Search Results - "Darla, Mark Manidhar"

Elucidation of the binding mechanism of coumarin derivatives with human serum albumin by Garg, Archit, Manidhar, Darla Mark, Gokara, Mahesh, Malleda, Chandramouli, Suresh Reddy, Cirandur, Subramanyam, Rajagopal

“…Coumarin is a benzopyrone which is widely used as an anti-coagulant, anti-oxidant, anti-cancer and also to cure arthritis, herpes, asthma and inflammation…”
Get full text

Binding and Molecular Dynamics Studies of 7‑Hydroxycoumarin Derivatives with Human Serum Albumin and Its Pharmacological Importance by Yeggoni, Daniel Pushparaju, Gokara, Mahesh, Mark Manidhar, Darla, Rachamallu, Aparna, Nakka, Sailaja, Reddy, Cirandur Suresh, Subramanyam, Rajagopal

“…Human serum albumin (HSA) is one of the most widely studied proteins and is an important plasma protein responsible for binding and transport of many exogenous…”
Get full text

Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease by Shaik, Jeelan Basha, Palaka, Bhagath Kumar, Penumala, Mohan, Eadlapalli, Siddhartha, Darla Mark, Manidhar, Ampasala, Dinakara Rao, Vadde, Ramakrishna, Amooru Gangaiah, Damu

“…Alzheimer's disease onset and progression are associated with the dysregulation of multiple and complex physiological processes, and a successful therapeutic…”
Get full text

Synthesis and biological evaluation of flavone-8-acrylamide derivatives as potential multi-target-directed anti Alzheimer agents and investigation of binding mechanism with acetylcholinesterase by Shaik, Jeelan Basha, Yeggoni, Daniel Pushparaju, Kandrakonda, Yelamanda Rao, Penumala, Mohan, Zinka, Raveendra Babu, Kotapati, Kasi Viswanath, Darla, Mark Manidhar, Ampasala, Dinakara Rao, Subramanyam, Rajagopal, Amooru, Damu Gangaiah

“…[Display omitted] •A series of 7-methoxyflavone and cyanoacetamides hybrids (8a–q) were synthesized.•Synthetic analogs were evaluated for their AChE, BuChE,…”
Get full text

TiO2–SiO2 Catalyzed Eco‐friendly Synthesis and Antioxidant Activity of Benzopyrano[2,3‐d]pyrimidine Derivatives by Kabeer, Shaik Ahammed, Reddy, Gajjala Raghavendra, Sreelakshmi, Poola, Manidhar, Darla Mark, Reddy, Cirandur Suresh

“…A cost‐effective and eco‐friendly synthesis of benzopyrano[2,3‐d]pyrimidine derivatives has been developed via three component one‐pot tandem approach by…”
Get full text

Investigation of binding mechanism of novel 8-substituted coumarin derivatives with human serum albumin and α-1-glycoprotein by Yeggoni, Daniel Pushpa Raju, Manidhar, Darla Mark, Suresh Reddy, Cirandur, Subramanyam, Rajagopal

“…Coumarin molecules have biological activities possessing lipid-controlling activity, anti-hepatitis C activity, anti-diabetic, anti-Parkinson activity, and…”
Get full text

TiO 2 –SiO 2 Catalyzed Eco‐friendly Synthesis and Antioxidant Activity of Benzopyrano[2,3‐ d ]pyrimidine Derivatives by Kabeer, Shaik Ahammed, Reddy, Gajjala Raghavendra, Sreelakshmi, Poola, Manidhar, Darla Mark, Reddy, Cirandur Suresh

“…A cost‐effective and eco‐friendly synthesis of benzopyrano[2,3‐ d ]pyrimidine derivatives has been developed via three component one‐pot tandem approach by…”
Get full text

Efficient Synthesis of α-Aminophosphonates and Evaluation of Significance of P˭O Group towards Antioxidant Activity by Rao, Kunda Uma Maheswara, Swapna, Sirasanagandla, Manidhar, Darla Mark, Reddy, Kandula Madhu Kumar, Reddy, Cirandur Suresh

“…A simple, efficient, and solvent-free synthesis of α-aminophosphonates has been accomplished from an amine, aromatic/ heterocyclic aldehydes, and diethyl…”
Get full text

Designing, synthesis, and characterization of some novel coumarin derivatives as probable anticancer drugs by Manidhar, Darla Mark, Kesharwani, Rajesh Kumar, Reddy, N. Bakthavatchala, Reddy, C. Suresh, Misra, Krishna

“…Coumarin is a naturally occurring oxygen heterocyclic having multifarious medicinal properties, hence used as a lead compound for designing new potent analogs…”
Get full text

Synthesis, Biological Evaluation, and Molecular Docking of 8‐imino‐2‐oxo‐2 H ,8 H ‐pyrano[2,3‐ f ]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease by Shaik, Jeelan Basha, Palaka, Bhagath Kumar, Penumala, Mohan, Eadlapalli, Siddhartha, Darla Mark, Manidhar, Ampasala, Dinakara Rao, Vadde, Ramakrishna, Amooru Gangaiah, Damu

“…Alzheimer's disease onset and progression are associated with the dysregulation of multiple and complex physiological processes, and a successful therapeutic…”
Get full text

Synthesis and bio-evaluation of novel 7-hydroxy coumarin derivatives via Knoevenagel reaction by Darla, Mark Manidhar, Krishna, Balam Sateesh, Umamaheswara Rao, K., Reddy, N. Baktavathsala, Srivash, Manoj Kumar, Adeppa, K., Sundar, Ch. Syama, Reddy, Cirandur Suresh, Misra, Krishna

“…Coumarin and 7-hydroxy coumarins have great significance as natural fragrances, having a characteristic odour like vanilla beans and their hydroxy position at…”
Get full text

Efficient Synthesis of [alpha]-Aminophosphonates and Evaluation of Significance of P=O Group towards Antioxidant Activity by Rao, Kunda Uma Maheswara, Swapna, Sirasanagandla, Manidhar, Darla Mark, Reddy, Kandula Madhu Kumar, Reddy, Cirandur Suresh

“…A simple, efficient, and solvent-free synthesis of α-aminophosphonates has been accomplished from an amine, aromatic/ heterocyclic aldehydes, and diethyl…”
Get full text