Search Results - "Darley, David"
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Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection
Published in Nature immunology (01-02-2022)“…A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer than…”
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SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants
Published in PLoS medicine (06-07-2021)“…The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody neutralization response and its evasion by emerging viral variants and variant of…”
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Multispecies Outbreak of Nocardia Infections in Heart Transplant Recipients and Association with Climate Conditions, Australia
Published in Emerging infectious diseases (01-11-2022)“…A multispecies outbreak of Nocardia occurred among heart transplant recipients (HTR), but not lung transplant recipients (LTR), in Sydney, New South Wales,…”
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Persistent symptoms up to four months after community and hospital‐managed SARS‐CoV‐2 infection
Published in Medical journal of Australia (01-04-2021)Get full text
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Psychiatric sequelae after SARS-Cov-2 infection: trajectory, predictors and associations in a longitudinal Australian cohort
Published in Acta neuropsychiatrica (01-08-2024)“…A relationship between SARS-CoV-2 infection and psychiatric symptoms has been identified but is still being fully investigated. Neuropsychiatric sequalae have…”
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Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection
Published in Nature communications (17-04-2024)“…This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID…”
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Systematic Reporting of Eosinophils in Transbronchial Biopsies After Lung Transplantation Defines a Distinct Inflammatory Response
Published in Transplantation (01-07-2024)“…Descriptions of eosinophils in transbronchial biopsy (TBBx) pathology reports after lung transplantation (LTx) are associated with poor long-term outcomes. The…”
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Specific human leucocyte antigen-DQ risk epitope mismatches are associated with chronic lung allograft dysfunction after lung transplantation
Published in American journal of transplantation (01-07-2023)“…A high-risk epitope mismatch (REM) (found in DQA1∗05 + DQB1∗02/DQB1∗03:01) is associated with de novo donor specific antibodies after lung transplantation…”
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SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern
Published in EBioMedicine (01-10-2022)“…Genetically distinct viral variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been recorded since January 2020. The introduction of…”
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Oscillometry in Stable Single and Double Lung Allograft Recipients Transplanted for Interstitial Lung Disease: Results of a Multi-Center Australian Study
Published in Transplant international (05-12-2023)“…Peak spirometry after single lung transplantation (SLTx) for interstitial lung disease (ILD) is lower than after double lung transplantation (DLTx), however…”
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Tacrolimus exposure early after lung transplantation and exploratory associations with acute cellular rejection
Published in European journal of clinical pharmacology (01-07-2019)“…Aims To (i) describe tacrolimus (TAC) pre-dose concentrations (C 0 ), (ii) calculate apparent oral TAC clearance (CL/F HCT ) adjusted for measured haematocrit…”
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The kynurenine pathway relates to post‐acute COVID‐19 objective cognitive impairment and PASC
Published in Annals of clinical and translational neurology (01-08-2023)“…Objective To determine the prevalence and natural history of post‐acute COVID‐19 objective cognitive impairment and function, and their relationship to…”
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Blood brain barrier disruption and glutamatergic excitotoxicity in post-acute sequelae of SARS COV-2 infection cognitive impairment: potential biomarkers and a window into pathogenesis
Published in Frontiers in neurology (02-05-2024)“…To investigate the association between blood-brain barrier permeability, brain metabolites, microstructural integrity of the white matter, and cognitive…”
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High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells
Published in Frontiers in immunology (05-12-2022)“…Long-term immunity to SARS-CoV-2 infection, including neutralizing antibodies and T cell-mediated immunity, is required in a very large majority of the…”
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A rare cause of intrathoracic mass
Published in Medical journal of Australia (15-02-2016)Get full text
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Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia
Published in Nature microbiology (01-06-2022)“…Genetically distinct variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged since the start of the COVID-19 pandemic. Over this…”
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A rare case of everolimus-induced pulmonary alveolar proteinosis
Published in The Journal of heart and lung transplantation (01-01-2016)Get full text
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COPD treatment choices based on blood eosinophils: are we there yet?
Published in Breathe (Lausanne, Switzerland) (01-12-2019)“…Eosinophils are increasingly being recognised as an important characteristic feature of COPD. Patients with COPD and eosinophilic inflammation tend to respond…”
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Evaluation of serological assays for SARS-CoV-2 antibody testing from dried blood spots collected from cohorts with prior SARS-CoV-2 infection
Published in Journal of clinical virology plus (01-08-2022)“…•Dried blood spots are useful sero-surveillance tools for detecting COVID-19 infection in populations hard to reach.•Validation of commercially available…”
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Chest pain and recurrent chylothorax: an unusual presentation of malignant pleural mesothelioma
Published in Respirology case reports (01-09-2017)“…Malignant mesothelioma presenting with recurrent chylous effusion is rare. We describe the case of a 34‐year‐old female Macedonian immigrant who presented with…”
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