Search Results - "Darveau, RP"

Porphyromonas gingivalis Lipopolysaccharide Contains Multiple Lipid A Species That Functionally Interact with Both Toll-Like Receptors 2 and 4 by DARVEAU, Richard P, PHAM, Thu-Thao T, LEMLEY, Kayde, REIFE, Robert A, BAINBRIDGE, Brian W, COATS, Stephen R, HOWALD, William N, SING SING WAY, HAJJAR, Adeline M

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Lipopolysaccharide Heterogeneity: Innate Host Responses to Bacterial Modification of Lipid A Structure by Dixon, D.R., Darveau, R.P.

“…The innate host response system is composed of various mechanisms designed to detect and facilitate host responses to microbial components, such as…”
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MD-2 Mediates the Ability of Tetra-Acylated and Penta-Acylated Lipopolysaccharides to Antagonize Escherichia coli Lipopolysaccharide at the TLR4 Signaling Complex by Coats, Stephen R, Pham, Thu-Thao T, Bainbridge, Brian W, Reife, Robert A, Darveau, Richard P

“…We have demonstrated previously that tetra-acylated LPS derived from the oral bacterium, Porphyromonas gingivalis, and penta-acylated msbB LPS derived from a…”
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The Expression Profile of Lipopolysaccharide‐Binding Protein, Membrane‐Bound CD14, and Toll‐Like Receptors 2 and 4 in Chronic Periodontitis by Ren, Lei, Leung, W. Keung, Darveau, Richard P., Jin, Lijian

“…Background: This study aimed to investigate the interrelationship of in vivo expression of lipopolysaccharide‐binding protein (LBP) and membrane‐bound CD14…”
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Inducible expression of human β-defensin 2 by Fusobacterium nucleatum in oral epithelial cells : Multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier by KRISANAPRAKORNKIT, S, KIMBALL, J. R, WEINBERG, A, DARVEAU, R. P, BAINBRIDGE, B. W, DALE, B. A

“…Human gingival epithelial cells (HGE) express two antimicrobial peptides of the beta-defensin family, human beta-defensin 1 (hBD-1) and hBD-2, as well as…”
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Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity: differential activities of tetra‐ and penta‐acylated lipid A structures on E‐selectin expression and TLR4 recognition by Reife, Robert A., Coats, Stephen R., Al‐Qutub, Montaser, Dixon, Douglas M., Braham, Pamela A., Billharz, Rosalind J., Howald, William N., Darveau, Richard P.

“…Summary Porphyromonas gingivalis is a Gram‐negative bacterium strongly associated with periodontitis, a chronic inflammatory disease of the tissue surrounding…”
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Nuclear factor-[kappa]B and p38 mitogen-activated protein kinase signaling pathways are critically involved in Porphyromonas gingivalis lipopolysaccharide induction of lipopolysaccharide-binding protein expression in human oral keratinocytes by Ding, P-H, Wang, C-Y, Darveau, RP, Jin, LJ

“…Summary Lipopolysaccharide (LPS) -binding protein (LBP) plays a crucial role in innate host response to bacterial challenge. Porphyromonas gingivalis is a…”
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The microbial challenge in periodontitis by DARVEAU, RICHARD P., TANNER, ANNE, PAGE, ROY C.

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Modulation of the innate immune response within the periodontium by Dixon, Douglas R., Bainbridge, Brian W., Darveau, Richard P.

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Porphyromonas gingivalis Lipopolysaccharide Antagonizes Escherichia coli Lipopolysaccharide at Toll-Like Receptor 4 in Human Endothelial Cells by COATS, Stephen R, REIFE, Robert A, BAINBRIDGE, Brian W, PHAM, Thu-Thao T, DARVEAU, Richard P

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Regulation of Lipid A Modifications by Salmonella typhimurium Virulence Genes phoP-phoQ by Guo, Lin, Lim, Kheng B., Gunn, John S., Bainbridge, Brian, Darveau, Richard P., Hackett, Murray, Miller, Samuel I.

“…Bacterial pathogenesis requires proteins that sense host microenvironments and respond by regulating virulence gene transcription. For Salmonellae, one such…”
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Porphyromonas gingivalis lipopolysaccharide: an unusual pattern recognition receptor ligand for the innate host defense system by Bainbridge, B W, Darveau, R P

“…Lipopolysaccharide (LPS) is a key inflammatory mediator. Due to its ability to potently activate host inflammatory and innate defense responses, it has been…”
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Introduction to the Mark Wilson Conference Special Issue by Progulske-Fox, A., Fine, D.H., Darveau, R.P., Fletcher, H.M.

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Local Chemokine Paralysis, a Novel Pathogenic Mechanism for Porphyromonas gingivalis by DARVEAU, R. P, BELTON, C. M, REIFE, R. A, LAMONT, R. J

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Expression of human β-defensin-3 in gingival epithelia by Lu, Qian, Samaranayake, Lakshman P., Darveau, Richard P., Jin, Lijian

“…Objective:  This study aimed to investigate the expression patterns of the newly discovered human β‐defensin‐3 (hBD‐3) in human gingiva. Background:  Human…”
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Porphyromonas gingivalis Lipopolysaccharide Is Both Agonist and Antagonist for p38 Mitogen-Activated Protein Kinase Activation by DARVEAU, Richard P, ARBABI, Saman, GARCIA, Iris, BAINBRIDGE, Brian, MAIER, Ronald V

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Expression of human β-defensins-1 and -2 peptides in unresolved chronic periodontitis by Lu, Qian, Jin, Lijian, Darveau, Richard P., Samaranayake, Lakshman P.

“…Background:  Human β‐defensins (hBDs) are antimicrobial peptides which contribute to host innate immunity by disrupting the membrane integrity of a broad…”
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Mouse Paneth Cell Secretory Responses to Cell Surface Glycolipids of Virulent and Attenuated Pathogenic Bacteria by Tanabe, Hiroki, Ayabe, Tokiyoshi, Bainbridge, Brian, Guina, Tina, Ernst, Robert K, Darveau, Richard P, Miller, Samuel I, Ouellette, Andre J

“…Mouse Paneth cells respond to bacteria and bacterial cell surface antigens by discharging secretory granules into the lumen of small intestinal crypts (T…”
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Beneficial bacteria of the periodontium by Roberts, Frank A., Darveau, Richard P.

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A novel Escherichia coli lipid A mutant that produces an antiinflammatory lipopolysaccharide by Somerville, Jr, J E, Cassiano, L, Bainbridge, B, Cunningham, M D, Darveau, R P

“…A unique screen was used to identify mutations in Escherichia coli lipid A biosynthesis that result in a decreased ability to stimulate E-selectin expression…”
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