Search Results - "Darkwah, Samuel"
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Intestinal Epithelium-Derived Luminally Released Extracellular Vesicles in Sepsis Exhibit the Ability to Suppress TNF-α and IL-17A Expression in Mucosal Inflammation
Published in International journal of molecular sciences (15-09-2021)“…Sepsis is a systemic inflammatory disorder induced by a dysregulated immune response to infection resulting in dysfunction of multiple critical organs,…”
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Applying the European Union (EU) assessment initiative of forest sustainability in Africa: A case study of the timber harvesting impact on the environment in Sierra Leone
Published in Journal of forest science (Praha) (01-01-2024)“…The European Union (EU) provides both financial and expert support for sustainable forest management initiatives and also boosts compliance with such…”
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3
The Spike Glycoprotein of SARS-CoV-2 Binds to β1 Integrins Expressed on the Surface of Lung Epithelial Cells
Published in Viruses (09-04-2021)“…The spike glycoprotein attached to the envelope of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to and exploits angiotensin-converting…”
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4
Integrin and PD-1 Ligand Expression on Circulating Extracellular Vesicles in Systemic Inflammatory Response Syndrome and Sepsis
Published in Shock (Augusta, Ga.) (01-07-2019)“…ABSTRACTExtracellular vesicles (EVs) in the plasma mediate important intercellular communications in the pathogenesis of cancer and inflammatory diseases. EVs…”
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Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin
Published in Frontiers in cell and developmental biology (26-10-2020)“…Integrins are transmembrane proteins that mediate cellular adhesion and migration to neighboring cells or the extracellular matrix, which is essential for…”
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Sepsis Induces Deregulation of IL-13 Production and PD-1 Expression in Lung Group 2 Innate Lymphoid Cells
Published in Shock (Augusta, Ga.) (01-03-2021)“…ABSTRACTDeregulation of the immune system in sepsis plays the central role in the pathogenesis of multiple organ failure including septic lung injury. Group 2…”
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Integrating indigenous knowledge and culture in sustainable forest management via global environmental policies
Published in Journal of forest science (Praha) (25-06-2024)“…This research investigates the intricate connection between indigenous knowledge and sustainable forest management, with two main objectives. It seeks to…”
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Irisin supports integrin-mediated cell adhesion of lymphocytes
Published in Biochemistry and biophysics reports (01-07-2021)“…Irisin, a myokine released from skeletal muscle, has recently been found to act as a ligand for the integrins αVβ5, αVβ1, and α5β1 expressed on mesenchymal…”
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Microbial Contamination of Herbal Medicines in Africa, 2000-2024: A Systematic Review
Published in Environmental health insights (01-01-2024)“…Introduction: Herbal medicine has been a cornerstone of healthcare for centuries, with an estimated 80% of the world’s population relying on it. In Africa,…”
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Potential Roles of Muscle-Derived Extracellular Vesicles in Remodeling Cellular Microenvironment: Proposed Implications of the Exercise-Induced Myokine, Irisin
Published in Frontiers in cell and developmental biology (05-02-2021)“…Extracellular vesicles (EVs) have emerged as key players of intercellular communication and mediate crosstalk between tissues. Metastatic tumors release…”
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Anti-adhesive effects of human soluble thrombomodulin and its domains
Published in Biochemical and biophysical research communications (02-04-2019)“…We reported previously that leukocyte β2 integrins (LFA-1 and Mac-1) bind to the serine/threonine-rich domain of thrombomodulin (TM) expressed on vascular…”
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Exosomal regulation of lymphocyte homing to the gut
Published in Blood advances (08-01-2019)“…Exosomes secreted from T cells have been shown to affect dendritic cells, cancer cells, and other T cells. However, little is known about how T-cell exosomes…”
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The Potential of Bacteriophage-Antibiotic Combination Therapy in Treating Infections with Multidrug-Resistant Bacteria
Published in Antibiotics (Basel) (01-08-2023)“…The growing threat of antibiotic resistance is a significant global health challenge that has intensified in recent years. The burden of antibiotic resistance…”
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A Systematic Review on Antimicrobial Resistance in Ghana from a One Health Perspective
Published in Antibiotics (Basel) (01-07-2024)“…Antimicrobial resistance (AMR) poses a global health threat, with lower-middle-income countries bearing a disproportionate burden. Surveillance of AMR under a…”
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Sepsis-Related Lung Injury and the Complication of Extrapulmonary Pneumococcal Pneumonia
Published in Diseases (01-04-2024)“…Globally, sepsis and pneumonia account for significant mortality and morbidity. A complex interplay of immune-molecular pathways underlies both sepsis and…”
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Reservoirs of Nosocomial Pathogens in Intensive Care Units: A Systematic Review
Published in Environmental health insights (01-01-2024)“…Nosocomial pathogens are known to exacerbate morbidity and mortality in contemporary critical healthcare. Hospital fomites, which include inanimate surfaces,…”
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Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
Published in Biomedicines (18-07-2019)“…Sepsis is a systemically dysregulated inflammatory syndrome, in which dendritic cells (DCs) play a critical role in coordinating aberrant immunity. The aim of…”
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Inflation, Exchange Rates and Interest Rates in Ghana: an Autoregressive Distributed Lag Model
Published in Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis (2015)“…This paper investigates the impact of exchange rate movement and the nominal interest rate on inflation in Ghana. It also looks at the presence of the Fisher…”
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The Lectin-Like Domain of Thrombomodulin Inhibits β1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin
Published in Biomedicines (07-02-2021)“…Thrombomodulin is a molecule with anti-coagulant and anti-inflammatory properties. Recently, thrombomodulin was reported to be able to bind extracellular…”
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Achieving Sustainable Development Goals in Ghana: The Contribution of Non-Timber Forest Products towards Economic Development in the Eastern Region
Published in Land (Basel) (01-03-2023)“…Globally, non-timber forest products (NTFPs) continue to contribute vastly to addressing the food, poverty reduction, income, and livelihood requirements of…”
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