius agglutinin-derived peptides induce ROS-dependent mitochondrial apoptosis through JNK and Akt/P38/P53 pathways in HeLa cells
Published in Chemico-biological interactions (05-10-2014)“…•Cellular internalization and binding of 10kDAGP with mitochondria starts from 90min.•10kDAGP deregulates MMP and upregulates ROS from 6 to 8h…”
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