Search Results - "Das, Chandrima"

CBP/p300-mediated acetylation of histone H3 on lysine 56 by Tyler, Jessica K, Das, Chandrima, Lucia, M. Scott, Hansen, Kirk C

“…Acetylation within the globular core domain of histone H3 on lysine 56 (H3K56) has recently been shown to have a critical role in packaging DNA into chromatin…”
Get full text

Alternative splicing modulates cancer aggressiveness: role in EMT/metastasis and chemoresistance by Roy Burman, Debanwita, Das, Shalini, Das, Chandrima, Bhattacharya, Rahul

“…Enhanced metastasis and disease recurrence accounts for the high mortality rates associated with cancer. The process of Epithelial-Mesenchymal Transition (EMT)…”
Get full text

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor by Adhikary, Santanu, Chakravarti, Deepavali, Terranova, Christopher, Sengupta, Isha, Maitituoheti, Mayinuer, Dasgupta, Anirban, Srivastava, Dushyant Kumar, Ma, Junsheng, Raman, Ayush T., Tarco, Emily, Sahin, Aysegul A., Bassett, Roland, Yang, Fei, Tapia, Coya, Roy, Siddhartha, Rai, Kunal, Das, Chandrima

“…The roles of Plant Homeodomain (PHD) fingers in catalysis of histone modifications are unknown. We demonstrated that the PHD finger of Ubiquitin Protein Ligase…”
Get full text

Histone exchange and histone modifications during transcription and aging by Das, Chandrima, Tyler, Jessica K.

“…The organization of the eukaryotic genome into chromatin enables DNA to fit inside the nucleus while also regulating the access of proteins to the DNA to…”
Get full text

Phosphorylation-dependent association of human chromatin protein PC4 to linker histone H1 regulates genome organization and transcription by Mustafi, Pallabi, Hu, Mingli, Kumari, Sujata, Das, Chandrima, Li, Guohong, Kundu, Tapas K

“…Human Positive Coactivator 4 (PC4) is a multifaceted chromatin protein involved in diverse cellular processes including genome organization, transcription…”
Get full text

Selective Recognition of H3.1K36 Dimethylation/H4K16 Acetylation Facilitates the Regulation of All-trans-retinoic Acid (ATRA)-responsive Genes by Putative Chromatin Reader ZMYND8 by Adhikary, Santanu, Sanyal, Sulagna, Basu, Moitri, Sengupta, Isha, Sen, Sabyasachi, Srivastava, Dushyant Kumar, Roy, Siddhartha, Das, Chandrima

“…ZMYND8 (zinc finger MYND (Myeloid, Nervy and DEAF-1)-type containing 8), a newly identified component of the transcriptional coregulator network, was found to…”
Get full text

Host transcription factor Speckled 110 kDa (Sp110), a nuclear body protein, is hijacked by hepatitis B virus protein X for viral persistence by Sengupta, Isha, Das, Dipanwita, Singh, Shivaram Prasad, Chakravarty, Runu, Das, Chandrima

“…Promyelocytic leukemia nuclear bodies (PML-NB) are sub-nuclear organelles that are the hub of numerous proteins. DNA/RNA viruses often hijack the cellular…”
Get full text

The histone shuffle: histone chaperones in an energetic dance by Das, Chandrima, Tyler, Jessica K., Churchill, Mair E.A.

“…Our genetic information is tightly packaged into a rather ingenious nucleoprotein complex called chromatin in a manner that enables it to be rapidly accessed…”
Get full text

Suppression of poised oncogenes by ZMYND8 promotes chemo-sensitization by Mukherjee, Shravanti, Adhikary, Santanu, Gadad, Shrikanth S., Mondal, Payel, Sen, Sabyasachi, Choudhari, Ramesh, Singh, Vipin, Adhikari, Swagata, Mandal, Pratiti, Chaudhuri, Soumi, Sengupta, Amrita, Lakshmanaswamy, Rajkumar, Chakrabarti, Partha, Roy, Siddhartha, Das, Chandrima

“…The major challenge in chemotherapy lies in the gain of therapeutic resistance properties of cancer cells. The relatively small fraction of chemo-resistant…”
Get full text

UBR7 in concert with EZH2 inhibits the TGF-β signaling leading to extracellular matrix remodeling by Adhikari, Swagata, Singh, Vipin, Nandi, Sandhik, Ghosal, Manorama, Raj, Nidharshan Sundar, Khanna, Jayati, Bhattacharya, Apoorva, Kabiraj, Aindrila, Mondal, Atanu, Vasudevan, Madavan, Senapati, Dulal, Roy, Himansu, Sengupta, Kundan, Notani, Dimple, Das, Chandrima

“…The intricate interplay between resident cells and the extracellular matrix (ECM) profoundly influences cancer progression. In triple-negative breast cancer…”
Get full text

Synthesis, Characterization, X‑ray Crystal Structure, DFT Calculations, and Catalytic Properties of a Dioxidovanadium(V) Complex Derived from Oxamohydrazide and Pyridoxal: A Model Complex of Vanadate-Dependent Bromoperoxidase by Das, Chandrima, Adak, Piyali, Mondal, Satyajit, Sekiya, Ryo, Kuroda, Reiko, Gorelsky, Serge I, Chattopadhyay, Shyamal Kumar

“…A vanadium(V) complex with the formula [Et3NH][VVO2(sox-pydx)] with a new tridentate ligand…”
Get full text

Co-Loading of Black Phosphorus Nanoflakes and Doxorubicin in Lysolipid Temperature-Sensitive Liposomes for Combination Therapy in Prostate Cancer by Das, Chandrima, Martín, Cristina, Habermann, Sebastian, Walker, Harriet Rose, Iqbal, Javed, Elies, Jacobo, Jones, Huw Simon, Reina, Giacomo, Ruiz, Amalia

“…Black phosphorus (BP) is one of the most promising nanomaterials for cancer therapy. This 2D material is biocompatible and has strong photocatalytic activity,…”
Get full text

Emerging Roles of Estrogen-Regulated Enhancer and Long Non-Coding RNAs by Sedano, Melina J, Harrison, Alana L, Zilaie, Mina, Das, Chandrima, Choudhari, Ramesh, Ramos, Enrique, Gadad, Shrikanth S

“…Genome-wide RNA sequencing has shown that only a small fraction of the human genome is transcribed into protein-coding mRNAs. While once thought to be "junk"…”
Get full text

Natural Flavonoids in the Prevention and Treatment of Lung Cancer: A Pharmacological Aspect by Nath, Rajat, Das, Chandrima, Kityania, Sibashish, Nath, Deepa, Das, Subrata, Choudhury, Manabendra Dutta, Patra, Jayanta Kumar, Talukdar, Anupam Das

“…Deadly disease cancer has many types; among them, lung cancer is responsible for the highest number of cancer mortality. Existing therapies as well as drugs…”
Get more information

ZMYND8 suppresses MAPT213 LncRNA transcription to promote neuronal differentiation by Adhikary, Santanu, Singh, Vipin, Choudhari, Ramesh, Yang, Barbara, Adhikari, Swagata, Ramos, Enrique I., Chaudhuri, Soumi, Roy, Siddhartha, Gadad, Shrikanth S., Das, Chandrima

“…Zinc Finger transcription factors are crucial in modulating various cellular processes, including differentiation. Chromatin reader Zinc Finger MYND (Myeloid,…”
Get full text

Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study by Das, Dipanwita, Sarkar, Neelakshi, Sengupta, Isha, Pal, Ananya, Saha, Debraj, Bandopadhyay, Manikankana, Das, Chandrima, Narayan, Jimmy, Singh, Shivram Prasad, Chakravarty, Runu

“…AIM Toll like receptors plays a significant anti-viral role in different infections. The aim of this study was to look into the role of toll like receptor…”
Get full text

Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation by Das, Chandrima, Roy, Siddhartha, Namjoshi, Sarita, Malarkey, Christopher S., Jones, David N. M., Kutateladze, Tatiana G., Churchill, Mair E. A., Tyler, Jessica K.

“…The multifunctional Creb-binding protein (CBP) protein plays a pivotal role in many critical cellular processes. Here we demonstrate that the bromodomain of…”
Get full text

The DNA intercalators ethidium bromide and propidium iodide also bind to core histones by Banerjee, Amrita, Majumder, Parijat, Sanyal, Sulagna, Singh, Jasdeep, Jana, Kuladip, Das, Chandrima, Dasgupta, Dipak

“…•DNA intercalators ethidium bromide and propidium iodide also bind to core histones.•These ligands release DNA from the chromatosome.•These ligands cause…”
Get full text

A novel role of tumor suppressor ZMYND8 in inducing differentiation of breast cancer cells through its dual-histone binding function by Mukherjee, Shravanti, Sen, Sabyasachi, Adhikary, Santanu, Sengupta, Amrita, Mandal, Pratiti, Dasgupta, Dipak, Chakrabarti, Partha, Roy, Siddhartha, Das, Chandrima

“…Accumulating evidences indicate the involvement of epigenetic deregulations in cancer. While some epigenetic regulators with aberrant functions in cancer are…”
Get full text

Phytochemical composition analysis and evaluation of in vitro medicinal properties and cytotoxicity of five wild weeds: A comparative study [version 1; peer review: 1 approved, 2 approved with reservations] by Ghosh, Pranabesh, Das, Chandrima, Biswas, Swagata, Nag, Sudip Kumar, Dutta, Alolika, Biswas, Maitrayee, Sil, Sayantan, Hazra, Labani, Ghosh, Chandreyi, Das, Shaktijit, Saha, Moumita, Mondal, Nasim, Mandal, Suprodip, Ghosh, Anirban, Karmakar, Srabani, CHATTERJEE, SIRSHENDU

“…Background: Medicinal plants are a source of phytochemicals and they are used for the treatment of several oxidative stress-related or other diseases for their…”
Get full text