Search Results - "Das, Anusuya"

The promotion of mandibular defect healing by the targeting of S1P receptors and the recruitment of alternatively activated macrophages by Das, Anusuya, Segar, Claire E, Hughley, Brian B, Bowers, Daniel T, Botchwey, Edward A

“…Abstract Endogenous signals originating at the site of injury are involved in the paracrine recruitment, proliferation, and differentiation of circulating…”
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Current concepts of bone tissue engineering for craniofacial bone defect repair by Fishero, Brian Alan, Kohli, Nikita, Das, Anusuya, Christophel, John Jared, Cui, Quanjun

“…Craniofacial fractures and bony defects are common causes of morbidity and contribute to increasing health care costs. Successful regeneration of bone requires…”
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Delivery of bioactive lipids from composite microgel-microsphere injectable scaffolds enhances stem cell recruitment and skeletal repair by Das, Anusuya, Barker, Daniel A, Wang, Tiffany, Lau, Cheryl M, Lin, Yong, Botchwey, Edward A

“…In this study, a microgel composed of chitosan and inorganic phosphates was used to deliver poly(lactic-co-glycolic acid) (PLAGA) microspheres loaded with…”
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Bioactive lipid coating of bone allografts directs engraftment and fate determination of bone marrow-derived cells in rat GFP chimeras by Das, Anusuya, Segar, Claire E, Chu, Yihsuan, Wang, Tiffany W, Lin, Yong, Yang, Chunxi, Du, Xeujun, Ogle, Roy C, Cui, Quanjun, Botchwey, Edward A

“…Abstract Bone grafting procedures are performed to treat wounds incurred during wartime trauma, accidents, and tumor resections. Endogenous mechanisms of…”
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Abluminal stimulation of sphingosine 1-phosphate receptors 1 and 3 promotes and stabilizes endothelial sprout formation by Das, Anusuya, Lenz, Steven M, Awojoodu, Anthony O, Botchwey, Edward A

“…Local delivery of lipid mediators has become a promising new approach for therapeutic angiogenesis and regenerative medicine. In this study, we investigated…”
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Patentability Challenges in Personalized Medicine: A Fork in the Road by Das, Anusuya

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Evaluation of angiogenesis and osteogenesis by Das, Anusuya, Botchwey, Edward

“…Bone regeneration has long been a major focus for tissue engineers and the importance of vascularization to the bone regeneration process has been well…”
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Osteonecrosis of the femoral head: An update in year 2012 by Kaushik, Anjan P, Das, Anusuya, Cui, Quanjun

“…Osteonecrosis is a phenomenon involving disruption to the vascular supply to the femoral head, resulting in articular surface collapse and eventual…”
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Sphingosine‐1‐Phosphate Receptor‐3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche by Ogle, Molly E., Olingy, Claire E., Awojoodu, Anthony O., Das, Anusuya, Ortiz, Rafael A., Cheung, Hoi Yin, Botchwey, Edward A.

“…Hematopoietic stem and progenitor cells (HSPCs) egress from bone marrow (BM) during homeostasis and at increased rates during stress; however, the mechanisms…”
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Delivery of S1P receptor-targeted drugs via biodegradable polymer scaffolds enhances bone regeneration in a critical size cranial defect by Das, Anusuya, Tanner, Shaun, Barker, Daniel A., Green, David, Botchwey, Edward A.

“…Biodegradable polymer scaffolds can be used to deliver soluble factors to enhance osseous remodeling in bone defects. To this end, we designed a…”
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Local delivery of FTY720 accelerates cranial allograft incorporation and bone formation by Huang, Cynthia, Das, Anusuya, Barker, Daniel, Tholpady, Sunil, Wang, Tiffany, Cui, Quanjun, Ogle, Roy, Botchwey, Edward

“…Endogenous stem cell recruitment to the site of skeletal injury is key to enhanced osseous remodeling and neovascularization. To this end, this study utilized…”
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A hybrid continuum-discrete modelling approach to predict and control angiogenesis: analysis of combinatorial growth factor and matrix effects on vessel-sprouting morphology by Das, Anusuya, Lauffenburger, Douglas, Asada, Harry, Kamm, Roger D.

“…Angiogenesis is crucial during many physiological processes and is influenced by various biochemical and biomechanical factors. Models have proved useful in…”
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Poly(lactic-co-glycolide) polymer constructs cross-linked with human BMP-6 and VEGF protein significantly enhance rat mandible defect repair by Das, Anusuya, Fishero, Brian A., Christophel, J. Jared, Li, Ching-Ju, Kohli, Nikita, Lin, Yong, Dighe, Abhijit S., Cui, Quanjun

“…We have previously shown that the combined delivery of mesenchymal stem cells (MSCs), vascular endothelial growth factor (VEGF) and bone morphogenetic protein…”
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Spatiotemporal Oxygen Sensing Using Dual Emissive Boron Dye–Polylactide Nanofibers by Bowers, Daniel T, Tanes, Michael L, Das, Anusuya, Lin, Yong, Keane, Nicole A, Neal, Rebekah A, Ogle, Molly E, Brayman, Kenneth L, Fraser, Cassandra L, Botchwey, Edward A

“…Oxygenation in tissue scaffolds continues to be a limiting factor in regenerative medicine despite efforts to induce neovascularization or to use…”
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Deferoxamine Mitigates Radiation-Induced Tissue Injury in a Rat Irradiated TRAM Flap Model by Mericli, Alexander F., Das, Anusuya, Best, Ryan, Rodeheaver, Pamela, Rodeheaver, George, Lin, Kant Y.

“…Radiation therapy results in permanent damage to the microvasculature, leading to dermal damage and inelasticity in normal tissues. Deferoxamine is a U.S. Food…”
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Poly by Fishero, Brian A, Dighe, Abhijit S, Kohli, Nikita, Christophel, J. Jared, Lin, Yong, Cui, Quanjun, Das, Anusuya, Li, Ching-Ju

“…We have previously shown that the combined delivery of mesenchymal stem cells (MSCs), vascular endothelial growth factor (VEGF) and bone morphogenetic protein…”
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Abstract 107: Deferoxamine Mitigates Radiation-Induced Hypovascularity and Improves Tissue Elasticity in a Rat Irradiated TRAM Flap Model by Mericli, Alexander F, Das, Anusuya, Best, Ryan, Rodeheaver, Pamela, Rodeheaver, George, Lin, Kant Y

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Abstract 110: The Impact of Deferoxamine on Vascularity and Soft Tissue Biomechanics in a Rat TRAM Flap Model by Mericli, Alexander F, Das, Anusuya, Rodeheaver, Pamela, Rodeheaver, George, Lin, Kant Y

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The Impact of Deferoxamine on Vascularity and Soft-Tissue Biomechanics in a Rat TRAM Flap Model by Mericli, Alexander F., Das, Anusuya, Rodeheaver, Pamela, Rodeheaver, George T., Lin, Kant Y.

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Enhanced osseous integration of human trabecular allografts following surface modification with bioactive lipids by Wang, Tiffany, Krieger, Jack, Huang, Cynthia, Das, Anusuya, Francis, Michael P., Ogle, Roy, Botchwey, Edward

“…In this study, we used extracellular matrix (ECM) gels and human bone allograft as matrix vehicles to deliver the sphingolipid growth factor FTY720 to rodent…”
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