Search Results - "Dargan, Paul I."

Gadolinium deposition and the potential for toxicological sequelae – A literature review of issues surrounding gadolinium‐based contrast agents by Layne, Kerry A., Dargan, Paul I., Archer, John R. H., Wood, David M.

“…Every year, approximately 30 million magnetic resonance imaging scans are enhanced with gadolinium‐based contrast agents (GBCAs) worldwide. Although the…”
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Rhabdomyolysis related to acute recreational drug toxicity-A Euro-DEN study by Waldman, Wojciech, Kabata, Piotr M, Dines, Alison M, Wood, David M, Yates, Christopher, Heyerdahl, Fridtjof, Hovda, Knut Erik, Giraudon, Isabelle, Dargan, Paul I, Sein Anand, Jacek

“…This study was conducted to retrospectively assess the relationships between: rhabdomyolysis (quantified by creatine kinase (CK) activity) and kidney injury…”
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E-cigarette or vaping-associated lung injury (EVALI): a review of international case reports from outside the United States of America by Sund, Lachlan J., Dargan, Paul I., Archer, John R. H., Wood, David M.

“…E-cigarette or vaping-associated lung injury has been reported extensively throughout the United States without a corresponding number of international cases…”
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Outbreak of Fatal Childhood Lead Poisoning Related to Artisanal Gold Mining in Northwestern Nigeria, 2010 by Dooyema, Carrie A., Neri, Antonio, Lo, Yi-Chun, Durant, James, Dargan, Paul I., Swarthout, Todd, Biya, Oladayo, Gidado, Saheed O., Haladu, Suleiman, Sani-Gwarzo, Nasir, Nguku, Patrick M., Akpan, Henry, Idris, Sa'ad, Bashir, Abdullahi M., Brown, Mary Jean

“…Background: In May 2010, a team of national and international organizations was assembled to investigate children's deaths due to lead poisoning in villages in…”
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Outcomes from massive paracetamol overdose: a retrospective observational study by Marks, Daniel J. B., Dargan, Paul I., Archer, John R. H., Davies, Charlotte L., Dines, Alison M., Wood, David M., Greene, Shaun L.

“…LINKED ARTICLE This article is commented on by Bateman DN and Dear JW. Should we treat very large paracetamol overdose differently? Br J Clin Pharmacol 2017;…”
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Polonium-210 poisoning: a first-hand account by Nathwani, Amit C, Dr, Down, James F, MBBS, Goldstone, John, MBBS, Yassin, James, MBBS, Dargan, Paul I, MBBS, Virchis, Andres, MBBS, Gent, Nick, MBChB, Lloyd, David, PhD, Harrison, John D, PhD

“…Summary Background Polonium-210 (210 Po) gained widespread notoriety after the poisoning and subsequent death of Mr Alexander Litvinenko in London, UK, in…”
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Challenges in the diagnosis of ethylene glycol poisoning by McQuade, David J, Dargan, Paul I, Wood, David M

“…Ethylene glycol poisoning, while uncommon, is clinically significant due to the associated risk of severe morbidity or lethality and it continues to occur in…”
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The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone) by Dargan, Paul I., Sedefov, Roumen, Gallegos, Ana, Wood, David M.

“…Mephedrone (4‐methylmethcathinone) is a synthetic cathinone that is used as a recreational drug. It has been available since 2007 but its availability and use…”
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Non-medical Use of Prescription Gabapentinoids (Gabapentin and Pregabalin) in Five European Countries by Fonseca, Francina, Lenahan, William, Dart, Richard C, Papaseit, Esther, Dargan, Paul I, Wood, David M, Guareschi, Marilena, Maremmani, Icro, Auriacombe, Marc, Farré, Magí, Scherbaum, Norbert, Torrens, Marta

“…Non-medical use (NMU) of prescription GABA analogs (pregabalin and gabapentin) has been reported especially in opiate dependent persons. However, by now the…”
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Description of 3,180 courses of chelation with dimercaptosuccinic acid in children ≤ 5 y with severe lead poisoning in Zamfara, Northern Nigeria: a retrospective analysis of programme data by Thurtle, Natalie, Greig, Jane, Cooney, Lauren, Amitai, Yona, Ariti, Cono, Brown, Mary Jean, Kosnett, Michael J, Moussally, Krystel, Sani-Gwarzo, Nasir, Akpan, Henry, Shanks, Leslie, Dargan, Paul I

“…In 2010, Médecins Sans Frontières (MSF) discovered extensive lead poisoning impacting several thousand children in rural northern Nigeria. An estimated 400…”
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The EXTRIP (EXtracorporeal TReatments In Poisoning) workgroup: Guideline methodology by Lavergne, Valéry, Nolin, Thomas D., Hoffman, Robert S., Roberts, Darren, Gosselin, Sophie, Goldfarb, David S., Kielstein, Jan T., Mactier, Robert, Maclaren, Robert, Mowry, James B., Bunchman, Timothy E., Juurlink, David, Megarbane, Bruno, Anseeuw, Kurt, Winchester, James F., Dargan, Paul I., Liu, Kathleen D., Hoegberg, Lotte C., Li, Yi, Calello, Diane P., Burdmann, Emmanuel A., Yates, Christopher, Laliberté, Martin, Decker, Brian Scott, Mello-Da-Silva, Carlos Augusto, Lavonas, Eric, Ghannoum, Marc

“…Abstract Extracorporeal treatments (ECTRs), such as hemodialysis and hemoperfusion, are used in poisoning despite a lack of controlled human trials…”
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Association of blood lead level with neurological features in 972 children affected by an acute severe lead poisoning outbreak in Zamfara State, northern Nigeria by Greig, Jane, Thurtle, Natalie, Cooney, Lauren, Ariti, Cono, Ahmed, Abdulkadir Ola, Ashagre, Teshome, Ayela, Anthony, Chukwumalu, Kingsley, Criado-Perez, Alison, Gómez-Restrepo, Camilo, Meredith, Caitlin, Neri, Antonio, Stellmach, Darryl, Sani-Gwarzo, Nasir, Nasidi, Abdulsalami, Shanks, Leslie, Dargan, Paul I

“…In 2010, Médecins Sans Frontières (MSF) investigated reports of high mortality in young children in Zamfara State, Nigeria, leading to confirmation of villages…”
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Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers by Czerwinska, Joanna, Parkin, Mark C, Cilibrizzi, Agostino, George, Claire, Kicman, Andrew T, Dargan, Paul I, Abbate, Vincenzo

“…Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: -(+)-mephedrone and…”
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Self-discharge during treatment for acute recreational drug toxicity: an observational study from emergency departments in seven European countries by Vallersnes, Odd Martin, Dines, Alison M., Wood, David M., Heyerdahl, Fridtjof, Hovda, Knut Erik, Yates, Christopher, Giraudon, Isabelle, Caganova, Blazena, Ceschi, Alessandro, Galicia, Miguel, Liakoni, Evangelia, Liechti, Matthias E., Miró, Òscar, Noseda, Roberta, Persett, Per Sverre, Põld, Kristiina, Schmid, Yasmin, Scholz, Irene, Vigorita, Federico, Dargan, Paul I.

“…Background Self-discharge is a risk factor for readmission and excess mortality. We assess the rate of self-discharge from the emergency department (ED) among…”
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Safety and Efficacy of the SNAP 12-hour Acetylcysteine Regimen for the Treatment of Paracetamol Overdose by Pettie, Janice M, Caparrotta, Thomas M, Hunter, Robert W, Morrison, Emma E, Wood, David M, Dargan, Paul I, Thanacoody, Ruben H, Thomas, Simon H L, Elamin, Muhammad E M O, Francis, Ben, Webb, David J, Sandilands, Euan A, Eddleston, Michael, Dear, James W

“…Acetylcysteine (NAC) is effective at preventing liver injury after paracetamol overdose. The Scottish and Newcastle Anti-emetic Pre-treatment for Paracetamol…”
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Correction: Neonatal blood lead concentration predicts medium term lead-related outcomes in children ≤5 years old with congenital lead poisoning: A retrospective cohort study in Northern Nigeria by Thurtle, Natalie, Kirby, Katharine A, Greig, Jane, Bil, Karla, Dargan, Paul I, Ntadom, Godwin N, Buckley, Nicholas A

“…[This corrects the article DOI: 10.1371/journal.pgph.0001644.]…”
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Comparative Untargeted Metabolomics Analysis of the Psychostimulants 3,4-Methylenedioxy-Methamphetamine (MDMA), Amphetamine, and the Novel Psychoactive Substance Mephedrone after Controlled Drug Administration to Humans by Steuer, Andrea E., Kaelin, Daria, Boxler, Martina I., Eisenbeiss, Lisa, Holze, Friederike, Vizeli, Patrick, Czerwinska, Joanna, Dargan, Paul I., Abbate, Vincenzo, Liechti, Matthias E., Kraemer, Thomas

“…Psychoactive stimulants are a popular drug class which are used recreationally. Over the last decade, large numbers of new psychoactive substances (NPS) have…”
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Relative safety of hyperinsulinaemia/euglycaemia therapy in the management of calcium channel blocker overdose : a prospective observational study by GREENE, Shaun L, GAWARAMMANA, Indika, WOOD, David M, JONES, Alison L, DARGAN, Paul I

“…To examine the clinical safety of hyperinsulinaemia/euglycaemia therapy (HIET) in calcium channel blocker (CCB) poisoning. A prospective observational study…”
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Neonatal blood lead concentration predicts medium term lead-related outcomes in children ≤5 years old with congenital lead poisoning: A retrospective cohort study in Northern Nigeria by Thurtle, Natalie, Kirby, Katharine A, Greig, Jane, Bil, Karla, Dargan, Paul I, Ntadom, Godwin N, Buckley, Nicholas A

“…Mother-to-child-transmission of lead via the placenta is known to result in congenital lead toxicity. Between 2010 and 2021, Médecins Sans Frontières and other…”
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Extracorporeal Treatment for Thallium Poisoning: Recommendations from the EXTRIP Workgroup by Ghannoum, Marc, Nolin, Thomas D, Goldfarb, David S, Roberts, Darren M, Mactier, Robert, Mowry, James B, Dargan, Paul I, Maclaren, Robert, Hoegberg, Lotte C, Laliberté, Martin, Calello, Diane, Kielstein, Jan T, Anseeuw, Kurt, Winchester, James F, Burdmann, Emmanuel A, Bunchman, Timothy E, Li, Yi, Juurlink, David N, Lavergne, Valery, Megarbane, Bruno, Gosselin, Sophie, Liu, Kathleen D, Hoffman, Robert S

“…The EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup was formed to provide recommendations on the use of extracorporeal treatment (ECTR) in poisoning…”
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