Search Results - "Darweesh, Mahmoud"

Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections by Hajikhezri, Zamaneh, Darweesh, Mahmoud, Akusjärvi, Göran, Punga, Tanel

“…The zinc finger proteins make up a significant part of the proteome and perform a huge variety of functions in the cell. The CCCH-type zinc finger proteins…”
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An innovative dual recognition aptasensor for specific detection of Staphylococcus aureus based on Au/Fe3O4 binary hybrid by El-Wekil, Mohamed M., Halby, Hamada Mohamed, Darweesh, Mahmoud, Ali, Mohamed E., Ali, Ramadan

“…Pathogenic bacteria cause disease outbreaks and threaten human health, prompting the research on advanced detection assays. Herein, we developed a selective…”
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Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs by Punga, Tanel, Darweesh, Mahmoud, Akusjärvi, Göran

“…Human adenoviruses (HAdVs) are common pathogens causing a variety of respiratory, ocular and gastrointestinal diseases. To accomplish their efficient…”
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Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation by Darweesh, Mahmoud, Kamel, Wael, Gavrilin, Mikhail A, Akusjärvi, Göran, Svensson, Catharina

“…Virus infected immune cells can rapidly respond to the invader by activating the inflammasome and as a consequence release proinflammatory cytokines and…”
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Both cytopathic and non-cytopathic bovine viral diarrhea virus (BVDV) induced autophagy at a similar rate by Rajput, Mrigendra K.S., Abdelsalam, Karim, Darweesh, Mahmoud F., Braun, Lyle J, Kerkvliet, Jason, Hoppe, Adam D., Chase, Christopher C.L.

“…•Both cytopathic and non-cytopathic BVDV induce autophagy in immortal as well as primary cells.•Immortal cells had higher autophagy as compare to primary…”
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ZFP36 ring finger protein like 1 significantly suppresses human coronavirus OC43 replication by Momin, Tooba, Villasenor, Andrew, Singh, Amit, Darweesh, Mahmoud, Singh, Aditi, Rajput, Mrigendra

“…CCCH-type zinc figure proteins (ZFP) are small cellular proteins that are structurally maintained by zinc ions. Zinc ions coordinate the protein structure in a…”
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BVDV Npro protein mediates the BVDV induced immunosuppression through interaction with cellular S100A9 protein by Darweesh, Mahmoud F., Rajput, Mrigendra K.S., Braun, Lyle J., Rohila, Jai S., Chase, Christopher C.L.

“…The innate immune response is a vital part of the body's antiviral defense system. The innate immune response is initiated by various receptor interactions,…”
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Comparative humoral immune response against cytopathic or non-cytopathic bovine viral diarrhea virus infection by Rajput, Mrigendra K.S., Darweesh, Mahmoud F., Braun, Lyle J., Mansour, Shimaa M.G., Chase, Christopher C.L.

“…Bovine viral diarrhea virus (BVDV) infection causes immune dysfunction. The current study investigated the effect of cytopathic (cp) or noncytopathic (ncp)…”
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ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression by Darweesh, Mahmoud, Younis, Shady, Hajikhezri, Zamaneh, Ali, Arwa, Jin, Chuan, Punga, Tanel, Gupta, Soham, Essand, Magnus, Andersson, Leif, Akusjärvi, Göran

“…ZC3H11A is a cellular protein associated with the transcription export (TREX) complex that is induced during heat-shock. Several nuclear-replicating viruses…”
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The effect of bovine viral diarrhea virus (BVDV) strains on bovine monocyte-derived dendritic cells (Mo-DC) phenotype and capacity to produce BVDV by Rajput, Mrigendra K S, Darweesh, Mahmoud F, Park, Kaci, Braun, Lyle J, Mwangi, Waithaka, Young, Alan J, Chase, Christopher C L

“…Dendritic cells (DC) are important antigen presentation cells that monitor, process, and present antigen to T cells. Viruses that infect DC can have a…”
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Bovine natural killer cells are infected by BVDV and the infection results in changes in phenotype and activation markers (P6128) by Darweesh, Mahmoud Darweesh, Rajput, Mrigendra, Lebedev, Max, Young, Alan, Braun, Lyle, Chase, Christopher

“…Abstract Bovine viral diarrhea virus infection results in immunosuppression and persistence infection of fetuses. Understanding the interaction between BVDV…”
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Immune response to bovine viral diarrhea virus--looking at newly defined targets by Chase, Christopher C L, Thakur, Neelu, Darweesh, Mahmoud F, Morarie-Kane, Susan E, Rajput, Mrigendra K

“…Bovine viral diarrhea virus (BVDV) has long been associated with a wide variety of clinical syndromes and immune dysregulation, many which result in secondary…”
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Characterization of the cytopathic BVDV strains isolated from 13 mucosal disease cases arising in a cattle herd by Darweesh, Mahmoud F., Rajput, Mrigendra K.S., Braun, Lyle J., Ridpath, Julia F., Neill, John D., Chase, Christopher C.L.

“…•First characterization of multiple cytopathic BVDV isolates from a single herd.•All the viruses had a cellular DnaJ insertion in the NS2-3 junction.•The…”
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Characterization of the Cytopathic BVDV Strains Isolated From 13 Mucosal Disease Cases Arising in a Cattle Herd by Darweesh, Mahmoud

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Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism by Hajikhezri, Zamaneh, Kaira, Yanina, Schubert, Erik, Darweesh, Mahmoud, Svensson, Catharina, Akusjärvi, Göran, Punga, Tanel

“…Human adenoviruses (HAdVs) are widespread pathogens causing a variety of diseases. A well-controlled expression of virus capsid mRNAs originating from the…”
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Enzyme-free and label-free strategy for electrochemical oxaliplatin aptasensing by using rGO/MWCNTs loaded with AuPd nanoparticles as signal probes and electro-catalytic enhancers by El-Wekil, Mohamed M., Darweesh, Mahmoud, Shaykoon, Montaser Sh A., Ali, Ramadan

“…An innovative label free electrochemical aptasensor was developed for the analysis of oxaliplatin (OXAL) for the first time. The DNA oligonucleotide (aptamer)…”
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The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts by Kases, Katharina, Schubert, Erik, Hajikhezri, Zamaneh, Larsson, Mårten, Devi, Priya, Darweesh, Mahmoud, Andersson, Leif, Akusjärvi, Göran, Punga, Tanel, Younis, Shady

“…Nuclear mRNA metabolism is regulated by multiple proteins, which either directly bind to RNA or form multiprotein complexes. The RNA-binding protein ZC3H11A is…”
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Nanostructured gold-embedded porous carbon black nanoceramic film coating on pencil graphite rods: An innovative disposable ultrasensitive sensor for monitoring dopamine by Alanazi, Ahmed Z., Alhazzani, Khalid, El-Wekil, Mohamed M., Ali, Al-Montaser Bellah H., Darweesh, Mahmoud, Ibrahim, Hossieny

“…[Display omitted] •Nanostructured gold-anchored conductive porous carbon black (Au@PCB) was synthesized.•A new Au@PCB nanoceramic film coated pencil graphite…”
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Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response by Ali, Arwa, Contreras, Paola, Darweesh, Mahmoud, Andersson, Leif, Jin, Chuan, Essand, Magnus, Yu, Di

“…Zinc finger CCCH containing 11A (ZC3H11A) is a stress-induced protein that is upregulated in various conditions such as heat shock and virus infection. It has…”
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Self‐Calibrating Copper‐Based Metal Organic Frameworks for Ratiometric Electrochemical Sensing of Creatinine by Alanazi, Ahmed Z., Alhazzani, Khalid, Ali, Al‐Montaser Bellah H., Darweesh, Mahmoud, Ibrahim, Hossieny, El‐Wekil, Mohamed M

“…Abstract Nanostructures that can undergo redox reactions have significant potential for electrochemical analysis. They can act as signal amplifiers to…”
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