Search Results - "Darling, I M"

Treatment of severe, recalcitrant, chronic plaque psoriasis with fumaric acid esters: a prospective study by Wain, E.M., Darling, M.I., Pleass, R.D., Barker, J.N.W.N., Smith, C.H.

“…Summary Background  Fumaric acid esters (FAE) are used in Germany as a first‐line systemic treatment for chronic plaque psoriasis, with proven efficacy and low…”
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The south-east Scotland dermatology workload study: 30 years' analysis by Holme, S.A., Scott-Lang, V.E., Ooi, E.T., Matthews, A.G., Darling, M.I., Needham, D., McCormack, S.K.A.

“…Summary Background  Dermatological activity data have been collected for the same region of south‐east Scotland (population 1·24 million), approximately every…”
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An isolated ulcerated forehead lesion in a 70‐year‐old man by Cunningham, F., Darling, M. I., Gangopadhyay, M., Jackson, R., McKay, P., Bilsland, D.

“…Click here for the corresponding questions to this CME article…”
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Primary cutaneous amyloidosis of the glans penis. Two case reports and a review of the literature by Merika, E.E., Darling, M.Ι., Craig, P., Paul, M., Francis, N., Lachmann, H., Porter, W., Bunker, C.B.

“…Summary Background Primary cutaneous amyloidosis of the penis is a rare entity. Objectives We describe two cases of primary penile cutaneous amyloidosis…”
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Salicylate inhibits the renal transport of inorganic sulfate in rat membrane vesicle preparations by Darling, I M, Mammarella, M L, Chen, Q, Morris, M E

“…Salicylic acid (SA) administration produces a pronounced enhancement of the renal clearance of inorganic sulfate in rats. The purpose of the present…”
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Inhibitor of phospholipase A2 blocks eicosanoid and platelet activating factor biosynthesis and has topical anti-inflammatory activity by Tramposch, K M, Chilton, F H, Stanley, P L, Franson, R C, Havens, M B, Nettleton, D O, Davern, L B, Darling, I M, Bonney, R J

“…The effect of a phospholipase A2 (PLA2) inhibitor on leukotriene, prostaglandin and platelet activating factor (PAF) biosynthesis in isolated cells and in vivo…”
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Evaluation of True creatinine clearance in rats reveals extensive renal secretion by DARLING, I. M, MORRIS, M. E

“…The renal clearance of endogenous creatinine is widely used to assess glomerular filtration rate (GFR) and renal function in animal investigations. The…”
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Dermatology Symposium by Darling, MI, Sergeant, A

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Comparison of assay procedures used to measure total and unbound concentrations of quinidine by Wooding-Scott, R A, Darling, I M, Slaughter, R L

“…Individualized quinidine dosing through the assessment of serum concentrations is warranted because of the wide variability observed in its pharmacokinetic…”
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In-vivo activity of retinoid esters in skin is related to in-vitro hydrolysis rate by Chen, S, Darling, I M, Yu, K L, Starrett, Jr, J E, Mansuri, M M, Whiting, G, Tramposch, K M

“…BMS-181163 (4-acetamidophenyl retinoate, previously reported as BMY-30123), the acetamidophenyl ester of all-trans-retinoic acid (tRA), is topically active in…”
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Magnesium cerebrospinal fluid concentrations and protein binding in magnesium-deficient rats by Morris, M E, Darling, I M

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Glucocorticoid-induced alterations of renal sulfate transport by Sagawa, K, Darling, I M, Murer, H, Morris, M E

“…Glucocorticoid administration decreases renal sodium/phosphate cotransport in the proximal tubule due to a down-regulation of the sodium/phosphate…”
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Sulfate homeostasis. IV, Probenecid-induced alterations of inorganic sulfate in rats by DARLING, I. M, MORRIS, M. E

“…Homeostasis of inorganic sulfate is maintained by the capacity-limited renal reabsorption of sulfate in the proximal tubule. The purpose of the present…”
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An atypical presentation of bullous congenital ichthyosiform erythroderma by Darling, MI, Tidman, MJ

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Pharmacogenomic and pharmacokinetic assessment of liposome encapsulated SN-38 (LE-SN38) in advanced cancer patients by Kraut, E. H., Fishman, M. N., Lorusso, P. M., Steinberg, J. L., Nieves, J. A., Fetterly, G. J., Darling, I. M., Wanaski, S. P., Dul, J. L., Sherman, J. W.

“…Abstract only…”
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Pharmacogenomic and pharmacokinetic assessment of liposome encapsulated SN-38 (LE-SN38) in advanced cancer patients by Kraut, E. H., Fishman, M. N., Lorusso, P. M., Steinberg, J. L., Nieves, J. A., Fetterly, G. J., Darling, I. M., Wanaski, S. P., Dul, J. L., Sherman, J. W.

“…Abstract only…”
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Choline uptake in human intestinal Caco-2 cells is carrier-mediated by Kamath, Amrita V, Darling, Inger M, Morris, Marilyn E

“…The objective of the current investigation was to examine the transport characteristics of choline, an endogenous quaternary ammonium compound, into human…”
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