Search Results - "Daris, Kristi"

Dickkopf‐1 regulates bone formation in young growing rodents and upon traumatic injury by Li, Xiaodong, Grisanti, Mario, Fan, Wei, Asuncion, Frank J, Tan, Hong‐Lin, Dwyer, Denise, Han, Chun‐Ya, Yu, Longchuan, Lee, Jae, Lee, Edward, Barrero, Mauricio, Kurimoto, Pam, Niu, Qing‐Tian, Geng, Zhaopo, Winters, Aaron, Horan, Tom, Steavenson, Shirley, Jacobsen, Frederick, Chen, Qing, Haldankar, Raj, Lavallee, Jennifer, Tipton, Barbara, Daris, Mark, Sheng, Jackie, Lu, Hsieng S, Daris, Kristi, Deshpande, Rohini, Valente, Eliane G, Salimi‐Moosavi, Hossein, Kostenuik, Paul J, Li, Ji, Liu, Min, Li, Chaoyang, Lacey, David L, Simonet, W Scott, Ke, Hua Zhu, Babij, Philip, Stolina, Marina, Ominsky, Michael S, Richards, William G

“…The physiological role of Dickkopf‐1 (Dkk1) during postnatal bone growth in rodents and in adult rodents was examined utilizing an antibody to Dkk1 (Dkk1‐Ab)…”
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Stop-Codon Readthrough in Therapeutic Protein Candidates Expressed from Mammalian Cells by Zhang, Zhongqi, Khanal, Neelam, Dykstra, Andrew B, Daris, Kristi

“…Stop codon readthroughs were examined in 48 recombinant therapeutic protein candidates produced from multiple clones of Chinese hamster ovary cells, using…”
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Characterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line by Tharmalingam, Tharmala, Barkhordarian, Hedieh, Tejeda, Nicole, Daris, Kristi, Yaghmour, Sam, Yam, Pheng, Lu, Fang, Goudar, Chetan, Munro, Trent, Stevens, Jennitte

“…Regulatory guidelines require the sponsors to provide assurance of clonality of the production cell line, and when such evidence is not available, additional…”
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Culture temperature modulates half antibody and aggregate formation in a Chinese hamster ovary cell line expressing a bispecific antibody by Gomez, Natalia, Wieczorek, Agatha, Lu, Fang, Bruno, Richele, Diaz, Luis, Agrawal, Neeraj J., Daris, Kristi

“…Therapeutic bispecific antibodies are formed by assembly of multichain polypeptides. In general, a bispecific antibody has two different light chains and two…”
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Methods for Estimating the Probability of Clonality in Cell Line Development by Chen, Chun, Le, Kim, Le, Huong, Daris, Kristi, Soice, Neil, Stevens, Jennitte, Goudar, Chetan T.

“…Mammalian cell banks for biopharmaceutical production are usually derived from a single progenitor cell. Different methods to estimate the probability that the…”
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Investigation of the free heavy chain homodimers of a monoclonal antibody by Chung, Hyo (Helen), Buck, Lynette, Daris, Kristi, Welborn, Brent, Luo, Quanzhou, Wypych, Jette

“…Monoclonal antibodies (mAbs) are composed of two heavy chain (HC) and two light chain (LC) polypeptides. The proper folding and assembly of HC and LC is…”
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Cell line profiling to improve monoclonal antibody production by Kang, Sohye, Ren, Da, Xiao, Gang, Daris, Kristi, Buck, Lynette, Enyenihi, Atim A., Zubarev, Roman, Bondarenko, Pavel V., Deshpande, Rohini

“…ABSTRACT Mammalian cell culture performance is influenced by both intrinsic (genetic) and extrinsic (media and process) factors. In this study, intrinsic…”
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